Strain Card

The is the strain card and all its information available in our database. Thhe information includes the result of experiemtnal epitope mapping and prediction from various algorithms. Experimental epitopes were mapped from IEDB repository were B cell, T cell and MHC binders. The prediction tools including B cell epitope (LBtope), MHC class I binding alleles (Propred1), MHC class II binding alleles (Propred), CTL epitope (CTLpred), HLA alleles (nHLApred), interferon-gamma inducing potential (IFNepitope), Interleukin-4 inducing capacity (IL4pred).
DescriptionThis strain has been derived from the original human-lung H37 isolate in 1934, and has been used extensively worldwide in biomedical research. Unlike some clinical isolates, it retains full virulence in animal models of tuberculosis and is susceptible to drugs and receptive to genetic manipulation.
CategoryVirulent lab strain
Genome visualizationUsing Jbrowse, CGview, Argo applet
Number of proteins4003
B cell epitopes (IEDB)96
T cell epitopes (IEDB)234
MHC binder (IEDB)361
No. of Vaccine Target166
B cell prediction (LBtope)5286
Prediction of MHC class II binders (Propred)9717
MHC class I prediction (Propred1)45439
CTL epitope prediction (CTLpred)10684
Prediction of Interferon-gamma inducing peptides (IFNepitope)27574
Prediction of IL4 inducing peptides (IL4pred)42799