Primary information |
---|
PRRID | PRRID_0309 |
Ligand Name | Lipopolysaccharide (LPS) |
Source | Escherichia coli (055:B5) (Bacteria) |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Lipopolysaccharide (LPS) |
Occurence | Natural |
Role of Ligand | It leads to the activation of the transcription factor nuclear factor kappa B (NFKB) in caput and cauda epididymides. |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Rat |
Localization | Epididymis |
Domain | LRR |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | Rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia coli through activation of Tolllike receptor 4. |
Assay used | EMSA |
PMID | 18703421 |
Year of Publication | 2008 |
Pubchem assay | NA |
Primary information |
---|
PRRID | PRRID_0309 |
Ligand Name | Lipopolysaccharide (LPS) |
Source | Escherichia coli (055:B5) (Bacteria) |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Lipopolysaccharide (LPS) |
Occurence | Natural |
Role of Ligand | It leads to the activation of the transcription factor nuclear factor kappa B (NFKB) in caput and cauda epididymides. |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Rat |
Localization | Epididymis |
Domain | LRR |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | Rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia coli through activation of Tolllike receptor 4. |
Assay used | EMSA |
PMID | 18703421 |
Year of Publication | 2008 |
Pubchem assay | NA |