Detailed description page of PRRDB2.0

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PRRID_0676 details
Primary information
PRRIDPRRID_0676
Ligand Namemannose, fucose and N-acetylglucosamine residues
SourceEndogenous (others)
Sequence of ligandC(C1C(C(C(C(O1)O)O)O)O)O, CC(C(C(C(C=O)O)O)O)O, CC(=O)NC1C(C(C(OC1O)CO)O)O
LengthNA
TypeDamage-associated molecular patterns (DAMPs)
OccurenceNatural
Role of LigandThese ligands binds to MR in calcium-dependent fashion, leads to the secretion of proinflammatory molecules, resulted in inflammation
Name of receptorMannose receptor
Type of receptorMannose receptor (MR)
Source Mice (Murine)
Localizationmacrophages, certain dendritic cells, endothelial cell and mesangial cells
DomainNA
Sequence of ReceptorQ61830.fasta
Swiss prot IDQ61830
Length Of Receptor1456
FunctionIt helps in clearing endogenous ligands released in the inflammatory response including lysosomal hydrolases, tissue plasminogen activator and myeloperoxidase and also has tissue protection during inflammation
Assay usedNA
PMID20650906
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0676
Ligand Namemannose, fucose and N-acetylglucosamine residues
SourceEndogenous (others)
Sequence of ligandC(C1C(C(C(C(O1)O)O)O)O)O, CC(C(C(C(C=O)O)O)O)O, CC(=O)NC1C(C(C(OC1O)CO)O)O
LengthNA
TypeDamage-associated molecular patterns (DAMPs)
OccurenceNatural
Role of LigandThese ligands binds to MR in calcium-dependent fashion, leads to the secretion of proinflammatory molecules, resulted in inflammation
Name of receptorMannose receptor
Type of receptorMannose receptor (MR)
Source Mice (Murine)
Localizationmacrophages, certain dendritic cells, endothelial cell and mesangial cells
DomainNA
Sequence of ReceptorQ61830.fasta
Swiss prot IDQ61830
Length Of Receptor1456
FunctionIt helps in clearing endogenous ligands released in the inflammatory response including lysosomal hydrolases, tissue plasminogen activator and myeloperoxidase and also has tissue protection during inflammation
Assay usedNA
PMID20650906
Year of Publication2010
Pubchem assayPubchem Assay