| Primary information |
|---|
| OV_ID | OV_4917 |
| Virus Name | Adenovirus |
| Strain | wild type |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | Addition of IL21 and CCL21gene in virus genome |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | Virus expressing IL-21 and CCL21 gene |
| Source of cell line | Jilin University china |
| Origin of cell line | Human prostate cancer cell line |
| Cell line | PC-3M |
| Concentration of cell line | 1 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 0.1 MOI |
| In-vitro result | 70% cell viability after 7 days |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | Activate proloferation of B-cell and Naive T-cell |
| Clinical trial | NA |
| PMID | 27157859 |