Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_0056Acetylated LDL

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Endogenous (others)CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1NALipoproteinNaturalImmunostimulantLectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)NAvascular endothelium and vascular-rich organs.NANANANANANA90527821997NA
PRRID_0056Acetylated LDL

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Endogenous (others)CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1NALipoproteinNaturalImmunostimulantLectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)NAvascular endothelium and vascular-rich organs.NANANANANANA90527821997NA
PRRID_0058Advanced Glycation End Products (AGE)

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Endogenous (others)NANAOthersNaturalImmunostimulantLectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)NAvascular endothelium and vascular-rich organs.NANANANANANA90527821997NA
PRRID_0058Advanced Glycation End Products (AGE)

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Endogenous (others)NANAOthersNaturalImmunostimulantLectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)NAvascular endothelium and vascular-rich organs.NANANANANANA90527821997NA
PRRID_0063oxidized LDL (OxLDL)

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Endogenous (others)CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1NALipoproteinNaturalImmunostimulantLectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)NAvascular endothelium and vascular-rich organs.NANANANANANA90527821997NA
PRRID_0063oxidized LDL (OxLDL)

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Endogenous (others)CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1NALipoproteinNaturalImmunostimulantLectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)NAvascular endothelium and vascular-rich organs.NANANANANANA90527821997NA
PRRID_0103Hypochlorite modified HDL

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Endogenous (others)CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)CNALipoproteinNaturalImmunostimulantLectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)NANANANANANAinduces pro-inflammatory cytokine responseNA112926792001NA
PRRID_0103Hypochlorite modified HDL

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Endogenous (others)CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)CNALipoproteinNaturalImmunostimulantLectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)NANANANANANAinduces pro-inflammatory cytokine responseNA112926792001NA
PRRID_0112Advanced Glycation End Products (AGE)

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Host (Endogenous) (others)NANAProteinNaturalAGE behaves as al ligand for BLOX-1.Lectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)HumanEndothelial cellsNAP78380.fastaP78380273Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products.Endocytic degradation assays118210702002Pubchem Assay
PRRID_0112Advanced Glycation End Products (AGE)

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Host (Endogenous) (others)NANAProteinNaturalAGE behaves as al ligand for BLOX-1.Lectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)HumanEndothelial cellsNAP78380.fastaP78380273Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products.Endocytic degradation assays118210702002Pubchem Assay
PRRID_0132Hypochlorite modified HDL

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Host (Endogenous) (others)CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)CNALipoproteinNaturalIt has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1).Lectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)Mice (Murine)CHO Cells—ldlA cellsNAQ9EQ09.fastaQ9EQ09363It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport.NA120701412002Pubchem Assay
PRRID_0132Hypochlorite modified HDL

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Host (Endogenous) (others)CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)CNALipoproteinNaturalIt has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1).Lectin-like oxidized LDLreceptor 1C type Lectin (CTL/CLR)Mice (Murine)CHO Cells—ldlA cellsNAQ9EQ09.fastaQ9EQ09363It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport.NA120701412002Pubchem Assay
PRRID_0169HCV E1 glycoproteins

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Hepatitis C Virus (virus)DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR106GlycoproteinNaturaltriggers immune responsesDC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)C type Lectin (CTL/CLR)Humandendritic cellsNANANANApromote HIV and Hepatitis C virus to infect T-cell from dendritic cellsenzyme-linked immunosorbent assay126343662003NA
PRRID_0169HCV E1 glycoproteins

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Hepatitis C Virus (virus)DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR106GlycoproteinNaturaltriggers immune responsesDC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)C type Lectin (CTL/CLR)Humandendritic cellsNANANANApromote HIV and Hepatitis C virus to infect T-cell from dendritic cellsenzyme-linked immunosorbent assay126343662003NA
PRRID_0170HCV E1 glycoproteins

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Hepatitis C Virus (virus)DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR106GlycoproteinNaturaltriggers immune responsesDC-SIGNR (Dendritic cell-specific ICAM-3-grabbing nonintegrin related protein)C type Lectin (CTL/CLR)Humanendothelial cell populations, including hepatic sinusoidal endothelial cellsNANANANAfunctions as an attachment factor for HIV and is expressed on liver sinusoidal endothelial cellsenzyme-linked immunosorbent assay126343662003NA
PRRID_0170HCV E1 glycoproteins

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Hepatitis C Virus (virus)DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR106GlycoproteinNaturaltriggers immune responsesDC-SIGNR (Dendritic cell-specific ICAM-3-grabbing nonintegrin related protein)C type Lectin (CTL/CLR)Humanendothelial cell populations, including hepatic sinusoidal endothelial cellsNANANANAfunctions as an attachment factor for HIV and is expressed on liver sinusoidal endothelial cellsenzyme-linked immunosorbent assay126343662003NA
PRRID_0171HCV E2 glycoproteins

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Hepatitis C Virus (virus)DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR106GlycoproteinNaturalelicit innate immune responseDC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)C type Lectin (CTL/CLR)Humandendritic cellsNANANANApromote HIV and Hepatitis C virus to infect T-cell from dendritic cellsenzyme-linked immunosorbent assay126343662003NA
PRRID_0171HCV E2 glycoproteins

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Hepatitis C Virus (virus)DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR106GlycoproteinNaturalelicit innate immune responseDC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)C type Lectin (CTL/CLR)Humandendritic cellsNANANANApromote HIV and Hepatitis C virus to infect T-cell from dendritic cellsenzyme-linked immunosorbent assay126343662003NA
PRRID_0172HCV E2 glycoproteins

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Hepatitis C Virus (virus)DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR106GlycoproteinNaturalelicit innate immune responseDC-SIGNR (Dendritic cell-specific ICAM-3-grabbing nonintegrin related protein)C type Lectin (CTL/CLR)Humanendothelial cell populations, including hepatic sinusoidal endothelial cellsNANANANAfunctions as an attachment factor for HIV and is expressed on liver sinusoidal endothelial cellsenzyme-linked immunosorbent assay126343662003NA
PRRID_0172HCV E2 glycoproteins

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Hepatitis C Virus (virus)DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR106GlycoproteinNaturalelicit innate immune responseDC-SIGNR (Dendritic cell-specific ICAM-3-grabbing nonintegrin related protein)C type Lectin (CTL/CLR)Humanendothelial cell populations, including hepatic sinusoidal endothelial cellsNANANANAfunctions as an attachment factor for HIV and is expressed on liver sinusoidal endothelial cellsenzyme-linked immunosorbent assay126343662003NA
PRRID_0174Lewis x

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H. pylori (Bacteria)CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)CO)O)NC(=O)C)O)O)ONACarbohydrateSyntheticIt strongly binds to the DC-SIGN.DC-SIGNC type Lectin (CTL/CLR)K562 cellsDendritic cellsLectin domainNANANAIt induces the pathogen-driven inflammatory responses.ELISA125743252003NA
PRRID_0174Lewis x

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H. pylori (Bacteria)CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)CO)O)NC(=O)C)O)O)ONACarbohydrateSyntheticIt strongly binds to the DC-SIGN.DC-SIGNC type Lectin (CTL/CLR)K562 cellsDendritic cellsLectin domainNANANAIt induces the pathogen-driven inflammatory responses.ELISA125743252003NA
PRRID_0175Lewis x

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S. mansoni (others)CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)CO)O)NC(=O)C)O)O)ONACarbohydrateSyntheticIt strongly binds to the DC-SIGN.DC-SIGNC type Lectin (CTL/CLR)K562 cellsDendritic cellsLectin domainNANANAIt induces the pathogen-driven inflammatory responses.ELISA125743252003NA
PRRID_0175Lewis x

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S. mansoni (others)CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)CO)O)NC(=O)C)O)O)ONACarbohydrateSyntheticIt strongly binds to the DC-SIGN.DC-SIGNC type Lectin (CTL/CLR)K562 cellsDendritic cellsLectin domainNANANAIt induces the pathogen-driven inflammatory responses.ELISA125743252003NA
PRRID_0176Lipopolysaccharide (LPS)

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H. pylori (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)SyntheticIt strongly binds to the DC-SIGN.DC-SIGNC type Lectin (CTL/CLR)K562 cellsDendritic cellsLectin domainNANANAIt induces the pathogen-driven inflammatory responses.ELISA125743252003NA
PRRID_0176Lipopolysaccharide (LPS)

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H. pylori (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)SyntheticIt strongly binds to the DC-SIGN.DC-SIGNC type Lectin (CTL/CLR)K562 cellsDendritic cellsLectin domainNANANAIt induces the pathogen-driven inflammatory responses.ELISA125743252003NA
PRRID_0179Mannose capped lipoarabinomannan

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Mycobacterium tuberculosis (Bacteria)C(C1C(C(C(C(O1)O)O)O)O)ONACarbohydrateSyntheticIt strongly binds to the DC-SIGN.DC-SIGNC type Lectin (CTL/CLR)K562 cellsDendritic cellsLectin domainNANANAIt induces the pathogen-driven inflammatory responses.ELISA125743252003NA
PRRID_0179Mannose capped lipoarabinomannan

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Mycobacterium tuberculosis (Bacteria)C(C1C(C(C(C(O1)O)O)O)O)ONACarbohydrateSyntheticIt strongly binds to the DC-SIGN.DC-SIGNC type Lectin (CTL/CLR)K562 cellsDendritic cellsLectin domainNANANAIt induces the pathogen-driven inflammatory responses.ELISA125743252003NA
PRRID_0189(man)3-ara

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Mycobacteria (Bacteria)NANACarbohydrateNaturalelicit innate immune responseDC-SIGNC type Lectin (CTL/CLR)THP-1 and K562NANANANANAIt inhibits the immuno-stimulatory function of dendritic cells.ELISA154811462004NA
PRRID_0189(man)3-ara

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Mycobacteria (Bacteria)NANACarbohydrateNaturalelicit innate immune responseDC-SIGNC type Lectin (CTL/CLR)THP-1 and K562NANANANANAIt inhibits the immuno-stimulatory function of dendritic cells.ELISA154811462004NA
PRRID_0190(man)3-ara

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Mycobacteria (Bacteria)NANACarbohydrateNaturalelicit innate immune responseDC-SIGNRC type Lectin (CTL/CLR)THP-1 and K562NANANANANAIt inhibits the immuno-stimulatory function of dendritic cells.ELISA154811462004NA
PRRID_0190(man)3-ara

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Mycobacteria (Bacteria)NANACarbohydrateNaturalelicit innate immune responseDC-SIGNRC type Lectin (CTL/CLR)THP-1 and K562NANANANANAIt inhibits the immuno-stimulatory function of dendritic cells.ELISA154811462004NA
PRRID_0191(man)3-ara

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Mycobacteria (Bacteria)NANACarbohydrateNaturalelicit innate immune responsemSIGN-R1C type Lectin (CTL/CLR)THP-1 and K562NANANANANAIt inhibits the immuno-stimulatory function of dendritic cells.ELISA154811462004NA
PRRID_0191(man)3-ara

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Mycobacteria (Bacteria)NANACarbohydrateNaturalelicit innate immune responsemSIGN-R1C type Lectin (CTL/CLR)THP-1 and K562NANANANANAIt inhibits the immuno-stimulatory function of dendritic cells.ELISA154811462004NA
PRRID_0194Conidia

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Aspergillus fumigatus(fungi)NANASporeNaturalIt exhibited phenotypic characteristics of mature DC, with increased CD86 and induced CD83 expression. It also exhibited the higher level og IL-10.DC-SIGNC type Lectin (CTL/CLR)HumanMacrophages and Dendritic cellsNANANANAIt mediates binding and internalization of Aspergillus fumigatus conidia.ELISA154945142004NA
PRRID_0194Conidia

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Aspergillus fumigatus(fungi)NANASporeNaturalIt exhibited phenotypic characteristics of mature DC, with increased CD86 and induced CD83 expression. It also exhibited the higher level og IL-10.DC-SIGNC type Lectin (CTL/CLR)HumanMacrophages and Dendritic cellsNANANANAIt mediates binding and internalization of Aspergillus fumigatus conidia.ELISA154945142004NA
PRRID_0201glycoprotein GP

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virus (Marburg virus)MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHTTSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHNFSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPTPSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG681GlycoproteinNaturalImmunostimulantDC-SIGNC type Lectin (CTL/CLR)HostNANANANANADCs are good candidates to modulate the immune system’s activity in infection, cancer, and autoimmunitysoluble S-based binding assay154798532004NA
PRRID_0201glycoprotein GP

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virus (Marburg virus)MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHTTSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHNFSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPTPSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG681GlycoproteinNaturalImmunostimulantDC-SIGNC type Lectin (CTL/CLR)HostNANANANANADCs are good candidates to modulate the immune system’s activity in infection, cancer, and autoimmunitysoluble S-based binding assay154798532004NA
PRRID_0202glycoprotein GP

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virus (Marburg virus)MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHTTSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHNFSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPTPSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG681GlycoproteinNaturalImmunostimulantDC-SIGNRC type Lectin (CTL/CLR)HostNANANANANADCs are good candidates to modulate the immune system’s activity in infection, cancer, and autoimmunitysoluble S-based binding assay154798532004NA
PRRID_0202glycoprotein GP

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virus (Marburg virus)MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHTTSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHNFSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPTPSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG681GlycoproteinNaturalImmunostimulantDC-SIGNRC type Lectin (CTL/CLR)HostNANANANANADCs are good candidates to modulate the immune system’s activity in infection, cancer, and autoimmunitysoluble S-based binding assay154798532004NA
PRRID_0209S protein

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virus (SARS-CoV)MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEI1255GlycoproteinNaturalImmunostimulantDC-SIGNC type Lectin (CTL/CLR)HostNANANANANADCs are good candidates to modulate the immune system’s activity in infection, cancer, and autoimmunitysoluble S-based binding assay154798532004NA
PRRID_0209S protein

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virus (SARS-CoV)MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEI1255GlycoproteinNaturalImmunostimulantDC-SIGNC type Lectin (CTL/CLR)HostNANANANANADCs are good candidates to modulate the immune system’s activity in infection, cancer, and autoimmunitysoluble S-based binding assay154798532004NA
PRRID_0215Soluble egg antigen (SEA)

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S. mansoni (others)MSGGKQHNAVSIPVNREQRSFEKQRRDLLTGLEHGGGAHRGNSIAPYTEDWPSTVDNWIDSSWKRWDDDMRRLRRGMFALLPLDTFSIGILENPFALMHQMDRQIQDIRERMGSLDVPSTGSVNDFLKDAYEVGEDGKVHFKVRFDAQGFAPQDINVTSSENRVTVHAKKETTTDGRKCSREFCRMVQLPKSIDDSQLKCRMTDDGVLMLEAPVKVDQNQSLTLNESGQVAVRPKSDNQIKAVPASQALVAKGVHGLSYVDDGSGGKRLHVEVAVDPVYKPEDLFVNVDSNRVVVSGRHHKQKSDQHGRSSSFAEFSQSYAIPETVDPLSVSAQVVGNTLVLEAPLEKQHAITH354OthersNaturalelicit innate immune responseL-SIGNC type Lectin (CTL/CLR)HumanLiver sinusoidal endothelial cellsNANANANANABinding assay151843722004NA
PRRID_0215Soluble egg antigen (SEA)

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S. mansoni (others)MSGGKQHNAVSIPVNREQRSFEKQRRDLLTGLEHGGGAHRGNSIAPYTEDWPSTVDNWIDSSWKRWDDDMRRLRRGMFALLPLDTFSIGILENPFALMHQMDRQIQDIRERMGSLDVPSTGSVNDFLKDAYEVGEDGKVHFKVRFDAQGFAPQDINVTSSENRVTVHAKKETTTDGRKCSREFCRMVQLPKSIDDSQLKCRMTDDGVLMLEAPVKVDQNQSLTLNESGQVAVRPKSDNQIKAVPASQALVAKGVHGLSYVDDGSGGKRLHVEVAVDPVYKPEDLFVNVDSNRVVVSGRHHKQKSDQHGRSSSFAEFSQSYAIPETVDPLSVSAQVVGNTLVLEAPLEKQHAITH354OthersNaturalelicit innate immune responseL-SIGNC type Lectin (CTL/CLR)HumanLiver sinusoidal endothelial cellsNANANANANABinding assay151843722004NA
PRRID_0216Soluble egg antigen (SEA)

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S. mansoni (others)MSGGKQHNAVSIPVNREQRSFEKQRRDLLTGLEHGGGAHRGNSIAPYTEDWPSTVDNWIDSSWKRWDDDMRRLRRGMFALLPLDTFSIGILENPFALMHQMDRQIQDIRERMGSLDVPSTGSVNDFLKDAYEVGEDGKVHFKVRFDAQGFAPQDINVTSSENRVTVHAKKETTTDGRKCSREFCRMVQLPKSIDDSQLKCRMTDDGVLMLEAPVKVDQNQSLTLNESGQVAVRPKSDNQIKAVPASQALVAKGVHGLSYVDDGSGGKRLHVEVAVDPVYKPEDLFVNVDSNRVVVSGRHHKQKSDQHGRSSSFAEFSQSYAIPETVDPLSVSAQVVGNTLVLEAPLEKQHAITH354OthersNaturalelicit innate immune responseDC-SIGNC type Lectin (CTL/CLR)HumanLiver sinusoidal endothelial cellsNANANANANABinding assay151843722004NA
PRRID_0216Soluble egg antigen (SEA)

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S. mansoni (others)MSGGKQHNAVSIPVNREQRSFEKQRRDLLTGLEHGGGAHRGNSIAPYTEDWPSTVDNWIDSSWKRWDDDMRRLRRGMFALLPLDTFSIGILENPFALMHQMDRQIQDIRERMGSLDVPSTGSVNDFLKDAYEVGEDGKVHFKVRFDAQGFAPQDINVTSSENRVTVHAKKETTTDGRKCSREFCRMVQLPKSIDDSQLKCRMTDDGVLMLEAPVKVDQNQSLTLNESGQVAVRPKSDNQIKAVPASQALVAKGVHGLSYVDDGSGGKRLHVEVAVDPVYKPEDLFVNVDSNRVVVSGRHHKQKSDQHGRSSSFAEFSQSYAIPETVDPLSVSAQVVGNTLVLEAPLEKQHAITH354OthersNaturalelicit innate immune responseDC-SIGNC type Lectin (CTL/CLR)HumanLiver sinusoidal endothelial cellsNANANANANABinding assay151843722004NA
PRRID_0242Heat-shock protein 70

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Host (Endogenous) (others)MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKIKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEAIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMRDKSENVQDLLLLDVAPLSLGPEAAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPMGASGSGPTIEEVD641ProteinNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)Chinese Hamsterovary cellsNANANANAPhagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammationHsp70 binding assay171427592006NA
PRRID_0242Heat-shock protein 70

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Host (Endogenous) (others)MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKIKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEAIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMRDKSENVQDLLLLDVAPLSLGPEAAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPMGASGSGPTIEEVD641ProteinNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)Chinese Hamsterovary cellsNANANANAPhagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammationHsp70 binding assay171427592006NA
PRRID_0262Pneumocystis carinii

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FungiNANAOthersNaturalImmunostimulantDectin-1C type Lectin (CTL/CLR)MiceMacrophagesNAQ6QLQ4.fastaQ6QLQ4244cytokine production NA171599822007Pubchem Assay
PRRID_0262Pneumocystis carinii

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FungiNANAOthersNaturalImmunostimulantDectin-1C type Lectin (CTL/CLR)MiceMacrophagesNAQ6QLQ4.fastaQ6QLQ4244cytokine production NA171599822007Pubchem Assay
PRRID_0273Carbohydrate moieties

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Candida albicans(fungi)NANACarbohydrateNaturalThe stimulation of mincle by carbohydrate moities, leads to the production of TNF-‚ç∫ by macrophages.MincleC type Lectin (CTL/CLR)MiceMacropahgesCarbohydrate binding motif (EPN)Q9R0Q8.fastaQ9R0Q8214Mincle plays a significant role in the mammalian immune response against the yeast.ELISA184907402008Pubchem Assay
PRRID_0273Carbohydrate moieties

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Candida albicans(fungi)NANACarbohydrateNaturalThe stimulation of mincle by carbohydrate moities, leads to the production of TNF-‚ç∫ by macrophages.MincleC type Lectin (CTL/CLR)MiceMacropahgesCarbohydrate binding motif (EPN)Q9R0Q8.fastaQ9R0Q8214Mincle plays a significant role in the mammalian immune response against the yeast.ELISA184907402008Pubchem Assay
PRRID_0280Curdlan

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Alcaligenes faecalis(Bacteria)C(C1C(C(C(C(O1)O)O)O)O)ONAGlucanNaturalCurdlan is a pure dectin-1 agonist and induces TNF-alpha production in human PBMCs and macrophages.Dectin-1C type Lectin (CTL/CLR)HumanPBMCs and monocyte-derived macrophages.NAQ9BXN2.fastaQ9BXN2247It is resoonsible for the immuno-inflammation in the host cell.ELISA185494572008Pubchem Assay
PRRID_0280Curdlan

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Alcaligenes faecalis(Bacteria)C(C1C(C(C(C(O1)O)O)O)O)ONAGlucanNaturalCurdlan is a pure dectin-1 agonist and induces TNF-alpha production in human PBMCs and macrophages.Dectin-1C type Lectin (CTL/CLR)HumanPBMCs and monocyte-derived macrophages.NAQ9BXN2.fastaQ9BXN2247It is resoonsible for the immuno-inflammation in the host cell.ELISA185494572008Pubchem Assay
PRRID_0461Dextran

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BacteriaC(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(C=O)O)O)O)O)O)O)O)O)O)O)ONACarbohydrateNaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0461Dextran

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BacteriaC(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(C=O)O)O)O)O)O)O)O)O)O)O)ONACarbohydrateNaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0549Heat-killed MTB

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Mycobacterium tuberculosis (Bacteria)NANAWhole organismNaturalIt induces the production of IL-17ADectin-1C type Lectin (CTL/CLR)HumanPBMCsNAQ9BXN2.fastaQ9BXN2247The immunoprophylactic role played by Ara-LAM in conferring protection against visceral leishmaniasisCytokines assay202996822010Pubchem Assay
PRRID_0549Heat-killed MTB

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Mycobacterium tuberculosis (Bacteria)NANAWhole organismNaturalIt induces the production of IL-17ADectin-1C type Lectin (CTL/CLR)HumanPBMCsNAQ9BXN2.fastaQ9BXN2247The immunoprophylactic role played by Ara-LAM in conferring protection against visceral leishmaniasisCytokines assay202996822010Pubchem Assay
PRRID_0558Histoplasma strain 505 yeast cells

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Histoplasma strain 506 (others)NANAWhole organismNaturalThe binding leads to the secretion of cytokines such as TNF-‚ç∫ and IL-6, via syk dependent pathwayDectin-1C type Lectin (CTL/CLR)Mice (Murine)Macropahgeslectin binding domainQ6QLQ4.fastaQ6QLQ4244It is was responsible for cytokine response.ELISA203604012010Pubchem Assay
PRRID_0558Histoplasma strain 505 yeast cells

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Histoplasma strain 506 (others)NANAWhole organismNaturalThe binding leads to the secretion of cytokines such as TNF-‚ç∫ and IL-6, via syk dependent pathwayDectin-1C type Lectin (CTL/CLR)Mice (Murine)Macropahgeslectin binding domainQ6QLQ4.fastaQ6QLQ4244It is was responsible for cytokine response.ELISA203604012010Pubchem Assay
PRRID_0643Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0643Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0659Lipoteichoic Acid (LTA)

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BacteriaC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)ONAAmphiphileNaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0659Lipoteichoic Acid (LTA)

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BacteriaC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)ONAAmphiphileNaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0673Mannan

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAPolysaccharidesNaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0673Mannan

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAPolysaccharidesNaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0674Mannose

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NAC(C1C(C(C(C(O1)O)O)O)O)ONACarbohydrateNaturalelicit innate immune responseMillectinC type Lectin (CTL/CLR)coral Acropora milleporanematocysts in epidermal tissueNANANANAMillectin expression is up-regulated in response to lipopolysaccharide and peptidoglycanimmunohistochemistry206002722010NA
PRRID_0674Mannose

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NAC(C1C(C(C(C(O1)O)O)O)O)ONACarbohydrateNaturalelicit innate immune responseMillectinC type Lectin (CTL/CLR)coral Acropora milleporanematocysts in epidermal tissueNANANANAMillectin expression is up-regulated in response to lipopolysaccharide and peptidoglycanimmunohistochemistry206002722010NA
PRRID_0741Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0741Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalIt is the responsive PAMP for the FcLec5FcLec5C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreasCRDNANANAIt elicit the immune response, which leads to the clearance of bacteriaELISA203493232010NA
PRRID_0806Sparan

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NANANABiological response modifiers (BRMs)Naturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)Candida albicansneutrophils, monocytes, and NK cellsNANANANANANA206991312010NA
PRRID_0806Sparan

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NANANABiological response modifiers (BRMs)Naturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)Candida albicansneutrophils, monocytes, and NK cellsNANANANANANA206991312010NA
PRRID_0807Sparan

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NANANABiological response modifiers (BRMs)Naturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)Aspergillus fumigatesneutrophils, monocytes, and NK cellsNANANANANANA206991312010NA
PRRID_0807Sparan

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NANANABiological response modifiers (BRMs)Naturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)Aspergillus fumigatesneutrophils, monocytes, and NK cellsNANANANANANA206991312010NA
PRRID_0808Sparan

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NANANABiological response modifiers (BRMs)Naturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)Pneumocystis cariniineutrophils, monocytes, and NK cellsNANANANANANA206991312010NA
PRRID_0808Sparan

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NANANABiological response modifiers (BRMs)Naturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)Pneumocystis cariniineutrophils, monocytes, and NK cellsNANANANANANA206991312010NA
PRRID_1092Lipopolysaccharide (LPS)

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E. coli Serotype 055:B5(Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responsePcLec5C type Lectin (CTL/CLR)red swamp crayfish (Procambarus clarkii)hepatopancreas, gills and intestinecarbohydrate recognition domain (CRD)NANANAplay important roles in the innate immune system of crustaceansELISA239890402013NA
PRRID_1092Lipopolysaccharide (LPS)

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E. coli Serotype 055:B5(Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responsePcLec5C type Lectin (CTL/CLR)red swamp crayfish (Procambarus clarkii)hepatopancreas, gills and intestinecarbohydrate recognition domain (CRD)NANANAplay important roles in the innate immune system of crustaceansELISA239890402013NA
PRRID_1102Lipoteichoic Acid (LTA)

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Staphylococcus staphylolyticus (Bacteria)C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)ONAAmphiphileNaturalelicit innate immune responsePcLec5C type Lectin (CTL/CLR)red swamp crayfish (Procambarus clarkii)hepatopancreas, gills and intestinecarbohydrate recognition domain (CRD)NANANAplay important roles in the innate immune system of crustaceansELISA239890402013NA
PRRID_1102Lipoteichoic Acid (LTA)

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Staphylococcus staphylolyticus (Bacteria)C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)ONAAmphiphileNaturalelicit innate immune responsePcLec5C type Lectin (CTL/CLR)red swamp crayfish (Procambarus clarkii)hepatopancreas, gills and intestinecarbohydrate recognition domain (CRD)NANANAplay important roles in the innate immune system of crustaceansELISA239890402013NA
PRRID_1117Peptidoglycan (PGN)

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Staphylococcus staphylolyticus (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalelicit innate immune responsePcLec5C type Lectin (CTL/CLR)red swamp crayfish (Procambarus clarkii)hepatopancreas, gills and intestinecarbohydrate recognition domain (CRD)NANANAplay important roles in the innate immune system of crustaceansELISA239890402013NA
PRRID_1117Peptidoglycan (PGN)

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Staphylococcus staphylolyticus (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalelicit innate immune responsePcLec5C type Lectin (CTL/CLR)red swamp crayfish (Procambarus clarkii)hepatopancreas, gills and intestinecarbohydrate recognition domain (CRD)NANANAplay important roles in the innate immune system of crustaceansELISA239890402013NA
PRRID_1227Curdlan

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BacteriaNANACarbohydrateSyntheticused in gel productionDectin-1C type Lectin (CTL/CLR)European and African ChildrenNANAQ9BXN2.fastaQ9BXN2247Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammationELISA247435422014Pubchem_assay
PRRID_1227Curdlan

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BacteriaNANACarbohydrateSyntheticused in gel productionDectin-1C type Lectin (CTL/CLR)European and African ChildrenNANAQ9BXN2.fastaQ9BXN2247Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammationELISA247435422014Pubchem_assay
PRRID_1500NA

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NANANANANaturalNADCIR2C type Lectin (CTL/CLR)MiceCD11c+CD82- DCsExogenousNANANADCs are good candidates to modulate the immune system’s activity in infection, cancer, and autoimmunityELISA248294112014NA
PRRID_1500NA

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NANANANANaturalNADCIR2C type Lectin (CTL/CLR)MiceCD11c+CD82- DCsExogenousNANANADCs are good candidates to modulate the immune system’s activity in infection, cancer, and autoimmunityELISA248294112014NA
PRRID_1700NA

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Gram negative Bacteria (Bacteria)NANANANaturalImmunostimulantHlCLecC type Lectin (CTL/CLR)Haemaphysalis longicornis ticks midgut and ovaryTriple carbohydrate recognition domainsNANANAKey role in innate immunity.NA267243792015NA
PRRID_1700NA

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Gram negative Bacteria (Bacteria)NANANANaturalImmunostimulantHlCLecC type Lectin (CTL/CLR)Haemaphysalis longicornis ticks midgut and ovaryTriple carbohydrate recognition domainsNANANAKey role in innate immunity.NA267243792015NA
PRRID_1742Fucose

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HIV-1 (virus)CC(C(C(C(C=O)O)O)O)ONACarbohydrateNaturalImmunostimulantDCIRC type Lectin (CTL/CLR)HumanNANANANANAInhibition of APC functions such as cytokine productionNA279999922016NA
PRRID_1742Fucose

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HIV-1 (virus)CC(C(C(C(C=O)O)O)O)ONACarbohydrateNaturalImmunostimulantDCIRC type Lectin (CTL/CLR)HumanNANANANANAInhibition of APC functions such as cytokine productionNA279999922016NA
PRRID_1743Fucose

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusCC(C(C(C(C=O)O)O)O)ONACarbohydrateNaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1743Fucose

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusCC(C(C(C(C=O)O)O)O)ONACarbohydrateNaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1747Gram-negative and Gram-positive bacteria

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NANANAProteinNaturalelicit innate immune responserMrLecC type Lectin (CTL/CLR)NANANANANANANANA269232442016NA
PRRID_1747Gram-negative and Gram-positive bacteria

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NANANAProteinNaturalelicit innate immune responserMrLecC type Lectin (CTL/CLR)NANANANANANANANA269232442016NA
PRRID_1752High-mannose and fucose glycans

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Mycobacterium spp., H. pylori, Lactobacillus spp., Leishmania spp., HIV-1, Dengue virus, Measles virNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDC-SIGNC type Lectin (CTL/CLR)HumanNANAQ9H2X3.fastaQ9H2X3399Pathogen recognition; Antigen uptake; APC/T cell interactions; Cell migrationNA279999922016Pubchem_assay
PRRID_1752High-mannose and fucose glycans

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Mycobacterium spp., H. pylori, Lactobacillus spp., Leishmania spp., HIV-1, Dengue virus, Measles virNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDC-SIGNC type Lectin (CTL/CLR)HumanNANAQ9H2X3.fastaQ9H2X3399Pathogen recognition; Antigen uptake; APC/T cell interactions; Cell migrationNA279999922016Pubchem_assay
PRRID_1753High-mannose glycans

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M. tuberculosis, S. enterica, S. mansoni, C. albicans, A. fumigatus, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-2C type Lectin (CTL/CLR)HumanNANAQ6EIG7.fastaQ6EIG7209Pathogen recognition; antigen uptakeNA279999922016Pubchem_assay
PRRID_1753High-mannose glycans

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M. tuberculosis, S. enterica, S. mansoni, C. albicans, A. fumigatus, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-2C type Lectin (CTL/CLR)HumanNANAQ6EIG7.fastaQ6EIG7209Pathogen recognition; antigen uptakeNA279999922016Pubchem_assay
PRRID_1756Lewis antigens

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Mycobacterium spp., H. pylori, Lactobacillus spp., Leishmania spp., HIV-1, Dengue virus, Measles virCC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)CO)O)NC(=O)C)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDC-SIGNC type Lectin (CTL/CLR)HumanNANAQ9H2X3.fastaQ9H2X3399Pathogen recognition; Antigen uptake; APC/T cell interactions; Cell migrationNA279999922016Pubchem_assay
PRRID_1756Lewis antigens

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Mycobacterium spp., H. pylori, Lactobacillus spp., Leishmania spp., HIV-1, Dengue virus, Measles virCC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)CO)O)NC(=O)C)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDC-SIGNC type Lectin (CTL/CLR)HumanNANAQ9H2X3.fastaQ9H2X3399Pathogen recognition; Antigen uptake; APC/T cell interactions; Cell migrationNA279999922016Pubchem_assay