Potential Epitope vaccine candidates

This page is designed to conclude our subunit vaccine candidates based on their prediction. We used a prediction pipeline for predicting the epitopes. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. In this page we have summarized all the peptides that were able to induce diverse arms of immune response. Here, we haev also displayed the strains according to their category in which the particular peptides were present. Here, user can search their vaccine candidates according the filter decided by the them. We hope this vaccine candidates have the full potential to be proceed further for experiment validation.


Total number of predicted 9mer peptides are 62



Sequence (9mer)Non tuberculoid MycobacteriaTuberculoid strainVaccine StrainsB cell Epitope scoreB cell confidence MHC class II alleles MHC class II alleles (count) MHC class I alleles MHC class I alleles (count) HLA Alleles HLA alleles count IFN-gamma inducing ScoreInducing IL4 cytokineIL4 inducing score
Sequence (9mer)Non tuberculoid MycobacteriaTuberculoid strainVaccine StrainsB cell Epitope scoreB cell confidence MHC class II alleles MHC class II alleles (count) MHC class I alleles MHC class I alleles (count) HLA Alleles HLA alleles count IFN-gamma inducing ScoreInducing IL4 cytokineIL4 inducing score
FAADVRANRM_kansasii_ATCC_12478, Mtb_H37RaM_africanum_GM041182, M_canettii_CIPT_140010059_3861, M_canettii_CIPT_140010059, M_canettii_CIPT_140060008, M_canettii_CIPT_140070008, M_canettii_CIPT_140070010, M_canettii_CIPT_140070017, Mtb_7199-99, Mtb_CCDC5079, Mtb_CCDC5180, Mtb_CDC_1551, Mtb_F11, Mtb_H37Rv_broad, Mtb_H37Rv, Mtb_KZN_1435, Mtb_KZN_4207-3996, Mtb_KZN_4207, Mtb_KZN_605, Mtb_KZN_R506, Mtb_KZN_V2475, Mtb_RGTB327, Mtb_RGTB423, Mtb_UT2050.4464.53DRB1_0305, DRB1_0309 2 HLA-A20 Cattle,HLA-A*3302,HLA-A68.1,HLA-B*51,HLA-B*5401 5 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 9 0.12 YES 0.45
FARAVRNAFMtb_CCDC5079, Mtb_CCDC51800.3461.23DRB1_0309, DRB1_1120, DRB1_1302 3 HLA-B*0702,HLA-B*3501,HLA-B*4403,HLA-B*51,HLA-B*5301,HLA-B*5401,HLA-B*5801,HLA-B62 8 HLA-A*0203,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 10 0.23 YES 0.40
FEDRTVAMLM_canettii_CIPT_140010059, M_canettii_CIPT_140070010, M_canettii_CIPT_1400700170.3762.32DRB1_0801, DRB1_0802 2 HLA-A*0205,HLA-A2.1,HLA-B*2705,HLA-B*3701,HLA-B40,HLA-B*4403,HLA-B*51,HLA-B*5301,HLA-B*5401,HLA-B60,HLA-B61,MHC-Kk 12 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 9 0.25 YES 0.28
FEGLMRRHIM_liflandiii_128FXT, M_marinum, Mtb_H37Ra, M_ulcerans_Agy99, M_vanbaalenii_PYR-1M_africanum_GM041182, M_canettii_CIPT_140010059_3861, M_canettii_CIPT_140010059, M_canettii_CIPT_140060008, M_canettii_CIPT_140070008, M_canettii_CIPT_140070010, M_canettii_CIPT_140070017, Mtb_7199-99, Mtb_CCDC5079, Mtb_CCDC5180, Mtb_CDC_1551, Mtb_CTRI-2, Mtb_F11, Mtb_H37Rv_broad, Mtb_H37Rv, Mtb_KZN_1435, Mtb_KZN_4207-3996, Mtb_KZN_4207, Mtb_KZN_605, Mtb_KZN_R506, Mtb_KZN_V2475, Mtb_RGTB327, Mtb_RGTB423, Mtb_UT205M_bovis_AF2122_97, M_bovis_BCG_str_Korea, M_bovis_BCG_str_Mexico, M_bovis_BCG_str_Pasteur_1173P2, M_bovis_BCG_str_Tokyo_1720.3461.22DRB1_0101, DRB1_0802, DRB1_1101, DRB1_1114, DRB1_1120, DRB1_1128, DRB1_1302, DRB1_1305, DRB1_1307, DRB1_1323 10 HLA-B*3701,HLA-B40,HLA-B*4403,HLA-B*51,HLA-B*5301,HLA-B*5401,HLA-B60,HLA-B61,MHC-Kk 9 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 9 0.05 YES 0.40
FERAVRNAFMtb_H37RaM_canettii_CIPT_140010059_3861, M_canettii_CIPT_140010059, M_canettii_CIPT_140060008, M_canettii_CIPT_140070008, M_canettii_CIPT_140070010, M_canettii_CIPT_140070017, Mtb_7199-99, Mtb_CDC_1551, Mtb_CTRI-2, Mtb_F11, Mtb_H37Rv_broad, Mtb_H37Rv, Mtb_KZN_1435, Mtb_KZN_4207-3996, Mtb_KZN_4207, Mtb_KZN_605, Mtb_KZN_R506, Mtb_KZN_V2475, Mtb_RGTB327, Mtb_UT205M_bovis_AF2122_97, M_bovis_BCG_str_Korea, M_bovis_BCG_str_Mexico, M_bovis_BCG_str_Pasteur_1173P2, M_bovis_BCG_str_Tokyo_1720.5467.86DRB1_0309, DRB1_1120, DRB1_1302 3 HLA-B*0702,HLA-B*2702,HLA-B*3701,HLA-B40,HLA-B*4403,HLA-B*51,HLA-B*5301,HLA-B*5401,MHC-Kk 9 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 9 0.54 YES 0.35
FLGGGVILRM_avium_104, M_avium_K-10, M_indicus_prani_MTCC_9506, M_intracellulare_ATCC_13950, M_intracellulare_MOTT-02, M_intracellulare_MOTT-64, M_kansasii_ATCC_12478, M_liflandiii_128FXT, M_marinum, Mtb_H37Ra, M_ulcerans_Agy99, Mycobacterium_sp_JDM601, Mycobacterium_sp_MOTT36YM_africanum_GM041182, M_canettii_CIPT_140010059_3861, M_canettii_CIPT_140010059, M_canettii_CIPT_140060008, M_canettii_CIPT_140070008, M_canettii_CIPT_140070010, M_canettii_CIPT_140070017, Mtb_7199-99, Mtb_CCDC5079, Mtb_CCDC5180, Mtb_CDC_1551, Mtb_CTRI-2, Mtb_F11, Mtb_H37Rv_broad, Mtb_H37Rv, Mtb_KZN_1435, Mtb_KZN_4207-3996, Mtb_KZN_4207, Mtb_KZN_605, Mtb_KZN_R506, Mtb_KZN_V2475, Mtb_RGTB327, Mtb_RGTB423, Mtb_UT205M_bovis_AF2122_97, M_bovis_BCG_str_Korea, M_bovis_BCG_str_Mexico, M_bovis_BCG_str_Pasteur_1173P2, M_bovis_BCG_str_Tokyo_1720.5467.97DRB1_0305, DRB1_0309 2 HLA-A*1101,HLA-A20 Cattle,HLA-A3,HLA-A*3101,HLA-A*3302,HLA-A68.1,HLA-B*51,HLA-B*5401 8 HLA-A*0301,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 10 0.99 YES 0.26
FQRVGLRRRMtb_H37RaM_africanum_GM041182, M_canettii_CIPT_140010059_3861, M_canettii_CIPT_140010059, M_canettii_CIPT_140060008, M_canettii_CIPT_140070008, M_canettii_CIPT_140070010, M_canettii_CIPT_140070017, Mtb_7199-99, Mtb_CCDC5079, Mtb_CCDC5180, Mtb_CDC_1551, Mtb_CTRI-2, Mtb_F11, Mtb_H37Rv_broad, Mtb_H37Rv, Mtb_KZN_1435, Mtb_KZN_4207-3996, Mtb_KZN_4207, Mtb_KZN_605, Mtb_KZN_R506, Mtb_KZN_V2475, Mtb_RGTB327, Mtb_RGTB423, Mtb_UT205M_bovis_AF2122_97, M_bovis_BCG_str_Korea, M_bovis_BCG_str_Mexico, M_bovis_BCG_str_Pasteur_1173P2, M_bovis_BCG_str_Tokyo_1720.5167.03DRB1_1101, DRB1_1114, DRB1_1120, DRB1_1128, DRB1_1302, DRB1_1305, DRB1_1307, DRB1_1323, DRB5_0101, DRB5_0105 10 HLA-A20 Cattle,HLA-A*3101,HLA-A*3302,HLA-A68.1,HLA-B*2705,HLA-B*51,HLA-B*5401,HLA-B62 8 HLA-B14,HLA-B27,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01,HLA-B*2703,HLA-B*2704 13 0.50 YES 0.30
FRHDRQNRLM_canettii_CIPT_140010059, M_canettii_CIPT_140070010, M_canettii_CIPT_1400700170.5568.44DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0401, DRB1_0421, DRB1_0426, DRB1_0701, DRB1_0703, DRB1_1107 13 HLA-B*0702,HLA-B14,HLA-B*2702,HLA-B*2705,HLA-B*3901,HLA-B*3902,HLA-B*51,HLA-B*5301,HLA-B*5401,HLA-B8,MHC-Dd 11 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,HLA-B35,Mamu-A*01 10 0.02 YES 0.22
FRPLTLRRRMtb_H37RaM_africanum_GM041182, M_canettii_CIPT_140010059_3861, M_canettii_CIPT_140010059, M_canettii_CIPT_140060008, M_canettii_CIPT_140070008, M_canettii_CIPT_140070010, M_canettii_CIPT_140070017, Mtb_7199-99, Mtb_CCDC5079, Mtb_CCDC5180, Mtb_CDC_1551, Mtb_CTRI-2, Mtb_F11, Mtb_H37Rv_broad, Mtb_H37Rv, Mtb_KZN_1435, Mtb_KZN_4207-3996, Mtb_KZN_4207, Mtb_KZN_605, Mtb_KZN_R506, Mtb_KZN_V2475, Mtb_RGTB327, Mtb_RGTB423, Mtb_UT205M_bovis_AF2122_97, M_bovis_BCG_str_Korea, M_bovis_BCG_str_Mexico, M_bovis_BCG_str_Pasteur_1173P2, M_bovis_BCG_str_Tokyo_1720.5267.19DRB1_0101, DRB1_0801, DRB1_0802, DRB1_1101, DRB1_1102, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1305, DRB1_1307, DRB1_1321, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328, DRB5_0101, DRB5_0105 20 HLA-A20 Cattle,HLA-B*2702,HLA-B*2705,HLA-B*51,HLA-B*5401 5 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 9 0.64 NO -0.01
FVNWEGRYRM_kansasii_ATCC_12478, M_liflandiii_128FXT, M_marinum, Mtb_H37Ra, M_ulcerans_Agy99M_africanum_GM041182, M_canettii_CIPT_140010059_3861, M_canettii_CIPT_140010059, M_canettii_CIPT_140070008, M_canettii_CIPT_140070010, M_canettii_CIPT_140070017, Mtb_7199-99, Mtb_CCDC5079, Mtb_CCDC5180, Mtb_CDC_1551, Mtb_CTRI-2, Mtb_F11, Mtb_H37Rv_broad, Mtb_H37Rv, Mtb_KZN_1435, Mtb_KZN_4207-3996, Mtb_KZN_4207, Mtb_KZN_605, Mtb_KZN_R506, Mtb_KZN_V2475, Mtb_UT205M_bovis_AF2122_97, M_bovis_BCG_str_Korea, M_bovis_BCG_str_Mexico, M_bovis_BCG_str_Pasteur_1173P2, M_bovis_BCG_str_Tokyo_1720.3661.95DRB1_0402, DRB1_1102, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328, DRB5_0101, DRB5_0105 13 HLA-A20 Cattle,HLA-A*3302,HLA-A68.1,HLA-B*51,HLA-B*5401 5 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 9 0.28 YES 0.28
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