| Primary information |
|---|
| PRRID | PRRID_0676 |
| Ligand Name | mannose, fucose and N-acetylglucosamine residues |
| Source | Endogenous (others) |
| Sequence of ligand | C(C1C(C(C(C(O1)O)O)O)O)O, CC(C(C(C(C=O)O)O)O)O, CC(=O)NC1C(C(C(OC1O)CO)O)O |
| Length | NA |
| Type | Damage-associated molecular patterns (DAMPs) |
| Occurence | Natural |
| Role of Ligand | These ligands binds to MR in calcium-dependent fashion, leads to the secretion of proinflammatory molecules, resulted in inflammation |
| Name of receptor | Mannose receptor |
| Type of receptor | Mannose receptor (MR) |
| Source | Mice (Murine) |
| Localization | macrophages, certain dendritic cells, endothelial cell and mesangial cells |
| Domain | NA |
| Sequence of Receptor | Q61830.fasta |
| Swiss prot ID | Q61830 |
| Length Of Receptor | 1456 |
| Function | It helps in clearing endogenous ligands released in the inflammatory response including lysosomal hydrolases, tissue plasminogen activator and myeloperoxidase and also has tissue protection during inflammation |
| Assay used | NA |
| PMID | 20650906 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0676 |
| Ligand Name | mannose, fucose and N-acetylglucosamine residues |
| Source | Endogenous (others) |
| Sequence of ligand | C(C1C(C(C(C(O1)O)O)O)O)O, CC(C(C(C(C=O)O)O)O)O, CC(=O)NC1C(C(C(OC1O)CO)O)O |
| Length | NA |
| Type | Damage-associated molecular patterns (DAMPs) |
| Occurence | Natural |
| Role of Ligand | These ligands binds to MR in calcium-dependent fashion, leads to the secretion of proinflammatory molecules, resulted in inflammation |
| Name of receptor | Mannose receptor |
| Type of receptor | Mannose receptor (MR) |
| Source | Mice (Murine) |
| Localization | macrophages, certain dendritic cells, endothelial cell and mesangial cells |
| Domain | NA |
| Sequence of Receptor | Q61830.fasta |
| Swiss prot ID | Q61830 |
| Length Of Receptor | 1456 |
| Function | It helps in clearing endogenous ligands released in the inflammatory response including lysosomal hydrolases, tissue plasminogen activator and myeloperoxidase and also has tissue protection during inflammation |
| Assay used | NA |
| PMID | 20650906 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |