Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_1643 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | triggers immune responses | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) | Q9QUK6.fasta | Q9QUK6 | 835 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1643 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | triggers immune responses | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) | Q9QUK6.fasta | Q9QUK6 | 835 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1644 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | triggers immune responses | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) | O00206.fasta | O00206 | 839 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1644 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | triggers immune responses | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) | O00206.fasta | O00206 | 839 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1646 | Tandem CARDs Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | cluster of differentiation 147 (CD147) | Pattern recognition receptor (PRR) | NA | NA | NA | NA | NA | NA | NA | NA | 25520185 | 2014 | NA |
| PRRID_1646 | Tandem CARDs Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | cluster of differentiation 147 (CD147) | Pattern recognition receptor (PRR) | NA | NA | NA | NA | NA | NA | NA | NA | 25520185 | 2014 | NA |
| PRRID_1649 | TgPRF (T. gondii profilin-like protein) Click for more detail | T. gondii (others) | MSDWDPVVKEWLVDTGYCCAGGIANVSAEDGVVFAAAADDDDGWSKLYKDDHEEDTIGEDGNACGKVSINEASTIKAAVDDGSAPNGVWIGGQKYKVVRPEKGFEYNDCTFDITMCARSKGGAHLIKTPNGSIVIALYDEEKEQDKGNSRTSALAFAEYLHQSGY | 165 | Protein | Natural | potently activate the innate immune system through its specific recognition by TLR11, which plays an important role in T. gondii infection in mice | Toll-like receptor 10 (TLR10) | Toll-like receptor (TLR) | Swiss albino mice brain | microglia/macrophages, astrocytes, and neurons | NA | Q6R5P0.fasta | Q6R5P0 | 926 | TLR11 activation is unique in its ability to initiate a parasite-specific innate immune response. TLR11 is unusual in its recognition of T. gondii, because it senses the pathogen by recognizing a profilin released by the microbe rather than by directly interacting with the live parasite | Double-labeling immunohistochemistry, Real-time quantitative polymerase chain reaction (PCR) | 24704432 | 2014 | Pubchem_assay |
| PRRID_1649 | TgPRF (T. gondii profilin-like protein) Click for more detail | T. gondii (others) | MSDWDPVVKEWLVDTGYCCAGGIANVSAEDGVVFAAAADDDDGWSKLYKDDHEEDTIGEDGNACGKVSINEASTIKAAVDDGSAPNGVWIGGQKYKVVRPEKGFEYNDCTFDITMCARSKGGAHLIKTPNGSIVIALYDEEKEQDKGNSRTSALAFAEYLHQSGY | 165 | Protein | Natural | potently activate the innate immune system through its specific recognition by TLR11, which plays an important role in T. gondii infection in mice | Toll-like receptor 10 (TLR10) | Toll-like receptor (TLR) | Swiss albino mice brain | microglia/macrophages, astrocytes, and neurons | NA | Q6R5P0.fasta | Q6R5P0 | 926 | TLR11 activation is unique in its ability to initiate a parasite-specific innate immune response. TLR11 is unusual in its recognition of T. gondii, because it senses the pathogen by recognizing a profilin released by the microbe rather than by directly interacting with the live parasite | Double-labeling immunohistochemistry, Real-time quantitative polymerase chain reaction (PCR) | 24704432 | 2014 | Pubchem_assay |
| PRRID_1657 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | S0F0X6.fasta | S0F0X6 | 1063 | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | Pubchem_assay |
| PRRID_1657 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | S0F0X6.fasta | S0F0X6 | 1063 | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | Pubchem_assay |
| PRRID_1658 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 8a1 (TLR8a1) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | NA | NA | NA | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | NA |
| PRRID_1658 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 8a1 (TLR8a1) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | NA | NA | NA | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | NA |
| PRRID_1659 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 8a2 (TLR8a2) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | S0F0N4.fasta | S0F0N4 | 1035 | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | Pubchem_assay |
| PRRID_1659 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 8a2 (TLR8a2) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | S0F0N4.fasta | S0F0N4 | 1035 | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | Pubchem_assay |
| PRRID_1660 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 8b1 (TLR8b1) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | S0F1A6.fasta | S0F1A6 | 1034 | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | Pubchem_assay |
| PRRID_1660 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 8b1 (TLR8b1) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | S0F1A6.fasta | S0F1A6 | 1034 | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | Pubchem_assay |
| PRRID_1661 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 8b2 (TLR8b2) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | S0F1D1.fasta | S0F1D1 | 1036 | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | Pubchem_assay |
| PRRID_1661 | type I interferons Click for more detail | Host (Endogenous) (others) | MYTVQSWTCICLIICSMQSVCHCCDWIRHHYGHLSSEYLSLLDQMGGDITKQDAPVFFPTSLYRHIDDAEVEDQVRFLKETIYQITKLFDGNMKSVTWDKKKLDDFLNILERQLENLKSCVSPAMKPEKRLKRYFKKLNKNVLRKMNYSAQAWELIRKETKRHLQRLDILAAQMY | 175 | Protein | Natural | induces TLR7 and TLR 8 in salmon | Toll-like receptor 8b2 (TLR8b2) | Toll-like receptor (TLR) | Atlantic salmon (Salmo salar) | highest expression in spleen and head kidney and relatively low expression in muscle, liver, gut, heart and gill | NA | S0F1D1.fasta | S0F1D1 | 1036 | antiviral response in salmon | Real-time PCR | 24736205 | 2014 | Pubchem_assay |
| PRRID_1702 | Surface Layer Proteins (SLPs) Click for more detail | Clostridium difficile(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Protein | Natural | The binding induces the production of IL-23 via MyD-88 signalling pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | Dendritic cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It has the role in the inflammation. | ELISA | 25626905 | 2015 | Pubchem_assay |
| PRRID_1702 | Surface Layer Proteins (SLPs) Click for more detail | Clostridium difficile(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Protein | Natural | The binding induces the production of IL-23 via MyD-88 signalling pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | Dendritic cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It has the role in the inflammation. | ELISA | 25626905 | 2015 | Pubchem_assay |
| PRRID_1703 | Surface Layer Proteins (SLPs) Click for more detail | Clostridium difficile(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Protein | Natural | The binding induces the production of IL-23 via MyD-88 signalling pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Dendritic cells | LRR | O00206.fasta | O00206 | 839 | It has the role in the inflammation. | ELISA | 25626905 | 2015 | Pubchem_assay |
| PRRID_1703 | Surface Layer Proteins (SLPs) Click for more detail | Clostridium difficile(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Protein | Natural | The binding induces the production of IL-23 via MyD-88 signalling pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Dendritic cells | LRR | O00206.fasta | O00206 | 839 | It has the role in the inflammation. | ELISA | 25626905 | 2015 | Pubchem_assay |
| PRRID_1737 | Flagellin Click for more detail | Salmonella (Bacteria) | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 10 (TLR10) | Toll-like receptor (TLR) | Mice | Plasma membrane | extracellular domain containing leucine-rich repeats and an intracellular domain that contains a conserved region called the Toll/IL-1 receptor (TIR) domain and the trans membrane domain | Q6R5P0.fasta | Q6R5P0 | 926 | Activate NF-KB | NA | 27756604 | 2016 | Pubchem_assay |
| PRRID_1737 | Flagellin Click for more detail | Salmonella (Bacteria) | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 10 (TLR10) | Toll-like receptor (TLR) | Mice | Plasma membrane | extracellular domain containing leucine-rich repeats and an intracellular domain that contains a conserved region called the Toll/IL-1 receptor (TIR) domain and the trans membrane domain | Q6R5P0.fasta | Q6R5P0 | 926 | Activate NF-KB | NA | 27756604 | 2016 | Pubchem_assay |
| PRRID_1738 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice | Plasma membrane | extracellular domain containing leucine-rich repeats and an intracellular domain that contains a conserved region called the Toll/IL-1 receptor (TIR) domain and the trans membrane domain | Q9JLF7.fasta | Q9JLF7 | 859 | nuclear factor NF- κB mobilization and the stimulation and secretion of cytokines. | NA | 27756604 | 2016 | Pubchem_assay |
| PRRID_1738 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice | Plasma membrane | extracellular domain containing leucine-rich repeats and an intracellular domain that contains a conserved region called the Toll/IL-1 receptor (TIR) domain and the trans membrane domain | Q9JLF7.fasta | Q9JLF7 | 859 | nuclear factor NF- κB mobilization and the stimulation and secretion of cytokines. | NA | 27756604 | 2016 | Pubchem_assay |
| PRRID_1739 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5a/b (TLR5a/b) | Toll-like receptor (TLR) | Zebrafish | endosomes and lysosomes. | extracellular (or intra- endosomal) ligand-binding domain with a leucine-rich repeat (LRR) motif and a cytoplasmic signaling Toll/Interleukin-1 (IL-1) receptor homology (TIR) domain | NA | NA | NA | induce IFN expression | NA | 27721456 | 2016 | NA |
| PRRID_1739 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5a/b (TLR5a/b) | Toll-like receptor (TLR) | Zebrafish | endosomes and lysosomes. | extracellular (or intra- endosomal) ligand-binding domain with a leucine-rich repeat (LRR) motif and a cytoplasmic signaling Toll/Interleukin-1 (IL-1) receptor homology (TIR) domain | NA | NA | NA | induce IFN expression | NA | 27721456 | 2016 | NA |
| PRRID_1740 | Flagellin Click for more detail | NA | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice (Murine) | NA | NA | Q9JLF7.fasta | Q9JLF7 | 859 | induce asthma | NA | 27120222 | 2016 | Pubchem_assay |
| PRRID_1740 | Flagellin Click for more detail | NA | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice (Murine) | NA | NA | Q9JLF7.fasta | Q9JLF7 | 859 | induce asthma | NA | 27120222 | 2016 | Pubchem_assay |
| PRRID_1747 | Gram-negative and Gram-positive bacteria Click for more detail | NA | NA | NA | Protein | Natural | elicit innate immune response | rMrLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26923244 | 2016 | NA |
| PRRID_1747 | Gram-negative and Gram-positive bacteria Click for more detail | NA | NA | NA | Protein | Natural | elicit innate immune response | rMrLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26923244 | 2016 | NA |
| PRRID_1791 | b-1, 3-glucans Click for more detail | Bacteria | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O | NA | Protein | Natural | elicit innate immune response | MnCTLDcp2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26208755 | 2016 | NA |
| PRRID_1791 | b-1, 3-glucans Click for more detail | Bacteria | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O | NA | Protein | Natural | elicit innate immune response | MnCTLDcp2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26208755 | 2016 | NA |
| PRRID_1796 | b-1, 3-glucans Click for more detail | Bacteria | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O | NA | Protein | Natural | elicit innate immune response | MnCTLDcp3 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26208755 | 2016 | NA |
| PRRID_1796 | b-1, 3-glucans Click for more detail | Bacteria | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O | NA | Protein | Natural | elicit innate immune response | MnCTLDcp3 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26208755 | 2016 | NA |
| PRRID_1830 | NA Click for more detail | NA | NA | NA | Protein | Natural | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 26958928 | 2016 | NA |
| PRRID_1830 | NA Click for more detail | NA | NA | NA | Protein | Natural | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 26958928 | 2016 | NA |
| PRRID_1838 | PAMPS Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | CfLRRop-1 | Leucine rich repeats (LRR) | NA | NA | NA | NA | NA | NA | NA | NA | 26385592 | 2016 | NA |
| PRRID_1838 | PAMPS Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | CfLRRop-1 | Leucine rich repeats (LRR) | NA | NA | NA | NA | NA | NA | NA | NA | 26385592 | 2016 | NA |
| PRRID_1845 | phenol-soluble modulin Click for more detail | S. aureus (Bacteria) | MEFVAKLFKFFKDLLGKFLGNN | 22 | Protein | Natural | Immunostimulant | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | Inhibit proinflammatory cytokines TNF, IL-12 and IL-6 | NA | 26775799 | 2016 | NA |
| PRRID_1845 | phenol-soluble modulin Click for more detail | S. aureus (Bacteria) | MEFVAKLFKFFKDLLGKFLGNN | 22 | Protein | Natural | Immunostimulant | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | Inhibit proinflammatory cytokines TNF, IL-12 and IL-6 | NA | 26775799 | 2016 | NA |
| PRRID_1887 | β -1,3-glucan Click for more detail | NA | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O | NA | Protein | Natural | NA | GRP2 | Gastrin-releasing peptide receptor (GRP) | NA | NA | NA | NA | NA | NA | NA | NA | 26504233 | 2016 | NA |
| PRRID_1887 | β -1,3-glucan Click for more detail | NA | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O | NA | Protein | Natural | NA | GRP2 | Gastrin-releasing peptide receptor (GRP) | NA | NA | NA | NA | NA | NA | NA | NA | 26504233 | 2016 | NA |
| PRRID_1917 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Rat | Hippocampus | NA | D9I2G4 .fasta | D9I2G4 | 1218 | NLRP1 inflammasome activation in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1917 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Rat | Hippocampus | NA | D9I2G4 .fasta | D9I2G4 | 1218 | NLRP1 inflammasome activation in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1918 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | hippocampus (neurons) | NA | Q9C000.fasta | Q9C000 | 1473 | protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1918 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | hippocampus (neurons) | NA | Q9C000.fasta | Q9C000 | 1473 | protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1919 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Mice | models of AD | NA | Q2LKU9.fasta | Q2LKU9 | 1182 | protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1919 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Mice | models of AD | NA | Q2LKU9.fasta | Q2LKU9 | 1182 | protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1920 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q2LKU9.fasta | Q2LKU9 | 1182 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1920 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q2LKU9.fasta | Q2LKU9 | 1182 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1921 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | Brain | NA | Q9C000.fasta | Q9C000 | 1473 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1921 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | Brain | NA | Q9C000.fasta | Q9C000 | 1473 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1922 | Anthrax lethal toxin Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | NALP3/ cryopyrin | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_1922 | Anthrax lethal toxin Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | NALP3/ cryopyrin | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_1945 | b-1,3-glucans. Click for more detail | Fungi | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O | NA | Protein | Natural | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 16S rRNA gene analysis | 29133884 | 2017 | NA |
| PRRID_1945 | b-1,3-glucans. Click for more detail | Fungi | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O | NA | Protein | Natural | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 16S rRNA gene analysis | 29133884 | 2017 | NA |
| PRRID_1987 | CpG motif Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | human peripheral B­lymphocytes | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 29170665 | 2017 | Pubchem_assay |
| PRRID_1987 | CpG motif Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | human peripheral B­lymphocytes | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 29170665 | 2017 | Pubchem_assay |
| PRRID_2035 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Human | NA | NA | O60602.fasta | O60602 | 858 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2035 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Human | NA | NA | O60602.fasta | O60602 | 858 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2036 | Flagellin Click for more detail | Gram negative bacteria(Leptospira spp.) | MIINHNLAAINSHRVLKFQNEEVSKNMEKLSSGMRINRAGDDASGLAVSEKMRTQVNGLRQAERNTEDGMSLIQTTEGFLQESNDIIQRIRTLAIQSSNGIYTDEDRQMIQVEVSQLIDEVDRIASQAEFNKMNLLQGDFARGSRATSMWFHLGPNMHQRERVFIATMTARALNLKGQSGDLLSLSTADKSNDAIGTLDAALTRISKQRANLGAYFNRLEHAAKGLMNAYENTQASESRIRDADMAEETVAFTKNQILVQSGTAMLAQANVRPQGVLSLLR | 281 | Protein | Natural | NA | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice | NA | Leucine-rich Repeat (LRR) Domain | Q9JLF7.fasta | Q9JLF7 | 859 | NA | NA | 29038956 | 2017 | Pubchem_assay |
| PRRID_2036 | Flagellin Click for more detail | Gram negative bacteria(Leptospira spp.) | MIINHNLAAINSHRVLKFQNEEVSKNMEKLSSGMRINRAGDDASGLAVSEKMRTQVNGLRQAERNTEDGMSLIQTTEGFLQESNDIIQRIRTLAIQSSNGIYTDEDRQMIQVEVSQLIDEVDRIASQAEFNKMNLLQGDFARGSRATSMWFHLGPNMHQRERVFIATMTARALNLKGQSGDLLSLSTADKSNDAIGTLDAALTRISKQRANLGAYFNRLEHAAKGLMNAYENTQASESRIRDADMAEETVAFTKNQILVQSGTAMLAQANVRPQGVLSLLR | 281 | Protein | Natural | NA | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice | NA | Leucine-rich Repeat (LRR) Domain | Q9JLF7.fasta | Q9JLF7 | 859 | NA | NA | 29038956 | 2017 | Pubchem_assay |
| PRRID_2037 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Induce secretion of cytokines, chemokines and co-stimulatory molecules from T cells | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O60602.fasta | O60602 | 858 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2037 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Induce secretion of cytokines, chemokines and co-stimulatory molecules from T cells | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O60602.fasta | O60602 | 858 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2038 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Bacterial infection | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Human | oral squamous cell carcinomas | Leucine-rich Repeat (LRR) Domain | O60602.fasta | O60602 | 858 | NA | NA | 28982847 | 2017 | Pubchem_assay |
| PRRID_2038 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Bacterial infection | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Human | oral squamous cell carcinomas | Leucine-rich Repeat (LRR) Domain | O60602.fasta | O60602 | 858 | NA | NA | 28982847 | 2017 | Pubchem_assay |
| PRRID_2039 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Innate immunity elicitor | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Human | Membrane | D0 domain | O60602.fasta | O60602 | 858 | recognizes a conserved region within the D1 domain of flagellin, crucial for the interaction between subunits in the flagellum and for bacterial motility. | Co-immunoprecipitataion Binding assay | 28827825 | 2017 | Pubchem_assay |
| PRRID_2039 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Innate immunity elicitor | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Human | Membrane | D0 domain | O60602.fasta | O60602 | 858 | recognizes a conserved region within the D1 domain of flagellin, crucial for the interaction between subunits in the flagellum and for bacterial motility. | Co-immunoprecipitataion Binding assay | 28827825 | 2017 | Pubchem_assay |
| PRRID_2040 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Innate immunity elicitor | NAIP5/NLRC4 inflammasome receptor | NOD-like receptor (NLR) | Human | intracellular | NA | NA | NA | NA | Recognizes flagellin and bind it. | Co-immunoprecipitataion Binding assay | 28827825 | 2017 | NA |
| PRRID_2040 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Innate immunity elicitor | NAIP5/NLRC4 inflammasome receptor | NOD-like receptor (NLR) | Human | intracellular | NA | NA | NA | NA | Recognizes flagellin and bind it. | Co-immunoprecipitataion Binding assay | 28827825 | 2017 | NA |
| PRRID_2041 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2041 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2042 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Nod-like receptor C4 (NLRC4) | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2042 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Nod-like receptor C4 (NLRC4) | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2043 | Flagellin Click for more detail | Vibrio (Bacteria) | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Leulectin | Pattern recognition receptor (PRR) | Marsupenaeus japonicus | Hemocytes | LRR | NA | NA | NA | Hemocytic Phagocytosis | Pull- down and far-Western assays | 28258197 | 2017 | NA |
| PRRID_2043 | Flagellin Click for more detail | Vibrio (Bacteria) | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Leulectin | Pattern recognition receptor (PRR) | Marsupenaeus japonicus | Hemocytes | LRR | NA | NA | NA | Hemocytic Phagocytosis | Pull- down and far-Western assays | 28258197 | 2017 | NA |
| PRRID_2044 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | EcToll-like receptor 5M (TLR5M) | Toll-like receptor (TLR) | Epinephelus coioides | Spleen | LRR domain, a transmembrane region and a TIR domain | NA | NA | NA | recognize flagellin and activate NF-κB, | qRT-PCR | 28159696 | 2017 | NA |
| PRRID_2044 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | EcToll-like receptor 5M (TLR5M) | Toll-like receptor (TLR) | Epinephelus coioides | Spleen | LRR domain, a transmembrane region and a TIR domain | NA | NA | NA | recognize flagellin and activate NF-κB, | qRT-PCR | 28159696 | 2017 | NA |
| PRRID_2045 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | EcToll-like receptor 5s (TLR5s) | Toll-like receptor (TLR) | Epinephelus coioides | Liver | LRR domain | NA | NA | NA | recognize flagellin and activate NF-κB, | qRT-PCR | 28159696 | 2017 | NA |
| PRRID_2045 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | EcToll-like receptor 5s (TLR5s) | Toll-like receptor (TLR) | Epinephelus coioides | Liver | LRR domain | NA | NA | NA | recognize flagellin and activate NF-κB, | qRT-PCR | 28159696 | 2017 | NA |
| PRRID_2046 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | OfToll-like receptor 5 (TLR5)M | Toll-like receptor (TLR) | Oplegnathus fasciatus | Liver | extracellular domain with 22 leucine rich repeats (LRR), a transmembrane domain and an 32 endodomain with TIR motif. | NA | NA | NA | responds to flagellin challenge and activates NF-κB | qRT-PCR | 28111358 | 2017 | NA |
| PRRID_2046 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | OfToll-like receptor 5 (TLR5)M | Toll-like receptor (TLR) | Oplegnathus fasciatus | Liver | extracellular domain with 22 leucine rich repeats (LRR), a transmembrane domain and an 32 endodomain with TIR motif. | NA | NA | NA | responds to flagellin challenge and activates NF-κB | qRT-PCR | 28111358 | 2017 | NA |
| PRRID_2047 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | IPAF | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2047 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | IPAF | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2048 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | NAIP | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2048 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | NAIP | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2049 | Flagellin (Legionella recognized) Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2049 | Flagellin (Legionella recognized) Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2162 | HMGB1 Click for more detail | nucleus, autophagosome (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | extracellular domain formed by three immunoglobulin domains (V-C1-C2), a single transmembrane domain and cytosolic portions. | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2162 | HMGB1 Click for more detail | nucleus, autophagosome (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | extracellular domain formed by three immunoglobulin domains (V-C1-C2), a single transmembrane domain and cytosolic portions. | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2163 | HMGB1 Click for more detail | nucleus, autophagosome (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | extracellular domain formed by three immunoglobulin domains (V-C1-C2), a single transmembrane domain and cytosolic portions. | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2163 | HMGB1 Click for more detail | nucleus, autophagosome (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | extracellular domain formed by three immunoglobulin domains (V-C1-C2), a single transmembrane domain and cytosolic portions. | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2164 | HMGB1 Click for more detail | nucleus, autophagosome (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | extracellular domain formed by three immunoglobulin domains (V-C1-C2), a single transmembrane domain and cytosolic portions. | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2164 | HMGB1 Click for more detail | nucleus, autophagosome (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | extracellular domain formed by three immunoglobulin domains (V-C1-C2), a single transmembrane domain and cytosolic portions. | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2165 | HMGB1 Click for more detail | nucleus, autophagosome (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | RAGE | Receptor for advanced glycation endproducts (RAGE) | NA | NA | extracellular domain formed by three immunoglobulin domains (V-C1-C2), a single transmembrane domain and cytosolic portions. | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2165 | HMGB1 Click for more detail | nucleus, autophagosome (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | RAGE | Receptor for advanced glycation endproducts (RAGE) | NA | NA | extracellular domain formed by three immunoglobulin domains (V-C1-C2), a single transmembrane domain and cytosolic portions. | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2166 | HMGB1 Click for more detail | Host (Endogenous) (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE | 215 | Protein | Natural | translocates to the cytoplasm and extracellular space during cell activation and death | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | gastric epithelial cells | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29146293 | 2017 | Pubchem_assay |
| PRRID_2166 | HMGB1 Click for more detail | Host (Endogenous) (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE | 215 | Protein | Natural | translocates to the cytoplasm and extracellular space during cell activation and death | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | gastric epithelial cells | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29146293 | 2017 | Pubchem_assay |