A database of hormones and their receptors

Non-peptide Hormone

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HMRbase accession number	1033
PubChem ID	222786
Hormone name	Cortisone
Description	A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Synonyms	Adrenalex Cortisate Cortistal Cortivite Andreson Cortisal Cortogen Cortone Adreson Cortisone
Molecular weight	360.44
Molecular formula	C₂₁H₂₈O₅
IUPAC Name	(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
Canonical smiles	CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4(C(=O)CO)O)C
Isomeric smiles	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C
Structure
PDB file
SDF file
MOL file
PDB ID	3EB3
KEGG ID	C00762 D07749
HMDB ID	HMDB02802
Melting Point	222(EXP)
Log P	1.47(EXP)
Water Solubility	280(EXP) at 25C
DrugBank ID	N/A
Drugpedia	wiki
Receptor	P79686 Detail in HMRbase Q6XLJ0 Detail in HMRbase P49115 Detail in HMRbase P04150 Detail in HMRbase P06537 Detail in HMRbase P49843 Detail in HMRbase O73673 Detail in HMRbase Q9N1U3 Detail in HMRbase Q5R9P5 Detail in HMRbase P59667 Detail in HMRbase P06536 Detail in HMRbase P79269 Detail in HMRbase O13186 Detail in HMRbase O46567 Detail in HMRbase P35547 Detail in HMRbase Q95267 Detail in HMRbase P49844 Detail in HMRbase Q3MSN1 Detail in HMRbase Q3MSN4 Detail in HMRbase O57353 Detail in HMRbase Q28023 Detail in HMRbase Q28551 Detail in HMRbase Q28890 Detail in HMRbase Q28981 Detail in HMRbase Q6EDZ0 Detail in HMRbase Q6IVJ3 Detail in HMRbase Q6QB13 Detail in HMRbase Q6RKQ3 Detail in HMRbase Q6TN19 Detail in HMRbase Q7TSX7 Detail in HMRbase Q865Y6 Detail in HMRbase Q8JHA4 Detail in HMRbase Q8JHA5 Detail in HMRbase Q8JJ90 Detail in HMRbase Q8JJ91 Detail in HMRbase Q8JJ92 Detail in HMRbase Q98SJ1 Detail in HMRbase
Comments	!Link to Receptor is not Organism Specific
References	Pubchem,HMDB