Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_1802mannitol-linked glycerogly- colipid

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp. (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1802mannitol-linked glycerogly- colipid

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp. (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1803Mannose

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HIV-1 (virus)C(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDCIRC type Lectin (CTL/CLR)HumanNANANANANAInhibition of APC functions such as cytokine productionNA279999922016NA
PRRID_1803Mannose

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HIV-1 (virus)C(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDCIRC type Lectin (CTL/CLR)HumanNANANANANAInhibition of APC functions such as cytokine productionNA279999922016NA
PRRID_1804Mannose

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusC(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1804Mannose

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusC(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1805mannosyl fatty acids

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1805mannosyl fatty acids

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1806Mj arrestin2

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NANANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMjSRCScavenger receptor (SR)Marsupenaeus japonicusHemocytestwo CCP domains, a MAM domain, a transmembrane region and an intracellular regionA0A1L2DC21.fastaA0A1L2DC21692antiviral role by enhancing hemo- cytes phagocytosis of WSSV in shrimp.NA280273192016Pubchem_assay
PRRID_1806Mj arrestin2

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NANANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMjSRCScavenger receptor (SR)Marsupenaeus japonicusHemocytestwo CCP domains, a MAM domain, a transmembrane region and an intracellular regionA0A1L2DC21.fastaA0A1L2DC21692antiviral role by enhancing hemo- cytes phagocytosis of WSSV in shrimp.NA280273192016Pubchem_assay
PRRID_1810NA

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Propionibacterium acnes (Bacteria)NANAPattern-associated molecular patterns (PAMPs)Naturalrole in acne vulgaris, contributing factor to the progression of prostate cancer and likely through the activation of NF-κB pathwayToll-like receptor 2 (TLR2)homodimersToll-like receptor (TLR)MiceNALeucine-rich Repeat (LRR) DomainNANANAinduced NF-κB and AP-1activationELISA280249242016NA
PRRID_1810NA

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Propionibacterium acnes (Bacteria)NANAPattern-associated molecular patterns (PAMPs)Naturalrole in acne vulgaris, contributing factor to the progression of prostate cancer and likely through the activation of NF-κB pathwayToll-like receptor 2 (TLR2)homodimersToll-like receptor (TLR)MiceNALeucine-rich Repeat (LRR) DomainNANANAinduced NF-κB and AP-1activationELISA280249242016NA
PRRID_1811NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 22 (TLR22)Toll-like receptor (TLR)Megalobrama amblycephalablood, head kidney, spleen and intestine16 leucine-rich repeat (LRR) motifs, an LRR C-terminal, a transmembrane region and a cytoplasmic toll–interleukin-1 receptor (TIR) domain.A0A2H4IQ59.fastaA0A2H4IQ59946Activate NF-KBNA279432922016Pubchem_assay
PRRID_1811NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 22 (TLR22)Toll-like receptor (TLR)Megalobrama amblycephalablood, head kidney, spleen and intestine16 leucine-rich repeat (LRR) motifs, an LRR C-terminal, a transmembrane region and a cytoplasmic toll–interleukin-1 receptor (TIR) domain.A0A2H4IQ59.fastaA0A2H4IQ59946Activate NF-KBNA279432922016Pubchem_assay
PRRID_1812NA

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Vibrio harveyi (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantPmCLecC type Lectin (CTL/CLR)Penaeus monodonlymphoid organ.carbohydrate recognition domain (CRD)NANANAActivate NF-KBMicrobial binding assay278766222016NA
PRRID_1812NA

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Vibrio harveyi (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantPmCLecC type Lectin (CTL/CLR)Penaeus monodonlymphoid organ.carbohydrate recognition domain (CRD)NANANAActivate NF-KBMicrobial binding assay278766222016NA
PRRID_1813NA

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RS218 (E.coli strain) (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalCauses inflammation and activation of SCR.SSc5DScavenger receptor (SR)HumanMacrophagesFive SRCR modules, and a large C-terminal mucin-like domainA1L4H1.fastaA1L4H11573Pathogen recognition; T cell differentiationMicrobial binding assay277902152016Pubchem_assay
PRRID_1813NA

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RS218 (E.coli strain) (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalCauses inflammation and activation of SCR.SSc5DScavenger receptor (SR)HumanMacrophagesFive SRCR modules, and a large C-terminal mucin-like domainA1L4H1.fastaA1L4H11573Pathogen recognition; T cell differentiationMicrobial binding assay277902152016Pubchem_assay
PRRID_1814NA

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IHE3034 (E.coli strain) (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalCauses inflammation and activation of SCR.SSc5DScavenger receptor (SR)HumanMacrophagesFive SRCR modules, and a large C-terminal mucin-like domainA1L4H1.fastaA1L4H11573Pathogen recognition; T cell differentiationMicrobial binding assay277902152016Pubchem_assay
PRRID_1814NA

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IHE3034 (E.coli strain) (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalCauses inflammation and activation of SCR.SSc5DScavenger receptor (SR)HumanMacrophagesFive SRCR modules, and a large C-terminal mucin-like domainA1L4H1.fastaA1L4H11573Pathogen recognition; T cell differentiationMicrobial binding assay277902152016Pubchem_assay
PRRID_1815NA

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Uropathogenic E.coli (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 10 (TLR10)Toll-like receptor (TLR)Micebladder epithelial cellsextracellular domain containing leucine-rich repeats and an intracellular domain that contains a conserved region called the Toll/IL-1 receptor (TIR) domain and the trans membrane domainQ6R5P0.fastaQ6R5P0926Activate NF-KBNA277566042016Pubchem_assay
PRRID_1815NA

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Uropathogenic E.coli (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 10 (TLR10)Toll-like receptor (TLR)Micebladder epithelial cellsextracellular domain containing leucine-rich repeats and an intracellular domain that contains a conserved region called the Toll/IL-1 receptor (TIR) domain and the trans membrane domainQ6R5P0.fastaQ6R5P0926Activate NF-KBNA277566042016Pubchem_assay
PRRID_1816NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 1 (TLR1)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1816NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 1 (TLR1)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1817NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1817NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1818NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 5 (TLR5)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1818NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 5 (TLR5)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1819NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 9 (TLR9)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1819NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 9 (TLR9)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1820NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 21 (TLR21)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1820NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 21 (TLR21)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1821NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 22 (TLR22)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1821NA

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A.hydrophilla(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalBacterial infection, immunostimulantMaToll-like receptor 22 (TLR22)Toll-like receptor (TLR)Megalobrama amblycephalaliver, spleen and head kidneyLRR domain, TM region and TIR domainNANANAActivate NF-KbqRT-PCR276393152016NA
PRRID_1822NA

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NANANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantPoC1ql3Pattern recognition receptor (PRR)NANAC1q-domainNANANAActivate NF-KBNA276012082016NA
PRRID_1822NA

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NANANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantPoC1ql3Pattern recognition receptor (PRR)NANAC1q-domainNANANAActivate NF-KBNA276012082016NA
PRRID_1823NA

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Vibrio vulnificus (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantrSsLec1C type Lectin (CTL/CLR)Sebastes schlegeliikidney, liver, spleen and macrophagescarbohydrate-recognition domain (CRD),NANANAActivate NF-KBMicrobial binding assay275699822016NA
PRRID_1823NA

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Vibrio vulnificus (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantrSsLec1C type Lectin (CTL/CLR)Sebastes schlegeliikidney, liver, spleen and macrophagescarbohydrate-recognition domain (CRD),NANANAActivate NF-KBMicrobial binding assay275699822016NA
PRRID_1824NA

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Vibrio ichthyoenteri (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantrSsLec1C type Lectin (CTL/CLR)Sebastes schlegeliiKidney, liver, spleen and macrophagesCarbohydrate recognition domain (CRD)NANANAActivate NF-KBMicrobial binding assay275699822016NA
PRRID_1824NA

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Vibrio ichthyoenteri (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantrSsLec1C type Lectin (CTL/CLR)Sebastes schlegeliiKidney, liver, spleen and macrophagesCarbohydrate recognition domain (CRD)NANANAActivate NF-KBMicrobial binding assay275699822016NA
PRRID_1825NA

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Gram positive bacteriaNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantApSPZSpatzleA. pernyifat body tissueno conserved domainsNANANAactivation and signaling of the Toll pathwayqRT-PCR274834632016NA
PRRID_1825NA

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Gram positive bacteriaNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantApSPZSpatzleA. pernyifat body tissueno conserved domainsNANANAactivation and signaling of the Toll pathwayqRT-PCR274834632016NA
PRRID_1826NA

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V. anguillarum (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantSmPGRP2Peptidoglycan Recognition Receptor (PGRPs)Scophthalmus maximus liver, spleen, and head-kidney,intestine, gill and skinNANANANAActivate NF-KBqRT-PCR274614222016NA
PRRID_1826NA

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V. anguillarum (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantSmPGRP2Peptidoglycan Recognition Receptor (PGRPs)Scophthalmus maximus liver, spleen, and head-kidney,intestine, gill and skinNANANANAActivate NF-KBqRT-PCR274614222016NA
PRRID_1827NA

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Streptococus agalactiae (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalCause bacterial infection, immunostimulantLjToll-like receptor (TLR 5MToll-like receptor (TLR)Lateolabrax japonicasspleen and head-kidneyLRRs (extracellular leucine rich repeats), transmembrane and TIR (Toll/interleukin-1 receptor) domain.NANANAActivate NF-KB, synergistic effect with other TLRs to defense the pathogenic bacteriaqRT-PCR274172332016NA
PRRID_1827NA

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Streptococus agalactiae (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalCause bacterial infection, immunostimulantLjToll-like receptor (TLR 5MToll-like receptor (TLR)Lateolabrax japonicasspleen and head-kidneyLRRs (extracellular leucine rich repeats), transmembrane and TIR (Toll/interleukin-1 receptor) domain.NANANAActivate NF-KB, synergistic effect with other TLRs to defense the pathogenic bacteriaqRT-PCR274172332016NA
PRRID_1828NA

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Vibrio harveyi (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalCause bacterial infection, immunostimulantLjToll-like receptor (TLR 5MToll-like receptor (TLR)Lateolabrax japonicasspleen and head-kidneyLRRs (extracellular leucine rich repeats), transmembrane and TIR (Toll/interleukin-1 receptor) domain.NANANAActivate NF-KBqRT-PCR274172332016NA
PRRID_1828NA

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Vibrio harveyi (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalCause bacterial infection, immunostimulantLjToll-like receptor (TLR 5MToll-like receptor (TLR)Lateolabrax japonicasspleen and head-kidneyLRRs (extracellular leucine rich repeats), transmembrane and TIR (Toll/interleukin-1 receptor) domain.NANANAActivate NF-KBqRT-PCR274172332016NA
PRRID_1829NA

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V. parahaemolyticus (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantCnToll-like receptor 1 (TLR-1)Toll-like receptor (TLR)Chlamys nobilismantle, he- mocytes, gill, kidney, gonad, hepatopancreasfive leucine-rich repeats (LRR), two LRR-C-terminal (LRRCT) motifs and a LRR-N-terminal (LRRNT) motif in the extracellular domain, a transmembrane domain and a Toll/Interleukin-1 Receptor (TIR) of 138NANANAbinds to microbes and act as PRR.qRT-PCR274035922016NA
PRRID_1829NA

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V. parahaemolyticus (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantCnToll-like receptor 1 (TLR-1)Toll-like receptor (TLR)Chlamys nobilismantle, he- mocytes, gill, kidney, gonad, hepatopancreasfive leucine-rich repeats (LRR), two LRR-C-terminal (LRRCT) motifs and a LRR-N-terminal (LRRNT) motif in the extracellular domain, a transmembrane domain and a Toll/Interleukin-1 Receptor (TIR) of 138NANANAbinds to microbes and act as PRR.qRT-PCR274035922016NA
PRRID_1831NA

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viral hemorrhagic septicemia (virus)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantEcToll-like receptor 2b (TLR2b)Toll-like receptor (TLR)ZebrafishGills and spleenleucine-rich repeat (LRR) domains (including an LRR-NT (except for EcTLR1b), several LRR motifs and an LRR-CT), a trans-membrane region and a Toll/interleukin-1 receptor (TIR) domain.NANANAActivate NF-KbNA270372192016NA
PRRID_1831NA

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viral hemorrhagic septicemia (virus)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantEcToll-like receptor 2b (TLR2b)Toll-like receptor (TLR)ZebrafishGills and spleenleucine-rich repeat (LRR) domains (including an LRR-NT (except for EcTLR1b), several LRR motifs and an LRR-CT), a trans-membrane region and a Toll/interleukin-1 receptor (TIR) domain.NANANAActivate NF-KbNA270372192016NA
PRRID_1832NA

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C. irritans (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantEcToll-like receptor 14 (TLR14)Toll-like receptor (TLR)ZebrafishGills and spleenleucine-rich repeat (LRR) domains (including an LRR-NT (except for EcTLR1b), several LRR motifs and an LRR-CT), a trans-membrane region and a Toll/interleukin-1 receptor (TIR) domain.NANANAActivate NF-KbNA270372192016NA
PRRID_1832NA

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C. irritans (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantEcToll-like receptor 14 (TLR14)Toll-like receptor (TLR)ZebrafishGills and spleenleucine-rich repeat (LRR) domains (including an LRR-NT (except for EcTLR1b), several LRR motifs and an LRR-CT), a trans-membrane region and a Toll/interleukin-1 receptor (TIR) domain.NANANAActivate NF-KbNA270372192016NA
PRRID_1834Nucleic acid

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H9N2(Avian influezna virus) (virus)NANAPattern-associated molecular patterns (PAMPs)NaturalCauses Avian influenza and act as immunostimulant for TLR.goToll-like receptor 7 (TLR7)Toll-like receptor (TLR)WaterfowllungsTIR domainNANANAProliferation of cytokines and activation of NF-kBqRT-PCR278329632016NA
PRRID_1834Nucleic acid

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H9N2(Avian influezna virus) (virus)NANAPattern-associated molecular patterns (PAMPs)NaturalCauses Avian influenza and act as immunostimulant for TLR.goToll-like receptor 7 (TLR7)Toll-like receptor (TLR)WaterfowllungsTIR domainNANANAProliferation of cytokines and activation of NF-kBqRT-PCR278329632016NA
PRRID_1835Nucleic acid

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Newcastle Disease Virus (virus)NANAPattern-associated molecular patterns (PAMPs)NaturalCauses Newcastle disease and act as immunostimulant for TLR.goToll-like receptor 21 (TLR21)Toll-like receptor (TLR)WaterfowlEndoplasmic recticulumTIR domainNANANAProliferation of cytokines and activation of NF-kBqRT-PCR278329632016NA
PRRID_1835Nucleic acid

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Newcastle Disease Virus (virus)NANAPattern-associated molecular patterns (PAMPs)NaturalCauses Newcastle disease and act as immunostimulant for TLR.goToll-like receptor 21 (TLR21)Toll-like receptor (TLR)WaterfowlEndoplasmic recticulumTIR domainNANANAProliferation of cytokines and activation of NF-kBqRT-PCR278329632016NA
PRRID_1836O-linked mannobiose-rich glycoprotein

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M. tuberculosis, S. enterica, S. mansoni, C. albicans, A. fumigatus, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-2C type Lectin (CTL/CLR)HumanNANAQ6EIG7.fastaQ6EIG7209Pathogen recognition; antigen uptakeNA279999922016Pubchem_assay
PRRID_1836O-linked mannobiose-rich glycoprotein

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M. tuberculosis, S. enterica, S. mansoni, C. albicans, A. fumigatus, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-2C type Lectin (CTL/CLR)HumanNANAQ6EIG7.fastaQ6EIG7209Pathogen recognition; antigen uptakeNA279999922016Pubchem_assay
PRRID_1837Pam3CSk4

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BacteriaCCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)ZebrafishPlasma membraneextracellular (or intra- endosomal) ligand-binding domain with a leucine-rich repeat (LRR) motif and a cytoplasmic signaling Toll/Interleukin-1 (IL-1) receptor homology (TIR) domainF1QWS9.fastaF1QWS9818induce IFN expressionNA277214562016Pubchem_assay
PRRID_1837Pam3CSk4

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BacteriaCCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)ZebrafishPlasma membraneextracellular (or intra- endosomal) ligand-binding domain with a leucine-rich repeat (LRR) motif and a cytoplasmic signaling Toll/Interleukin-1 (IL-1) receptor homology (TIR) domainF1QWS9.fastaF1QWS9818induce IFN expressionNA277214562016Pubchem_assay
PRRID_1854Proteases

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Fasciola hepatica (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Mice (Murine)NANAQ99MB1.fastaQ99MB1905Dampen TRIF signaling by degradation of TLR3ÔòªNA271202222016Pubchem_assay
PRRID_1854Proteases

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Fasciola hepatica (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Mice (Murine)NANAQ99MB1.fastaQ99MB1905Dampen TRIF signaling by degradation of TLR3ÔòªNA271202222016Pubchem_assay
PRRID_1855PS lipids

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784‚Üìp38NA271202222016Pubchem_assay
PRRID_1855PS lipids

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784‚Üìp38NA271202222016Pubchem_assay
PRRID_1856PS lipids

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Ascaris lumbricoides/small intestine (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784‚Üì p38NA271202222016Pubchem_assay
PRRID_1856PS lipids

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Ascaris lumbricoides/small intestine (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784‚Üì p38NA271202222016Pubchem_assay
PRRID_1857PS lipids

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784‚Üìp38NA271202222016Pubchem_assay
PRRID_1857PS lipids

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784‚Üìp38NA271202222016Pubchem_assay
PRRID_1858PS lipids

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Ascaris lumbricoides/small intestine (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784‚Üì p38NA271202222016Pubchem_assay
PRRID_1858PS lipids

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Ascaris lumbricoides/small intestine (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784‚Üì p38NA271202222016Pubchem_assay
PRRID_1859pseudocoelomic fluid (PCF)

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Ascaris suum/Intestine (pigs and human)(others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784Through either TLR2 or TLR4ÔòºNA271202222016Pubchem_assay
PRRID_1859pseudocoelomic fluid (PCF)

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Ascaris suum/Intestine (pigs and human)(others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784Through either TLR2 or TLR4ÔòºNA271202222016Pubchem_assay
PRRID_1860pseudocoelomic fluid (PCF)

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Ascaris suum/Intestine (pigs and human)(others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784TLR2-dependentNA271202222016Pubchem_assay
PRRID_1860pseudocoelomic fluid (PCF)

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Ascaris suum/Intestine (pigs and human)(others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784TLR2-dependentNA271202222016Pubchem_assay
PRRID_1862rAs-MIF

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Anisakis simplex/intestine (marine mammals, human)(others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784‚Üë Treg via TLR2 dependentNA271202222016Pubchem_assay
PRRID_1862rAs-MIF

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Anisakis simplex/intestine (marine mammals, human)(others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784‚Üë Treg via TLR2 dependentNA271202222016Pubchem_assay
PRRID_1863rAs-MIF

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Anisakis simplex/intestine (marine mammals, human)(others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784‚Üë Treg viaNA271202222016Pubchem_assay
PRRID_1863rAs-MIF

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Anisakis simplex/intestine (marine mammals, human)(others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784‚Üë Treg viaNA271202222016Pubchem_assay
PRRID_1864Resistin

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NANANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 4 (TLR4)Toll-like receptor (TLR)NANANANANANAActivate NF-KbNA272933182016NA
PRRID_1864Resistin

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NANANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 4 (TLR4)Toll-like receptor (TLR)NANANANANANAActivate NF-KbNA272933182016NA
PRRID_1865SEA

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784TLR2-dependent ERK signaling and retinoic acidNA271202222016Pubchem_assay
PRRID_1865SEA

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784TLR2-dependent ERK signaling and retinoic acidNA271202222016Pubchem_assay
PRRID_1866SEA

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784Through either TLR2 or TLR4NA271202222016Pubchem_assay
PRRID_1866SEA

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784Through either TLR2 or TLR4NA271202222016Pubchem_assay
PRRID_1868sialyl-Lex

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1868sialyl-Lex

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1869SJMHEÔõú

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784TLR2-dependent induction of cRAF signaling pathway TLRÔò∫-dependentNA271202222016Pubchem_assay
PRRID_1869SJMHEÔõú

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784TLR2-dependent induction of cRAF signaling pathway TLRÔò∫-dependentNA271202222016Pubchem_assay
PRRID_1870SJMHEÔõú

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Schistosoma japonicum (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784TLR2-dependent induction of cRAF signaling pathwayNA271202222016Pubchem_assay
PRRID_1870SJMHEÔõú

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Schistosoma japonicum (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784TLR2-dependent induction of cRAF signaling pathwayNA271202222016Pubchem_assay
PRRID_1871SM-16

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MicebloodNAQ9QUK6.fastaQ9QUK6835Inhibits degradation of the IRAK1 signalingNA271202222016Pubchem_assay
PRRID_1871SM-16

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S. mansoni (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MicebloodNAQ9QUK6.fastaQ9QUK6835Inhibits degradation of the IRAK1 signalingNA271202222016Pubchem_assay
PRRID_1872SMÔõú-16Ôòæ

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Helminths (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUK6.fastaQ9QUK6835Inhibits degradation of the IRAK1 signalingNA271202222016Pubchem_assay
PRRID_1872SMÔõú-16Ôòæ

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Helminths (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUK6.fastaQ9QUK6835Inhibits degradation of the IRAK1 signalingNA271202222016Pubchem_assay
PRRID_1873TcES

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Taenia crassiceps (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784TLR2Ôò∫-dependent induction of cRAF signaling pathway TLR2Ôò∫-dependentNA271202222016Pubchem_assay
PRRID_1873TcES

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Taenia crassiceps (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)NANAQ9QUN7.fastaQ9QUN7784TLR2Ôò∫-dependent induction of cRAF signaling pathway TLR2Ôò∫-dependentNA271202222016Pubchem_assay
PRRID_1874TcES

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Taenia crassiceps (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784TLR2-dependent ERK signaling and retinoic acidNA271202222016Pubchem_assay
PRRID_1874TcES

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Taenia crassiceps (others)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceNANAQ9QUN7.fastaQ9QUN7784TLR2-dependent ERK signaling and retinoic acidNA271202222016Pubchem_assay