Primary information |
---|
PRRID | PRRID_0676 |
Ligand Name | mannose, fucose and N-acetylglucosamine residues |
Source | Endogenous (others) |
Sequence of ligand | C(C1C(C(C(C(O1)O)O)O)O)O, CC(C(C(C(C=O)O)O)O)O, CC(=O)NC1C(C(C(OC1O)CO)O)O |
Length | NA |
Type | Damage-associated molecular patterns (DAMPs) |
Occurence | Natural |
Role of Ligand | These ligands binds to MR in calcium-dependent fashion, leads to the secretion of proinflammatory molecules, resulted in inflammation |
Name of receptor | Mannose receptor |
Type of receptor | Mannose receptor (MR) |
Source | Mice (Murine) |
Localization | macrophages, certain dendritic cells, endothelial cell and mesangial cells |
Domain | NA |
Sequence of Receptor | Q61830.fasta |
Swiss prot ID | Q61830 |
Length Of Receptor | 1456 |
Function | It helps in clearing endogenous ligands released in the inflammatory response including lysosomal hydrolases, tissue plasminogen activator and myeloperoxidase and also has tissue protection during inflammation |
Assay used | NA |
PMID | 20650906 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |
Primary information |
---|
PRRID | PRRID_0676 |
Ligand Name | mannose, fucose and N-acetylglucosamine residues |
Source | Endogenous (others) |
Sequence of ligand | C(C1C(C(C(C(O1)O)O)O)O)O, CC(C(C(C(C=O)O)O)O)O, CC(=O)NC1C(C(C(OC1O)CO)O)O |
Length | NA |
Type | Damage-associated molecular patterns (DAMPs) |
Occurence | Natural |
Role of Ligand | These ligands binds to MR in calcium-dependent fashion, leads to the secretion of proinflammatory molecules, resulted in inflammation |
Name of receptor | Mannose receptor |
Type of receptor | Mannose receptor (MR) |
Source | Mice (Murine) |
Localization | macrophages, certain dendritic cells, endothelial cell and mesangial cells |
Domain | NA |
Sequence of Receptor | Q61830.fasta |
Swiss prot ID | Q61830 |
Length Of Receptor | 1456 |
Function | It helps in clearing endogenous ligands released in the inflammatory response including lysosomal hydrolases, tissue plasminogen activator and myeloperoxidase and also has tissue protection during inflammation |
Assay used | NA |
PMID | 20650906 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |