Detailed description page of Selected OV_ID


OV_5579 details
Primary information
OV_IDOV_5579
Virus Name Reovirus
Strainwild type
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman pancreatic cell line
Cell lineBxPC-3
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismNude mice xenografted subcutaneously for MIAPaCa-2
In-vivo virus concentration1 ×10⁶ pfu
In-vivo toxicityNA
In-vivo resultTumor volume reduced to below 4.0 cm after 12 weeks
Mode of deliveryIntratumoral
Pathway inductionInduction of apoptosis by virus infection
Immunogenic effectNA
Clinical trialNA
PMIDUS7270812B2