Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0008 | Candida albicans Click for more detail | Candida albicans(fungi) | NA | NA | Whole cell | Natural | Candida albicans binds with human macrophage mannose receptor via carbohydrate recognition-like domains. | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | CRDs | P22897.fasta | P22897 | 1456 | It leads to the receptor-mediated endorytosis of mannose-rich glycoconjugate as well as phagocytosis as well as pinocytisisof yeasts. | Phagocytosis assay | 2258707 | 1990 | Pubchem Assay |
| PRRID_0008 | Candida albicans Click for more detail | Candida albicans(fungi) | NA | NA | Whole cell | Natural | Candida albicans binds with human macrophage mannose receptor via carbohydrate recognition-like domains. | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | CRDs | P22897.fasta | P22897 | 1456 | It leads to the receptor-mediated endorytosis of mannose-rich glycoconjugate as well as phagocytosis as well as pinocytisisof yeasts. | Phagocytosis assay | 2258707 | 1990 | Pubchem Assay |
| PRRID_0011 | D-mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0011 | D-mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0013 | L-fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0013 | L-fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0014 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0014 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0017 | TPA (tissue plasminogen activator) Click for more detail | Endogenous (others) | PERLQRVVTPVLARTDSEPSGLRGTHKPHRWGCRCGAHRAGARLVGTGMGPGESALGWAARMPPALFPPSHPFHFQRPRDIFKGKGKDREKCQAGLGSGPVGSSGRRGGLYHDGLELGLEVSLPGCWESPGGQEGCSRLREGQVQSPEWGRRWAAVWVVQPDWTEC | 166 | Protein | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0017 | TPA (tissue plasminogen activator) Click for more detail | Endogenous (others) | PERLQRVVTPVLARTDSEPSGLRGTHKPHRWGCRCGAHRAGARLVGTGMGPGESALGWAARMPPALFPPSHPFHFQRPRDIFKGKGKDREKCQAGLGSGPVGSSGRRGGLYHDGLELGLEVSLPGCWESPGGQEGCSRLREGQVQSPEWGRRWAAVWVVQPDWTEC | 166 | Protein | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0025 | Mannan Click for more detail | Fungi | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8416946 | 1993 | NA |
| PRRID_0025 | Mannan Click for more detail | Fungi | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8416946 | 1993 | NA |
| PRRID_0044 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | Carbohydrate moieties of SP-A enhanced adherence of Mycobacterium tuberculosis. | Mannose receptor | Mannose receptor (MR) | Human | Monocytes-derived macrophages | NA | P22897.fasta | P22897 | 1456 | Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis. | NA | 7594549 | 1995 | Pubchem Assay |
| PRRID_0044 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | Carbohydrate moieties of SP-A enhanced adherence of Mycobacterium tuberculosis. | Mannose receptor | Mannose receptor (MR) | Human | Monocytes-derived macrophages | NA | P22897.fasta | P22897 | 1456 | Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis. | NA | 7594549 | 1995 | Pubchem Assay |
| PRRID_0045 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | Carbohydrate moieties of SP-A enhanced adherence of Mycobacterium tuberculosis. | Mannose receptor | Mannose receptor (MR) | Human | Alveolar macrophages | NA | P22897.fasta | P22897 | 1456 | Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis. | NA | 7594549 | 1995 | Pubchem Assay |
| PRRID_0045 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | Carbohydrate moieties of SP-A enhanced adherence of Mycobacterium tuberculosis. | Mannose receptor | Mannose receptor (MR) | Human | Alveolar macrophages | NA | P22897.fasta | P22897 | 1456 | Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis. | NA | 7594549 | 1995 | Pubchem Assay |
| PRRID_0050 | lipo-arabinomannan Click for more detail | mycobacteria (Mycobacterium tuberculosis; Erdman strain) (Bacteria) | CCC(CO)NCCNC(CC)CO | NA | Glycolipid | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | NA | P22897.fasta | P22897 | 1456 | NA | Chromatographic analyses | 8906835 | 1996 | Pubchem Assay |
| PRRID_0050 | lipo-arabinomannan Click for more detail | mycobacteria (Mycobacterium tuberculosis; Erdman strain) (Bacteria) | CCC(CO)NCCNC(CC)CO | NA | Glycolipid | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | NA | P22897.fasta | P22897 | 1456 | NA | Chromatographic analyses | 8906835 | 1996 | Pubchem Assay |
| PRRID_0079 | Chondroitin Sulfates A Click for more detail | Host (Endogenous) (others) | CC(=O)NC1C(C(C(OC1O)CO)OS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0079 | Chondroitin Sulfates A Click for more detail | Host (Endogenous) (others) | CC(=O)NC1C(C(C(OC1O)CO)OS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0080 | Chondroitin Sulfates B Click for more detail | Host (Endogenous) (others) | NA | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0080 | Chondroitin Sulfates B Click for more detail | Host (Endogenous) (others) | NA | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0095 | Sulfated blood group chains Click for more detail | Host (Endogenous) (others) | NA | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0095 | Sulfated blood group chains Click for more detail | Host (Endogenous) (others) | NA | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0114 | alpha-methylmannoside Click for more detail | Bacteria | COC1C(C(C(C(O1)CO)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0114 | alpha-methylmannoside Click for more detail | Bacteria | COC1C(C(C(C(O1)CO)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0117 | Fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0117 | Fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0118 | glucose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0118 | glucose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0138 | Mannose Click for more detail | Fungi | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0138 | Mannose Click for more detail | Fungi | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0140 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0140 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0141 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0141 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0164 | Collagen Click for more detail | Host (Endogenous) (others) | MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM | 1464 | Protein | Natural | elicit innate immune response | Endo180 (Endocytic receptor 180) | Mannose receptor (MR) | Human | Endosomes | N-terminal cysteine-rich domain, a single fibronectin type II domain and eight C-type lectin- like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | Endo180 Functions in Cells as a Collagen Binding and Internalization Receptor | ELISA | 12972549 | 2003 | Pubchem Assay |
| PRRID_0164 | Collagen Click for more detail | Host (Endogenous) (others) | MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM | 1464 | Protein | Natural | elicit innate immune response | Endo180 (Endocytic receptor 180) | Mannose receptor (MR) | Human | Endosomes | N-terminal cysteine-rich domain, a single fibronectin type II domain and eight C-type lectin- like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | Endo180 Functions in Cells as a Collagen Binding and Internalization Receptor | ELISA | 12972549 | 2003 | Pubchem Assay |
| PRRID_0207 | Opacity protein Click for more detail | Neisseria meningitidis (Bacteria) | MNPAPKNLLFSSLLFSSLLFSSLLFSSAAQAASEDSSRSPYYVQADLAYAAERITHDYPKATGANNTSTVSDYFRNIRAHSIHPRVSVGYDFGDWRIAADYASYRKWNNNKYSVNTKEVSRNNSNGNDTWQELKTENQENGSFHAVSSLGLSAIYDFKLNDKFDKFKPYIGARVAYGHVKHQVHSVRKETTTVFSKPSGSATKPGQIPSLVTKPAYHESHSISSLGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEVSLGVRYRF | 273 | Protein | Natural | elicit innate immune response | Mannose-binding lectins | Mannose receptor (MR) | Human | NA | NA | B1PN75.fasta | B1PN75 | 38 | MBL binding to N. meningitidis and increases complement activation and killing of organisms. | ELISA | 15004183 | 2004 | Pubchem Assay |
| PRRID_0207 | Opacity protein Click for more detail | Neisseria meningitidis (Bacteria) | MNPAPKNLLFSSLLFSSLLFSSLLFSSAAQAASEDSSRSPYYVQADLAYAAERITHDYPKATGANNTSTVSDYFRNIRAHSIHPRVSVGYDFGDWRIAADYASYRKWNNNKYSVNTKEVSRNNSNGNDTWQELKTENQENGSFHAVSSLGLSAIYDFKLNDKFDKFKPYIGARVAYGHVKHQVHSVRKETTTVFSKPSGSATKPGQIPSLVTKPAYHESHSISSLGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEVSLGVRYRF | 273 | Protein | Natural | elicit innate immune response | Mannose-binding lectins | Mannose receptor (MR) | Human | NA | NA | B1PN75.fasta | B1PN75 | 38 | MBL binding to N. meningitidis and increases complement activation and killing of organisms. | ELISA | 15004183 | 2004 | Pubchem Assay |
| PRRID_0208 | Porins Click for more detail | Neisseria meningitidis (Bacteria) | MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF | 396 | Protein | Natural | elicit innate immune response | Mannose-binding lectins | Mannose receptor (MR) | Human | NA | NA | B1PN75.fasta | B1PN75 | 38 | MBL binding to N. meningitidis and increases complement activation and killing of organisms. | ELISA | 15004183 | 2004 | Pubchem Assay |
| PRRID_0208 | Porins Click for more detail | Neisseria meningitidis (Bacteria) | MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF | 396 | Protein | Natural | elicit innate immune response | Mannose-binding lectins | Mannose receptor (MR) | Human | NA | NA | B1PN75.fasta | B1PN75 | 38 | MBL binding to N. meningitidis and increases complement activation and killing of organisms. | ELISA | 15004183 | 2004 | Pubchem Assay |
| PRRID_0378 | Pseudomonas aeruginosa Click for more detail | Pseudomonas aeruginosa (Bacteria) | NA | NA | Whole organism | Natural | P. aeruginosa activates NF-kappaB and MAPK, leads to the producion of proinflammatory cytokines. | Mannose receptor | Mannose receptor (MR) | Human | Monocytes | NA | P22897.fasta | P22897 | 1456 | It has the role in the inflammation. | ELISA | 19197942 | 2009 | Pubchem Assay |
| PRRID_0378 | Pseudomonas aeruginosa Click for more detail | Pseudomonas aeruginosa (Bacteria) | NA | NA | Whole organism | Natural | P. aeruginosa activates NF-kappaB and MAPK, leads to the producion of proinflammatory cytokines. | Mannose receptor | Mannose receptor (MR) | Human | Monocytes | NA | P22897.fasta | P22897 | 1456 | It has the role in the inflammation. | ELISA | 19197942 | 2009 | Pubchem Assay |
| PRRID_0606 | lipo-arabinomannan Click for more detail | M. tuberculosis (Bacteria) | CCC(CO)NCCNC(CC)CO | NA | Glycolipid | Natural | Binding of ligand leads to the inhibition of phagolysosome maturation | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | It ensure its survival of M. toberculosis in the host | NA | 20488784 | 2010 | Pubchem Assay |
| PRRID_0606 | lipo-arabinomannan Click for more detail | M. tuberculosis (Bacteria) | CCC(CO)NCCNC(CC)CO | NA | Glycolipid | Natural | Binding of ligand leads to the inhibition of phagolysosome maturation | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | It ensure its survival of M. toberculosis in the host | NA | 20488784 | 2010 | Pubchem Assay |
| PRRID_0676 | mannose, fucose and N-acetylglucosamine residues Click for more detail | Endogenous (others) | C(C1C(C(C(C(O1)O)O)O)O)O, CC(C(C(C(C=O)O)O)O)O, CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | These ligands binds to MR in calcium-dependent fashion, leads to the secretion of proinflammatory molecules, resulted in inflammation | Mannose receptor | Mannose receptor (MR) | Mice (Murine) | macrophages, certain dendritic cells, endothelial cell and mesangial cells | NA | Q61830.fasta | Q61830 | 1456 | It helps in clearing endogenous ligands released in the inflammatory response including lysosomal hydrolases, tissue plasminogen activator and myeloperoxidase and also has tissue protection during inflammation | NA | 20650906 | 2010 | Pubchem Assay |
| PRRID_0676 | mannose, fucose and N-acetylglucosamine residues Click for more detail | Endogenous (others) | C(C1C(C(C(C(O1)O)O)O)O)O, CC(C(C(C(C=O)O)O)O)O, CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | These ligands binds to MR in calcium-dependent fashion, leads to the secretion of proinflammatory molecules, resulted in inflammation | Mannose receptor | Mannose receptor (MR) | Mice (Murine) | macrophages, certain dendritic cells, endothelial cell and mesangial cells | NA | Q61830.fasta | Q61830 | 1456 | It helps in clearing endogenous ligands released in the inflammatory response including lysosomal hydrolases, tissue plasminogen activator and myeloperoxidase and also has tissue protection during inflammation | NA | 20650906 | 2010 | Pubchem Assay |
| PRRID_1103 | Lipoteichoic Acid (LTA) Click for more detail | Streptococcus pyogenes (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | PPL is a glycoprotein with a lipoteichoic acid binding specificity and elicits the downstream cascade. | Philyra pisum lectin (PPL) | Mannose receptor (MR) | Philyra pisum | NA | NA | NA | NA | NA | It has antiproliferative effects on human cancer cells | Hemagglutination inhibition assay | 24381505 | 2013 | NA |
| PRRID_1103 | Lipoteichoic Acid (LTA) Click for more detail | Streptococcus pyogenes (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | PPL is a glycoprotein with a lipoteichoic acid binding specificity and elicits the downstream cascade. | Philyra pisum lectin (PPL) | Mannose receptor (MR) | Philyra pisum | NA | NA | NA | NA | NA | It has antiproliferative effects on human cancer cells | Hemagglutination inhibition assay | 24381505 | 2013 | NA |
| PRRID_1106 | Mannan Click for more detail | S. cerevisiae (Bacteria) | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O | NA | Polysaccharides | Natural | PPL is a glycoprotein with a mannan-binding specificity and elicits the downstream cascade. | Philyra pisum lectin (PPL) | Mannose receptor (MR) | Philyra pisum | NA | NA | NA | NA | NA | It has antiproliferative effects on human cancer cells | Hemagglutination inhibition assay | 24381505 | 2013 | NA |
| PRRID_1106 | Mannan Click for more detail | S. cerevisiae (Bacteria) | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O | NA | Polysaccharides | Natural | PPL is a glycoprotein with a mannan-binding specificity and elicits the downstream cascade. | Philyra pisum lectin (PPL) | Mannose receptor (MR) | Philyra pisum | NA | NA | NA | NA | NA | It has antiproliferative effects on human cancer cells | Hemagglutination inhibition assay | 24381505 | 2013 | NA |
| PRRID_1481 | Maltose-binding protein (MBP) Click for more detail | E. coli(Bacteria) | MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK | 396 | Pattern-associated molecular patterns (PAMPs) | Natural | responsible for the uptake and efficient catabolism of maltodextrins | Mannose Receptor (CD206) | Mannose receptor (MR) | Mice | peritoneal macrophages | cell surface | Q61830.fasta | Q61830 | 1456 | Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation | ELISA, Phagocytosis assay, Cytokine secretion assay, real-time PCR | 24825603 | 2014 | Pubchem_assay |
| PRRID_1481 | Maltose-binding protein (MBP) Click for more detail | E. coli(Bacteria) | MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK | 396 | Pattern-associated molecular patterns (PAMPs) | Natural | responsible for the uptake and efficient catabolism of maltodextrins | Mannose Receptor (CD206) | Mannose receptor (MR) | Mice | peritoneal macrophages | cell surface | Q61830.fasta | Q61830 | 1456 | Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation | ELISA, Phagocytosis assay, Cytokine secretion assay, real-time PCR | 24825603 | 2014 | Pubchem_assay |
| PRRID_1482 | Mannan Click for more detail | Fungi(Yeast) | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Polysaccharides | Natural | cell wall polysaccharide found in yeasts. | Mannose receptor | Mannose receptor (MR) | European and African Children | DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin) | NA | A5D8T8.fasta | A5D8T8 | 446 | Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation | ELISA | 24743542 | 2014 | Pubchem_assay |
| PRRID_1482 | Mannan Click for more detail | Fungi(Yeast) | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Polysaccharides | Natural | cell wall polysaccharide found in yeasts. | Mannose receptor | Mannose receptor (MR) | European and African Children | DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin) | NA | A5D8T8.fasta | A5D8T8 | 446 | Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation | ELISA | 24743542 | 2014 | Pubchem_assay |
| PRRID_1923 | App, MspA Click for more detail | NA | NA | NA | NA | Natural | In vivo virulence | Mannose receptor/CD206 (terminal mannose, GlcNAc, fucose) | Mannose receptor (MR) | NA | Cell surface | NA | NA | NA | NA | NA | NA | 28334203 | 2017 | NA |
| PRRID_1923 | App, MspA Click for more detail | NA | NA | NA | NA | Natural | In vivo virulence | Mannose receptor/CD206 (terminal mannose, GlcNAc, fucose) | Mannose receptor (MR) | NA | Cell surface | NA | NA | NA | NA | NA | NA | 28334203 | 2017 | NA |
| PRRID_2016 | endogenous glycoproteins Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Mannose Receptor 1 | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2016 | endogenous glycoproteins Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Mannose Receptor 1 | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2423 | NA Click for more detail | pathogenic viruses, bacteria, and fungi | NA | NA | NA | Natural | NA | MRC1 | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2423 | NA Click for more detail | pathogenic viruses, bacteria, and fungi | NA | NA | NA | Natural | NA | MRC1 | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2588 | repeated mannose units Click for more detail | NA | C(C1C(C(C(C(O1)O)O)O)O)O and CC(C(C(C(C=O)O)O)O)O | NA | Pattern-associated molecular patterns (PAMPs) | Natural | elicit innate immune response | Mannose Receptor 1 | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2588 | repeated mannose units Click for more detail | NA | C(C1C(C(C(C(O1)O)O)O)O)O and CC(C(C(C(C=O)O)O)O)O | NA | Pattern-associated molecular patterns (PAMPs) | Natural | elicit innate immune response | Mannose Receptor 1 | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |