Detailed description page of Selected OV_ID


OV_3769 details
Primary information
OV_IDOV_3769
Virus Name Vaccinia virus
Strainvv-smac
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeInsertion of smac and gpt gene in TK
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with gemcitabine (5 micromolar)
Immune gene induction in virus genomeNo
Source of cell lineType culture collection of china
Origin of cell lineHuman pancreatic cancer cell line
Cell lineBxPC-3
Concentration of cell line5
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.1 MOI
In-vitro result40% cell viability after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce apoptosis in cancer cell
Immunogenic effectNA
Clinical trialNA
PMID30365143