Browse result page of PRRDB 2.0

PRRID	Name of Ligand	Source of ligand	Sequence of Ligand	Length of Ligand	Type of Ligand	Occurence	Role of Ligand	Name of Receptor	Type of Reeptor	Source of the Receptor	Localization	Domain	Sequence of Receptor	Swiss prot ID	Length of receptor	Function of Receptor	Assay used	PMID	Year of publication	Pubchem assay
PRRID_0035	Advanced Glycation End Products (AGE) Click for more detail	NA	NA	NA	Protein	Natural	It leads to the formation of high molecular weight aggregates.	Galectin-3	Pattern recognition receptor (PRR)	Rat	Macrophage-like RAW264.7 cells	NA	NA	NA	NA	It contributes to the elimination of pathogenic substances such as AGE.	Binding assay	8529130	1995	NA
PRRID_0035	Advanced Glycation End Products (AGE) Click for more detail	NA	NA	NA	Protein	Natural	It leads to the formation of high molecular weight aggregates.	Galectin-3	Pattern recognition receptor (PRR)	Rat	Macrophage-like RAW264.7 cells	NA	NA	NA	NA	It contributes to the elimination of pathogenic substances such as AGE.	Binding assay	8529130	1995	NA
PRRID_0049	Fractionated [(3)H]heparin Click for more detail	Host (Endogenous) (others)	CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O	NA	Glycosaminoglycan	Natural	Fractionated [(3)H]heparin is a potent ligand for scavenger receptor A-I	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	Rat	Kupffer cells	NA	NA	NA	NA	Adsorptive endocytosis of polypeptides and phagocytosis.	NA	8860963	1996	NA
PRRID_0049	Fractionated [(3)H]heparin Click for more detail	Host (Endogenous) (others)	CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O	NA	Glycosaminoglycan	Natural	Fractionated [(3)H]heparin is a potent ligand for scavenger receptor A-I	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	Rat	Kupffer cells	NA	NA	NA	NA	Adsorptive endocytosis of polypeptides and phagocytosis.	NA	8860963	1996	NA
PRRID_0309	Lipopolysaccharide (LPS) Click for more detail	Escherichia coli (055:B5) (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	It leads to the activation of the transcription factor nuclear factor kappa B (NFKB) in caput and cauda epididymides.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	Epididymis	LRR	NA	NA	NA	Rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia coli through activation of Tolllike receptor 4.	EMSA	18703421	2008	NA
PRRID_0309	Lipopolysaccharide (LPS) Click for more detail	Escherichia coli (055:B5) (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	It leads to the activation of the transcription factor nuclear factor kappa B (NFKB) in caput and cauda epididymides.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	Epididymis	LRR	NA	NA	NA	Rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia coli through activation of Tolllike receptor 4.	EMSA	18703421	2008	NA
PRRID_0562	HMGB1 Click for more detail	Human (others)	MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE	215	Protein	Natural	It interacts with the TLR4 and elicit immune response	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	Endothelial cells	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	It induced vascular endothelial activation	EMSA	20714791	2010	Pubchem Assay
PRRID_0562	HMGB1 Click for more detail	Human (others)	MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE	215	Protein	Natural	It interacts with the TLR4 and elicit immune response	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	Endothelial cells	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	It induced vascular endothelial activation	EMSA	20714791	2010	Pubchem Assay
PRRID_0632	Lipopolysaccharide (LPS) Click for more detail	Gram-negative bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	myocardium	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	NA	NA	20697548	2010	Pubchem Assay
PRRID_0632	Lipopolysaccharide (LPS) Click for more detail	Gram-negative bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	myocardium	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	NA	NA	20697548	2010	Pubchem Assay
PRRID_0633	Lipopolysaccharide (LPS) Click for more detail	Gram-negative bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	NA	sCD14	Pattern recognition receptor (PRR)	Rat	myocardium	NA	Q63691.fasta	Q63691	372	NA	NF-	20697548	2010	Pubchem Assay
PRRID_0633	Lipopolysaccharide (LPS) Click for more detail	Gram-negative bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	NA	sCD14	Pattern recognition receptor (PRR)	Rat	myocardium	NA	Q63691.fasta	Q63691	372	NA	NF-	20697548	2010	Pubchem Assay
PRRID_0639	Lipopolysaccharide (LPS) Click for more detail	Escherichia coli serotype 0127:B8 (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Binding of LPS trigger the NFKB pathway.	cluster of differentiation 14 (CD14)	Pattern recognition receptor (PRR)	Wistar Rat	Pineal gland (pinealocytes)	NA	Q63691.fasta	Q63691	372	The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF and inhibiting melatonin synthesis	NA	20586888	2010	Pubchem Assay
PRRID_0639	Lipopolysaccharide (LPS) Click for more detail	Escherichia coli serotype 0127:B8 (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Binding of LPS trigger the NFKB pathway.	cluster of differentiation 14 (CD14)	Pattern recognition receptor (PRR)	Wistar Rat	Pineal gland (pinealocytes)	NA	Q63691.fasta	Q63691	372	The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF and inhibiting melatonin synthesis	NA	20586888	2010	Pubchem Assay
PRRID_0640	Lipopolysaccharide (LPS) Click for more detail	Escherichia coli serotype 0127:B9 (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Binding of LPS trigger the NFKB pathway and inducing a local synthesis of the cytokine TNF, and the TNF receptor 1 (TNFR1) up-regulation in pinealocytes	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Wistar Rat	Pineal gland (pinealocytes)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF by inhibiting the NE-induced melatonin biosynthetic pathway and mount the inflammatory response	EMSA	20586888	2010	Pubchem Assay
PRRID_0640	Lipopolysaccharide (LPS) Click for more detail	Escherichia coli serotype 0127:B9 (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Binding of LPS trigger the NFKB pathway and inducing a local synthesis of the cytokine TNF, and the TNF receptor 1 (TNFR1) up-regulation in pinealocytes	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Wistar Rat	Pineal gland (pinealocytes)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF by inhibiting the NE-induced melatonin biosynthetic pathway and mount the inflammatory response	EMSA	20586888	2010	Pubchem Assay
PRRID_0718	OM-174 Click for more detail	E. coli(Bacteria)	CCCCCCCCCCC[C@@H](O)CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]2NC(=O)C[C@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@@H]1OP(O)(O)=O	NA	Lipid	Natural	it induce the expression of iNOS, tumour suppressive proteins and cytokines	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	Liver	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It results into inhibition of invasion and metastasis of HCC	NA	20675699	2010	NA
PRRID_0718	OM-174 Click for more detail	E. coli(Bacteria)	CCCCCCCCCCC[C@@H](O)CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]2NC(=O)C[C@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@@H]1OP(O)(O)=O	NA	Lipid	Natural	it induce the expression of iNOS, tumour suppressive proteins and cytokines	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	Liver	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It results into inhibition of invasion and metastasis of HCC	NA	20675699	2010	NA
PRRID_1017	V. vulnificus Click for more detail	Bacteria	NA	NA	NA	Natural	NA	LmGNBP3	Gram-negative Bacteria-binding Protein (GNBPs)	Locusta migRatoria	NA	b-1,3-glu- canase-like domain	NA	NA	NA	NA	16S rRNA gene analysis	22062247	2012	NA
PRRID_1017	V. vulnificus Click for more detail	Bacteria	NA	NA	NA	Natural	NA	LmGNBP3	Gram-negative Bacteria-binding Protein (GNBPs)	Locusta migRatoria	NA	b-1,3-glu- canase-like domain	NA	NA	NA	NA	16S rRNA gene analysis	22062247	2012	NA
PRRID_1914	Amyloid-Œ≤ fibrils Click for more detail	NA	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN	770	Damage-associated molecular patterns (DAMPs)	Natural	Immunostimulant	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_1914	Amyloid-Œ≤ fibrils Click for more detail	NA	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN	770	Damage-associated molecular patterns (DAMPs)	Natural	Immunostimulant	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_1917	Anthrax lethal toxin Click for more detail	NA	NA	NA	Protein	Natural	NA	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Rat	Hippocampus	NA	D9I2G4 .fasta	D9I2G4	1218	NLRP1 inflammasome activation in aging	NA	28801521	2017	Pubchem_assay
PRRID_1917	Anthrax lethal toxin Click for more detail	NA	NA	NA	Protein	Natural	NA	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Rat	Hippocampus	NA	D9I2G4 .fasta	D9I2G4	1218	NLRP1 inflammasome activation in aging	NA	28801521	2017	Pubchem_assay
PRRID_1929	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_1929	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_2124	Heat-shock protein 70 Click for more detail	NA	MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD	641	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2124	Heat-shock protein 70 Click for more detail	NA	MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD	641	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2128	Heat-shock protein 70 Click for more detail	NA	MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD	641	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat hippocampus (microglia)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	mRNA ‚Üë in postoperative cognitive dysfunction in senile animals	NA	28801521	2017	Pubchem_assay
PRRID_2128	Heat-shock protein 70 Click for more detail	NA	MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD	641	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat hippocampus (microglia)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	mRNA ‚Üë in postoperative cognitive dysfunction in senile animals	NA	28801521	2017	Pubchem_assay
PRRID_2132	Heat-shock protein 70 Click for more detail	NA	MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD	641	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2132	Heat-shock protein 70 Click for more detail	NA	MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD	641	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2142	Heat-shock proteins 60 Click for more detail	NA	MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF	573	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2142	Heat-shock proteins 60 Click for more detail	NA	MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF	573	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2146	Heat-shock proteins 60 Click for more detail	NA	MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF	573	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat hippocampus (microglia)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	mRNA ‚Üë in postoperative cognitive dysfunction in senile animals	NA	28801521	2017	Pubchem_assay
PRRID_2146	Heat-shock proteins 60 Click for more detail	NA	MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF	573	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat hippocampus (microglia)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	mRNA ‚Üë in postoperative cognitive dysfunction in senile animals	NA	28801521	2017	Pubchem_assay
PRRID_2150	Heat-shock proteins 60 Click for more detail	NA	MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF	573	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2150	Heat-shock proteins 60 Click for more detail	NA	MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF	573	Damage-associated molecular patterns (DAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2188	HMGB1 Click for more detail	NA	MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE	215	Protein	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2188	HMGB1 Click for more detail	NA	MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE	215	Protein	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2192	HMGB1 Click for more detail	NA	MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE	215	Protein	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat hippocampus (microglia)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	mRNA ‚Üë in postoperative cognitive dysfunction in senile animals	NA	28801521	2017	Pubchem_assay
PRRID_2192	HMGB1 Click for more detail	NA	MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE	215	Protein	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat hippocampus (microglia)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	mRNA ‚Üë in postoperative cognitive dysfunction in senile animals	NA	28801521	2017	Pubchem_assay
PRRID_2196	HMGB1 Click for more detail	NA	MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE	215	Protein	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2196	HMGB1 Click for more detail	NA	MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE	215	Protein	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2261	Lipopolysaccharide (LPS) Click for more detail	Bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2261	Lipopolysaccharide (LPS) Click for more detail	Bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Rat	rat brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q9QX05.fasta	Q9QX05	835	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2292	Lipoprotein Click for more detail	Bacteria	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	hippocampus (microglia)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	mRNA ‚Üë in postoperative cognitive dysfunction in senile animals	NA	28801521	2017	Pubchem_assay
PRRID_2292	Lipoprotein Click for more detail	Bacteria	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	hippocampus (microglia)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	mRNA ‚Üë in postoperative cognitive dysfunction in senile animals	NA	28801521	2017	Pubchem_assay
PRRID_2295	Lipoprotein Click for more detail	Bacteria	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2295	Lipoprotein Click for more detail	Bacteria	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Rat	brain (vasculature)	Leucine-rich Repeat (LRR) Domain	Q6YGU2.fasta	Q6YGU2	784	protein ‚Üë, activation in ischemic stroke	NA	28801521	2017	Pubchem_assay
PRRID_2333	MDP (muramyldipeptide) Click for more detail	Gram-negative and Gram-positive bacteria	CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C	NA	Peptide	Natural	NA	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Rat	Hippocampus	NA	D9I2G4 .fasta	D9I2G4	1218	NLRP1 inflammasome activation in aging	NA	28801521	2017	Pubchem_assay
PRRID_2333	MDP (muramyldipeptide) Click for more detail	Gram-negative and Gram-positive bacteria	CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C	NA	Peptide	Natural	NA	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Rat	Hippocampus	NA	D9I2G4 .fasta	D9I2G4	1218	NLRP1 inflammasome activation in aging	NA	28801521	2017	Pubchem_assay
PRRID_2341	MDP (muramyldipeptide) Click for more detail	Gram-negative and Gram-positive bacteria	CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C	NA	Peptide	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	NA	NA	NA	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	NA
PRRID_2341	MDP (muramyldipeptide) Click for more detail	Gram-negative and Gram-positive bacteria	CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C	NA	Peptide	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	NA	NA	NA	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	NA
PRRID_2438	NA Click for more detail	S. cerevisiae (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	elicit innate immune response	CREP4	C type Lectin (CTL/CLR)	B. glabRata	NA	NA	NA	NA	NA	NA	transcriptomic data	29051762	2017	NA
PRRID_2438	NA Click for more detail	S. cerevisiae (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	elicit innate immune response	CREP4	C type Lectin (CTL/CLR)	B. glabRata	NA	NA	NA	NA	NA	NA	transcriptomic data	29051762	2017	NA
PRRID_2446	NA Click for more detail	S. mansoni (others)	NA	NA	Protein	Natural	NA	Œ±-amylases	enzymes interacting with pathogens (EIP)	B. glabRata	NA	NA	NA	NA	NA	NA	NA	29051762	2017	NA
PRRID_2446	NA Click for more detail	S. mansoni (others)	NA	NA	Protein	Natural	NA	Œ±-amylases	enzymes interacting with pathogens (EIP)	B. glabRata	NA	NA	NA	NA	NA	NA	NA	29051762	2017	NA
PRRID_2502	Nigericin Click for more detail	NA	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_2502	Nigericin Click for more detail	NA	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_2598	ROS Click for more detail	NA	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_2598	ROS Click for more detail	NA	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_2674	Uric acid Click for more detail	NA	C12=C(NC(=O)N1)NC(=O)NC2=O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the synthesis of IL-1Œ≤, TNF-Œ± and TGF-Œ≤ by murine macrophages.	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay
PRRID_2674	Uric acid Click for more detail	NA	C12=C(NC(=O)N1)NC(=O)NC2=O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the synthesis of IL-1Œ≤, TNF-Œ± and TGF-Œ≤ by murine macrophages.	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Rat	primary astrocytes	NA	D4A523.fasta	D4A523	1035	protein ‚Üë, activation of NLRP3 inflammasome in PD models	NA	28801521	2017	Pubchem_assay

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