| Primary information |
|---|
| PRRID | PRRID_0309 |
| Ligand Name | Lipopolysaccharide (LPS) |
| Source | Escherichia coli (055:B5) (Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
| Length | NA |
| Type | Lipopolysaccharide (LPS) |
| Occurence | Natural |
| Role of Ligand | It leads to the activation of the transcription factor nuclear factor kappa B (NFKB) in caput and cauda epididymides. |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Rat |
| Localization | Epididymis |
| Domain | LRR |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | Rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia coli through activation of Tolllike receptor 4. |
| Assay used | EMSA |
| PMID | 18703421 |
| Year of Publication | 2008 |
| Pubchem assay | NA |
| Primary information |
|---|
| PRRID | PRRID_0309 |
| Ligand Name | Lipopolysaccharide (LPS) |
| Source | Escherichia coli (055:B5) (Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
| Length | NA |
| Type | Lipopolysaccharide (LPS) |
| Occurence | Natural |
| Role of Ligand | It leads to the activation of the transcription factor nuclear factor kappa B (NFKB) in caput and cauda epididymides. |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Rat |
| Localization | Epididymis |
| Domain | LRR |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | Rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia coli through activation of Tolllike receptor 4. |
| Assay used | EMSA |
| PMID | 18703421 |
| Year of Publication | 2008 |
| Pubchem assay | NA |