Browse By Cell Line Result Page of OvirusTdb
The total number of records retrieved from this search are 148. Click on ID to see further detail.
IDOV_606 | Virus nameAdenovirus | Virus strainCRAd-CCL21-IL15 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeIL-15 | Source of cell lineKey Laboratory of Zoonosis, Jilin University | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27380620 |
IDOV_609 | Virus nameAdenovirus | Virus strainCRAd-CCL21-IL15 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeIL-15 | Source of cell lineKey Laboratory of Zoonosis, Jilin University | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result40% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27380620 |
IDOV_612 | Virus nameAdenovirus | Virus strainCRAd-CCL21-IL15 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeIL-15 | Source of cell lineKey Laboratory of Zoonosis, Jilin University | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result18% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27380620 |
IDOV_615 | Virus nameAdenovirus | Virus strainCRAd-CCL21-IL15 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeIL-15 | Source of cell lineKey Laboratory of Zoonosis, Jilin University | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration50 MOI | In-vitro result10% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27380620 |
IDOV_717 | Virus nameAvian influenza A virus | Virus strainH7N3 NS1-77 | Virus genome typeRNA | Virus familyOrthomyxoviridae | Virus genome modificationMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77) | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayImmunoassay detection | In-vitro virus concentration0.001 MOI | In-vitro result130% cancer cell death (calculated as relative to mock-infected) | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUp-regulation of IFN-aplha | Clinical trialNA | PMID27417501 |
IDOV_721 | Virus nameAvian influenza A virus | Virus strainH7N3 | Virus genome typeRNA | Virus familyOrthomyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayImmunoassay detection | In-vitro virus concentration0.001 MOI | In-vitro result148% cancer cell death (calculated as relative to mock-infected) | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUp-regulation of IFN-aplha | Clinical trialNA | PMID27417501 |
IDOV_898 | Virus nameHerpes simplex virus | Virus strainBaco-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNon- fusogenic ligated with EGFP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result2% cancer cell killing after 24 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_899 | Virus nameHerpes simplex virus | Virus strainSynco-2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationFusogenic membrane ligated with GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result20% cancer cell killing after 24 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_900 | Virus nameHerpes simplex virus | Virus strainSynco-2D | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDouble fusogenic expressing EGFP and GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result50% cancer cell killing after 24 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_901 | Virus nameHerpes simplex virus | Virus strainBaco-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNon- fusogenic ligated with EGFP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result20% cancer cell killing after 48 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_902 | Virus nameHerpes simplex virus | Virus strainSynco-2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationFusogenic membrane ligated with GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result40% cancer cell killing after 48 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_903 | Virus nameHerpes simplex virus | Virus strainSynco-2D | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDouble fusogenic expressing EGFP and GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result80% cancer cell killing after 48 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_904 | Virus nameHerpes simplex virus | Virus strainBaco-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNon- fusogenic ligated with EGFP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result60% cancer cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_905 | Virus nameHerpes simplex virus | Virus strainSynco-2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationFusogenic membrane ligated with GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result80% cancer cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_906 | Virus nameHerpes simplex virus | Virus strainSynco-2D | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDouble fusogenic expressing EGFP and GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.01 pfu/cell | In-vitro result90% cancer cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_907 | Virus nameHerpes simplex virus | Virus strainBaco-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNon- fusogenic ligated with EGFP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result20% cancer cell killing after 24 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_908 | Virus nameHerpes simplex virus | Virus strainSynco-2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationFusogenic membrane ligated with GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result30% cancer cell killing after 24 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_909 | Virus nameHerpes simplex virus | Virus strainSynco-2D | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDouble fusogenic expressing EGFP and GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result50% cancer cell killing after 24 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_910 | Virus nameHerpes simplex virus | Virus strainBaco-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNon- fusogenic ligated with EGFP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result50% cancer cell killing after 48 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_911 | Virus nameHerpes simplex virus | Virus strainSynco-2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationFusogenic membrane ligated with GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result60% cancer cell killing after 48 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_912 | Virus nameHerpes simplex virus | Virus strainSynco-2D | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDouble fusogenic expressing EGFP and GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result100% cancer cell killing after 48 hour | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_913 | Virus nameHerpes simplex virus | Virus strainBaco-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNon- fusogenic ligated with EGFP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result60% cancer cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_914 | Virus nameHerpes simplex virus | Virus strainSynco-2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationFusogenic membrane ligated with GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result80% cancer cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_915 | Virus nameHerpes simplex virus | Virus strainSynco-2D | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDouble fusogenic expressing EGFP and GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3M-Pro4 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining | In-vitro virus concentration0.1 pfu/cell | In-vitro result100% cancer cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_1261 | Virus nameAdenovirus | Virus strainAxdAdb-3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDouble mutated for E1A and E1B gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell linePC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicity | AssayMTT assay | In-vitro virus concentration30 MOI | In-vitro resultSurviving cell number reached to 10000 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18063085 |
IDOV_1290 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration0.1 MOI | In-vitro result98% cell viability after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1291 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration0.1 MOI | In-vitro result90% cell viability after day 2 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1292 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration0.1 MOI | In-vitro result100% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1293 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration0.1 MOI | In-vitro result98% cell viability after day 4 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1294 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration1 MOI | In-vitro result98% cell viability after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1295 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration1 MOI | In-vitro result80% cell viability after day 2 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1296 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration1 MOI | In-vitro result70% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1297 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration1 MOI | In-vitro result60% cell viability after day 4 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1298 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration10 MOI | In-vitro result60% cell viability after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1299 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after day 2 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1300 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration10 MOI | In-vitro result30% cell viability afterd ay 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1301 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after day 4 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1408 | Virus nameParovirus | Virus strainH-1PV | Virus genome typeDNA | Virus familyParoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with norfloxacin (25 microgram/ml) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis, activation of caspase 3 | Immunogenic effectNA | Clinical trialNA | PMID19301953 |
IDOV_1409 | Virus nameParovirus | Virus strainH-1PV | Virus genome typeDNA | Virus familyParoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with norfloxacin (25 microgram/ml) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis, activation of caspase 3 | Immunogenic effectNA | Clinical trialNA | PMID19301953 |
IDOV_2014 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2015 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result30% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2016 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration10 MOI | In-vitro result10% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2017 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration100 MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2026 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (7.5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.125 MOI | In-vitro result80% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2027 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.25 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2028 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (30 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.5 MOI | In-vitro result60% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2029 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (60 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2030 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (120 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration2 MOI | In-vitro result40% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2278 | Virus nameVesicular stomatitis virus | Virus strainwild type | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2292 | Virus nameVesicular stomatitis virus | Virus strainVSV-Delta-M51-GFP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationDeletion of M51 gene and insertion of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2306 | Virus nameVesicular stomatitis virus | Virus strainVSV-p1-GFP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationInsertion of P gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2320 | Virus nameVesicular stomatitis virus | Virus strainSev-GFP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationInsertion of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2334 | Virus nameVesicular stomatitis virus | Virus strainRSV-GFP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationInsertion of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2348 | Virus nameVesicular stomatitis virus | Virus strainwild type | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2362 | Virus nameVesicular stomatitis virus | Virus strainVSV-Delta-M51-GFP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationDeletion of M51 gene and insertion of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2376 | Virus nameVesicular stomatitis virus | Virus strainVSV-p1-GFP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationInsertion of P gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2390 | Virus nameVesicular stomatitis virus | Virus strainSev-GFP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationVirus expressing GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_2404 | Virus nameVesicular stomatitis virus | Virus strainRSV-GFP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationVirus expressing GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell linePancreatic ductal adeonocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line80% confluent monolayer | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectDownregulation of IFN-Gamma | Clinical trialNA | PMID22238308 |
IDOV_3404 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.001 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3405 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.005 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3406 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3407 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.05 MOI | In-vitro result35% cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3408 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3424 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (2 × 10â»Â² micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result75% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3425 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (2 × 10â»Â² micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result75% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3432 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (1 × 10â»Â² micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result25% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3433 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (1 × 10â»Â² micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result50% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3440 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result70% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3441 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.03 MOI | In-vitro result60% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3442 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.05 MOI | In-vitro result52% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3443 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.01 MOI | In-vitro result50% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3444 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.03 MOI | In-vitro result40% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3445 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.05 MOI | In-vitro result30% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3538 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result90% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3539 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result80% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3540 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3541 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration20 MOI | In-vitro result58% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3542 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3543 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3544 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3545 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration20 MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3619 | Virus nameMeasles virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3620 | Virus nameMeasles virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result20% cell viability after day 6 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3633 | Virus nameMumps virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3634 | Virus nameMumps virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result10% cell viability after day 6 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3647 | Virus nameMeasles and mumps virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationMeasles virus in combination with mumps virus | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3648 | Virus nameMeasles and mumps virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationMeasles virus in combination with mumps virus | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result12% cell viability after day 6 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3723 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayAbsorbance measurements | In-vitro virus concentration0.1 MOI | In-vitro result15% cell viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryVirus induce apoptosis in cancer cell | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |
IDOV_3724 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M-Luc | Concentration of cell lineNA | In-vitro toxicityNA | AssayAbsorbance measurements | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryVirus induce apoptosis in cancer cell | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |
IDOV_3730 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayAbsorbance measurements | In-vitro virus concentration10 MOI | In-vitro result15% cell viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryVirus induce apoptosis in cancer cell | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |
IDOV_3731 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M-Luc | Concentration of cell lineNA | In-vitro toxicityNA | AssayAbsorbance measurements | In-vitro virus concentration10 MOI | In-vitro result18% cell viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryVirus induce apoptosis in cancer cell | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |
IDOV_3753 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.0001 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3754 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3755 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result98% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3756 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3757 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result100% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3758 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro result100% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3767 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3768 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result50% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3769 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (5 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3770 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (5 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result30% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_4126 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with drug Gemcitabine (0.01 ng/ml) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 vp/cell | In-vitro result80% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4127 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with drug Gemcitabine (1 ng/ml) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1000 vp/cell | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4128 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with drug Gemcitabine (10 ng/ml) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10000 vp/cell | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4129 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with drug Gemcitabine (100 ng/ml) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100000 vp/cell | In-vitro result100% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4130 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with drug Gemcitabine (1000 ng/ml) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1000000 vp/cell | In-vitro result100% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4131 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 vp/cell | In-vitro result100% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4132 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1000 vp/cell | In-vitro result85% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4133 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10000 vp/cell | In-vitro result35% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4134 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100000 vp/cell | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4135 | Virus nameAdenovirus | Virus strainAduPARE1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of E1A gene upstream of uPAR promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1000000 vp/cell | In-vitro result100% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26227809 |
IDOV_4308 | Virus nameAlphavirus | Virus strainM1 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate adenocarcinoma | Cell linePC-3 | Concentration of cell line4000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 pfu | In-vitro result72.7 % cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis | Immunogenic effectNA | Clinical trialNA | PMID26373347 |
IDOV_4330 | Virus nameAlphavirus | Virus strainM1 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreas adenocarcinoma | Cell lineBxPC-3 | Concentration of cell line4000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 pfu | In-vitro result98.8 % cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis | Immunogenic effectNA | Clinical trialNA | PMID26373347 |
IDOV_4909 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4910 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4911 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4912 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration50 MOI | In-vitro result100% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4913 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of IL21 gene in virus genome | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-21 gene | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4914 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of IL21 gene in virus genome | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-21 gene | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result90% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4915 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of IL21 gene in virus genome | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-21 gene | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result30% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4916 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of IL21 gene in virus genome | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-21 gene | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration50 MOI | In-vitro result15% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4917 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of IL21 and CCL21gene in virus genome | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-21 and CCL21 gene | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4918 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of IL21 and CCL21gene in virus genome | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-21 and CCL21 gene | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result40% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4919 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of IL21 and CCL21gene in virus genome | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-21 and CCL21 gene | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result15% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_4920 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of IL21 and CCL21gene in virus genome | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-21 and CCL21 gene | Source of cell lineJilin University china | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3M | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration50 MOI | In-vitro result15% cell viability after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivate proloferation of B-cell and Naive T-cell | Clinical trialNA | PMID27157859 |
IDOV_5065 | Virus nameAvian orthoreovirus | Virus strainARV-PB1 | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePC-3 | Concentration of cell line1.0E+3 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro result80% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28441762 |
IDOV_5072 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5073 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result98% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5074 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration4 MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5075 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5076 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 MOI | In-vitro result55% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5077 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationVirus in combination with SNS032 5ng/ml | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result55% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5078 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationVirus in combination with SNS032 10ng/ml | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result45% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5079 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationVirus in combination with SNS032 20ng/ml | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration4 MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5080 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationVirus in combination with SNS032 40ng/ml | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5081 | Virus nameAdenovirus | Virus strainZD-55-TRAIl-IETD-smac | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of TRAIL and smac gene via IETD linker | Virus aloneYes | Virus in combination with drug/radiationVirus in combination with SNS032 80ng/ml | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28440486 |
IDOV_5559 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayNA | In-vitro virus concentration1 MOI | In-vitro resultSignificant death of cancer cell line after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectNA | Clinical trialNA | PMIDUS7270812B2 |
IDOV_5564 | Virus nameReovirus | Virus strainwild type | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayNA | In-vitro virus concentration1 MOI | In-vitro resultSignificant death of cancer cell line after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectNA | Clinical trialNA | PMIDUS7270812B2 |
IDOV_5569 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationSindbis virus in combination with Reovirus | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cell line | Cell lineBxPC-3 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayNA | In-vitro virus concentration1 MOI | In-vitro resultEnhancer cytolytic effect in combination after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectNA | Clinical trialNA | PMIDUS7270812B2 |
IDOV_5575 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismNude mice xenografted subcutaneously for BxPC3 | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to below 2.0 cm after 10 weeks | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectNA | Clinical trialNA | PMIDUS7270812B2 |
IDOV_5576 | Virus nameReovirus | Virus strainwild type | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismNude mice xenografted subcutaneously for BxPC3 | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to below 3.0 cm after 10 weeks | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectNA | Clinical trialNA | PMIDUS7270812B2 |
IDOV_5577 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationSindbis virus in combination with Reovirus | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismNude mice xenografted subcutaneously for BxPC3 | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultComplete reduction in tumor volume after 10 weeks | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectNA | Clinical trialNA | PMIDUS7270812B2 |
IDOV_5578 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismNude mice xenografted subcutaneously for MIAPaCa-2 | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to below 5.0 cm after 12 weeks | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectNA | Clinical trialNA | PMIDUS7270812B2 |
IDOV_5579 | Virus nameReovirus | Virus strainwild type | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman pancreatic cell line | Cell lineBxPC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismNude mice xenografted subcutaneously for MIAPaCa-2 | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to below 4.0 cm after 12 weeks | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectNA | Clinical trialNA | PMIDUS7270812B2 |
IDOV_5623 | Virus nameNewcastle disease virus | Virus strainNDV-MK107 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell line80% confluency | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3×10³ pfu | In-vitro result50% of cancer cell death occurs | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectInduction of IFN-Gamma production | Clinical trialNA | PMIDUS7470426 |
IDOV_5843 | Virus nameNewcastle disease virus | Virus strainNDV-PPMK107 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostae carcinoma cell line | Cell linePC-3 | Concentration of cell line80% confluency | In-vitro toxicityNA | AssayNA | In-vitro virus concentration3.1 ×10³ pfu | In-vitro result50% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS8105578 |
IDOV_5888 | Virus nameRespiratory synctial virus | Virus strainMutant | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result20% cell survived after treatment | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMIDUS9241998 |
IDOV_5893 | Virus nameAdenovirus | Virus strainCGTG-602 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus E1A promoter is replaced by human E2F1 promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3-MM2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 ×10ⴠpfu | In-vitro resultAll cell death occurs after 100 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9410129 |