Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0035 | Advanced Glycation End Products (AGE) Click for more detail | NA | NA | NA | Protein | Natural | It leads to the formation of high molecular weight aggregates. | Galectin-3 | Pattern recognition receptor (PRR) | Rat | Macrophage-like RAW264.7 cells | NA | NA | NA | NA | It contributes to the elimination of pathogenic substances such as AGE. | Binding assay | 8529130 | 1995 | NA |
| PRRID_0035 | Advanced Glycation End Products (AGE) Click for more detail | NA | NA | NA | Protein | Natural | It leads to the formation of high molecular weight aggregates. | Galectin-3 | Pattern recognition receptor (PRR) | Rat | Macrophage-like RAW264.7 cells | NA | NA | NA | NA | It contributes to the elimination of pathogenic substances such as AGE. | Binding assay | 8529130 | 1995 | NA |
| PRRID_0049 | Fractionated [(3)H]heparin Click for more detail | Host (Endogenous) (others) | CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O | NA | Glycosaminoglycan | Natural | Fractionated [(3)H]heparin is a potent ligand for scavenger receptor A-I | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | Rat | Kupffer cells | NA | NA | NA | NA | Adsorptive endocytosis of polypeptides and phagocytosis. | NA | 8860963 | 1996 | NA |
| PRRID_0049 | Fractionated [(3)H]heparin Click for more detail | Host (Endogenous) (others) | CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O | NA | Glycosaminoglycan | Natural | Fractionated [(3)H]heparin is a potent ligand for scavenger receptor A-I | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | Rat | Kupffer cells | NA | NA | NA | NA | Adsorptive endocytosis of polypeptides and phagocytosis. | NA | 8860963 | 1996 | NA |
| PRRID_0309 | Lipopolysaccharide (LPS) Click for more detail | Escherichia coli (055:B5) (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | It leads to the activation of the transcription factor nuclear factor kappa B (NFKB) in caput and cauda epididymides. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | Epididymis | LRR | NA | NA | NA | Rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia coli through activation of Tolllike receptor 4. | EMSA | 18703421 | 2008 | NA |
| PRRID_0309 | Lipopolysaccharide (LPS) Click for more detail | Escherichia coli (055:B5) (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | It leads to the activation of the transcription factor nuclear factor kappa B (NFKB) in caput and cauda epididymides. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | Epididymis | LRR | NA | NA | NA | Rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia coli through activation of Tolllike receptor 4. | EMSA | 18703421 | 2008 | NA |
| PRRID_0562 | HMGB1 Click for more detail | Human (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | It interacts with the TLR4 and elicit immune response | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | Endothelial cells | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | It induced vascular endothelial activation | EMSA | 20714791 | 2010 | Pubchem Assay |
| PRRID_0562 | HMGB1 Click for more detail | Human (others) | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | It interacts with the TLR4 and elicit immune response | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | Endothelial cells | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | It induced vascular endothelial activation | EMSA | 20714791 | 2010 | Pubchem Assay |
| PRRID_0632 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | myocardium | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | NA | NA | 20697548 | 2010 | Pubchem Assay |
| PRRID_0632 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | myocardium | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | NA | NA | 20697548 | 2010 | Pubchem Assay |
| PRRID_0633 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | sCD14 | Pattern recognition receptor (PRR) | Rat | myocardium | NA | Q63691.fasta | Q63691 | 372 | NA | NF- | 20697548 | 2010 | Pubchem Assay |
| PRRID_0633 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | sCD14 | Pattern recognition receptor (PRR) | Rat | myocardium | NA | Q63691.fasta | Q63691 | 372 | NA | NF- | 20697548 | 2010 | Pubchem Assay |
| PRRID_0639 | Lipopolysaccharide (LPS) Click for more detail | Escherichia coli serotype 0127:B8 (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Binding of LPS trigger the NFKB pathway. | cluster of differentiation 14 (CD14) | Pattern recognition receptor (PRR) | Wistar Rat | Pineal gland (pinealocytes) | NA | Q63691.fasta | Q63691 | 372 | The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF and inhibiting melatonin synthesis | NA | 20586888 | 2010 | Pubchem Assay |
| PRRID_0639 | Lipopolysaccharide (LPS) Click for more detail | Escherichia coli serotype 0127:B8 (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Binding of LPS trigger the NFKB pathway. | cluster of differentiation 14 (CD14) | Pattern recognition receptor (PRR) | Wistar Rat | Pineal gland (pinealocytes) | NA | Q63691.fasta | Q63691 | 372 | The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF and inhibiting melatonin synthesis | NA | 20586888 | 2010 | Pubchem Assay |
| PRRID_0640 | Lipopolysaccharide (LPS) Click for more detail | Escherichia coli serotype 0127:B9 (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Binding of LPS trigger the NFKB pathway and inducing a local synthesis of the cytokine TNF, and the TNF receptor 1 (TNFR1) up-regulation in pinealocytes | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Wistar Rat | Pineal gland (pinealocytes) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF by inhibiting the NE-induced melatonin biosynthetic pathway and mount the inflammatory response | EMSA | 20586888 | 2010 | Pubchem Assay |
| PRRID_0640 | Lipopolysaccharide (LPS) Click for more detail | Escherichia coli serotype 0127:B9 (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Binding of LPS trigger the NFKB pathway and inducing a local synthesis of the cytokine TNF, and the TNF receptor 1 (TNFR1) up-regulation in pinealocytes | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Wistar Rat | Pineal gland (pinealocytes) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF by inhibiting the NE-induced melatonin biosynthetic pathway and mount the inflammatory response | EMSA | 20586888 | 2010 | Pubchem Assay |
| PRRID_0718 | OM-174 Click for more detail | E. coli(Bacteria) | CCCCCCCCCCC[C@@H](O)CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]2NC(=O)C[C@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@@H]1OP(O)(O)=O | NA | Lipid | Natural | it induce the expression of iNOS, tumour suppressive proteins and cytokines | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | Liver | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | It results into inhibition of invasion and metastasis of HCC | NA | 20675699 | 2010 | NA |
| PRRID_0718 | OM-174 Click for more detail | E. coli(Bacteria) | CCCCCCCCCCC[C@@H](O)CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]2NC(=O)C[C@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@@H]1OP(O)(O)=O | NA | Lipid | Natural | it induce the expression of iNOS, tumour suppressive proteins and cytokines | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | Liver | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | It results into inhibition of invasion and metastasis of HCC | NA | 20675699 | 2010 | NA |
| PRRID_1017 | V. vulnificus Click for more detail | Bacteria | NA | NA | NA | Natural | NA | LmGNBP3 | Gram-negative Bacteria-binding Protein (GNBPs) | Locusta migRatoria | NA | b-1,3-glu- canase-like domain | NA | NA | NA | NA | 16S rRNA gene analysis | 22062247 | 2012 | NA |
| PRRID_1017 | V. vulnificus Click for more detail | Bacteria | NA | NA | NA | Natural | NA | LmGNBP3 | Gram-negative Bacteria-binding Protein (GNBPs) | Locusta migRatoria | NA | b-1,3-glu- canase-like domain | NA | NA | NA | NA | 16S rRNA gene analysis | 22062247 | 2012 | NA |
| PRRID_1914 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1914 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1917 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Rat | Hippocampus | NA | D9I2G4 .fasta | D9I2G4 | 1218 | NLRP1 inflammasome activation in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1917 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Rat | Hippocampus | NA | D9I2G4 .fasta | D9I2G4 | 1218 | NLRP1 inflammasome activation in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1929 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1929 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2124 | Heat-shock protein 70 Click for more detail | NA | MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD | 641 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2124 | Heat-shock protein 70 Click for more detail | NA | MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD | 641 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2128 | Heat-shock protein 70 Click for more detail | NA | MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD | 641 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat hippocampus (microglia) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | mRNA ‚Üë in postoperative cognitive dysfunction in senile animals | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2128 | Heat-shock protein 70 Click for more detail | NA | MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD | 641 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat hippocampus (microglia) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | mRNA ‚Üë in postoperative cognitive dysfunction in senile animals | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2132 | Heat-shock protein 70 Click for more detail | NA | MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD | 641 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2132 | Heat-shock protein 70 Click for more detail | NA | MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD | 641 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2142 | Heat-shock proteins 60 Click for more detail | NA | MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2142 | Heat-shock proteins 60 Click for more detail | NA | MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2146 | Heat-shock proteins 60 Click for more detail | NA | MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat hippocampus (microglia) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | mRNA ‚Üë in postoperative cognitive dysfunction in senile animals | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2146 | Heat-shock proteins 60 Click for more detail | NA | MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat hippocampus (microglia) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | mRNA ‚Üë in postoperative cognitive dysfunction in senile animals | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2150 | Heat-shock proteins 60 Click for more detail | NA | MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2150 | Heat-shock proteins 60 Click for more detail | NA | MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2188 | HMGB1 Click for more detail | NA | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2188 | HMGB1 Click for more detail | NA | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2192 | HMGB1 Click for more detail | NA | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat hippocampus (microglia) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | mRNA ‚Üë in postoperative cognitive dysfunction in senile animals | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2192 | HMGB1 Click for more detail | NA | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat hippocampus (microglia) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | mRNA ‚Üë in postoperative cognitive dysfunction in senile animals | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2196 | HMGB1 Click for more detail | NA | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2196 | HMGB1 Click for more detail | NA | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE | 215 | Protein | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2261 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2261 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2292 | Lipoprotein Click for more detail | Bacteria | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | hippocampus (microglia) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | mRNA ‚Üë in postoperative cognitive dysfunction in senile animals | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2292 | Lipoprotein Click for more detail | Bacteria | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | hippocampus (microglia) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | mRNA ‚Üë in postoperative cognitive dysfunction in senile animals | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2295 | Lipoprotein Click for more detail | Bacteria | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2295 | Lipoprotein Click for more detail | Bacteria | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q6YGU2.fasta | Q6YGU2 | 784 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2333 | MDP (muramyldipeptide) Click for more detail | Gram-negative and Gram-positive bacteria | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C | NA | Peptide | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Rat | Hippocampus | NA | D9I2G4 .fasta | D9I2G4 | 1218 | NLRP1 inflammasome activation in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2333 | MDP (muramyldipeptide) Click for more detail | Gram-negative and Gram-positive bacteria | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C | NA | Peptide | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Rat | Hippocampus | NA | D9I2G4 .fasta | D9I2G4 | 1218 | NLRP1 inflammasome activation in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2341 | MDP (muramyldipeptide) Click for more detail | Gram-negative and Gram-positive bacteria | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C | NA | Peptide | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | NA | NA | NA | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | NA |
| PRRID_2341 | MDP (muramyldipeptide) Click for more detail | Gram-negative and Gram-positive bacteria | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C | NA | Peptide | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | NA | NA | NA | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | NA |
| PRRID_2438 | NA Click for more detail | S. cerevisiae (Bacteria) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | elicit innate immune response | CREP4 | C type Lectin (CTL/CLR) | B. glabRata | NA | NA | NA | NA | NA | NA | transcriptomic data | 29051762 | 2017 | NA |
| PRRID_2438 | NA Click for more detail | S. cerevisiae (Bacteria) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | elicit innate immune response | CREP4 | C type Lectin (CTL/CLR) | B. glabRata | NA | NA | NA | NA | NA | NA | transcriptomic data | 29051762 | 2017 | NA |
| PRRID_2446 | NA Click for more detail | S. mansoni (others) | NA | NA | Protein | Natural | NA | α-amylases | enzymes interacting with pathogens (EIP) | B. glabRata | NA | NA | NA | NA | NA | NA | NA | 29051762 | 2017 | NA |
| PRRID_2446 | NA Click for more detail | S. mansoni (others) | NA | NA | Protein | Natural | NA | α-amylases | enzymes interacting with pathogens (EIP) | B. glabRata | NA | NA | NA | NA | NA | NA | NA | 29051762 | 2017 | NA |
| PRRID_2502 | Nigericin Click for more detail | NA | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2502 | Nigericin Click for more detail | NA | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2598 | ROS Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2598 | ROS Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2674 | Uric acid Click for more detail | NA | C12=C(NC(=O)N1)NC(=O)NC2=O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the synthesis of IL-1β, TNF-α and TGF-β by murine macrophages. | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2674 | Uric acid Click for more detail | NA | C12=C(NC(=O)N1)NC(=O)NC2=O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the synthesis of IL-1β, TNF-α and TGF-β by murine macrophages. | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |