Detailed description page of PRRDB2.0

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PRRID_0562 details
Primary information
PRRIDPRRID_0562
Ligand NameHMGB1
SourceHuman (others)
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of LigandIt interacts with the TLR4 and elicit immune response
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Rat
LocalizationEndothelial cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QX05.fasta
Swiss prot IDQ9QX05
Length Of Receptor835
FunctionIt induced vascular endothelial activation
Assay usedEMSA
PMID20714791
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0562
Ligand NameHMGB1
SourceHuman (others)
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of LigandIt interacts with the TLR4 and elicit immune response
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Rat
LocalizationEndothelial cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QX05.fasta
Swiss prot IDQ9QX05
Length Of Receptor835
FunctionIt induced vascular endothelial activation
Assay usedEMSA
PMID20714791
Year of Publication2010
Pubchem assayPubchem Assay