Potential Vaccine Candidates

This page is to designed to select vaccine candidates for recombinant BCG or subunit vaccine. Here, we have provded the detailed table for 178 vaccine candidates. For each potential candidates, information was provided that in which strain according to their category (tuberculoid, NTM, vaccine) it is present and how many MHC binders, B cell and T cell epitopes (experimentally known) were mapped. These proteins were searched using needleall program of EMBOSS for global alignment with the sequence identity cut off 95%.


S.N.Antigen TypeGene IDNon tuberculoid mycobacteriaTuberculoid StrainVaccine StrainB cell epitopeBcell epitope CountT cell epitopesT cell epitope countMHC bindersMHC binders count
1Virulent15607268 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070010 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CCDC5079 , Mtb_CCDC5180 , Mtb_CDC_1551 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB327 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 000
2Virulent15607295 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070010 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CCDC5180 , Mtb_CDC_1551 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB327 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 000
3Virulent15607307 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070010 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CCDC5079 , Mtb_CCDC5180 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 000
4Virulent15607323 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070010 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CDC_1551 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB423 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 000
5Virulent15607339 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CCDC5180 , Mtb_CDC_1551 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB423 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 0 TQVRDLIIQASQAGAA, 1 LAIDRDDLY, 1
6Virulent15607340 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070010 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CCDC5079 , Mtb_CCDC5180 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB327 , Mtb_RGTB423 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 000
7Virulent15607352 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070010 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CCDC5079 , Mtb_CCDC5180 , Mtb_CDC_1551 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB327 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 00 KVFFVNWFR, 1
8Virulent15607392 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070010 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CCDC5079 , Mtb_CCDC5180 , Mtb_CDC_1551 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB423 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 RGEHRDEHTQDAGDK, 100
9Virulent15607489 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140060008 , Mtb_7199-99 , Mtb_CCDC5079 , Mtb_CCDC5180 , Mtb_CDC_1551 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB327 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 000
10Virulent15607494 M_africanum_GM041182 , M_canettii_CIPT_140010059_3861 , M_canettii_CIPT_140010059 , M_canettii_CIPT_140060008 , M_canettii_CIPT_140070008 , M_canettii_CIPT_140070010 , M_canettii_CIPT_140070017 , Mtb_7199-99 , Mtb_CCDC5079 , Mtb_CCDC5180 , Mtb_CDC_1551 , Mtb_CTRI-2 , Mtb_F11 , Mtb_H37Rv_broad , Mtb_H37Rv , Mtb_KZN_1435 , Mtb_KZN_4207-3996 , Mtb_KZN_4207 , Mtb_KZN_605 , Mtb_KZN_R506 , Mtb_KZN_V2475 , Mtb_RGTB327 , Mtb_RGTB423 , Mtb_UT205 M_bovis_AF2122_97 , M_bovis_BCG_str_Korea , M_bovis_BCG_str_Mexico , M_bovis_BCG_str_Pasteur_1173P2 , M_bovis_BCG_str_Tokyo_172 000
Showing 1 to 10 of 178 entries