Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_1361 | Hyaluronic acid Click for more detail | NA | CC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | the activation of TLR4 by hyaluronic acid leads to a different pattern of gene induction | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | cell surface | O00206.fasta | O00206 | 839 | Possible effect in case of stroke i.e it is Involved in preconditioning, Up-regulation of TLR4 mRNA correlates with the severity of ischemia, TLR4-deficient animals have better outcome following cerebral ischemia | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1361 | Hyaluronic acid Click for more detail | NA | CC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | the activation of TLR4 by hyaluronic acid leads to a different pattern of gene induction | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | cell surface | O00206.fasta | O00206 | 839 | Possible effect in case of stroke i.e it is Involved in preconditioning, Up-regulation of TLR4 mRNA correlates with the severity of ischemia, TLR4-deficient animals have better outcome following cerebral ischemia | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1362 | hyaluronic acid oligosaccharides Click for more detail | plasma membrane (others) | CC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | the activation of TLR4 by hyaluronic acid leads to a different pattern of gene induction | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) | Q9QUK6.fasta | Q9QUK6 | 835 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1362 | hyaluronic acid oligosaccharides Click for more detail | plasma membrane (others) | CC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | the activation of TLR4 by hyaluronic acid leads to a different pattern of gene induction | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) | Q9QUK6.fasta | Q9QUK6 | 835 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1363 | hyaluronic acid oligosaccharides Click for more detail | plasma membrane (others) | CC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | the activation of TLR4 by hyaluronic acid leads to a different pattern of gene induction | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) | O00206.fasta | O00206 | 839 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1363 | hyaluronic acid oligosaccharides Click for more detail | plasma membrane (others) | CC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | the activation of TLR4 by hyaluronic acid leads to a different pattern of gene induction | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) | O00206.fasta | O00206 | 839 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1518 | oxidized lipids Click for more detail | Gram-negative bacteria | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | (DCs)Dendritic cells | cell surface | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | NA | 24825061 | 2014 | Pubchem_assay |
| PRRID_1518 | oxidized lipids Click for more detail | Gram-negative bacteria | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | (DCs)Dendritic cells | cell surface | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | NA | 24825061 | 2014 | Pubchem_assay |
| PRRID_1561 | peroxiredoxins Click for more detail | NA | MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK | 199 | Damage-associated molecular patterns (DAMPs) | Natural | released in brain injury | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | ischemic brain tissue | cell surface | Q9QUK6.fasta | Q9QUK6 | 835 | TLR4 signaling has been implicated in post-stroke neuroinflammation and injury and is also critical in the robustly neuroprotective ischemic preconditioning phenomenon | NA | 24784586 | 2014 | Pubchem_assay |
| PRRID_1561 | peroxiredoxins Click for more detail | NA | MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK | 199 | Damage-associated molecular patterns (DAMPs) | Natural | released in brain injury | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | ischemic brain tissue | cell surface | Q9QUK6.fasta | Q9QUK6 | 835 | TLR4 signaling has been implicated in post-stroke neuroinflammation and injury and is also critical in the robustly neuroprotective ischemic preconditioning phenomenon | NA | 24784586 | 2014 | Pubchem_assay |
| PRRID_1562 | peroxiredoxins Click for more detail | NA | MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK | 199 | Damage-associated molecular patterns (DAMPs) | Natural | released in brain injury | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | ischemic brain tissue | cell surface | O00206.fasta | O00206 | 839 | TLR4 signaling has been implicated in post-stroke neuroinflammation and injury and is also critical in the robustly neuroprotective ischemic preconditioning phenomenon | NA | 24784586 | 2014 | Pubchem_assay |
| PRRID_1562 | peroxiredoxins Click for more detail | NA | MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK | 199 | Damage-associated molecular patterns (DAMPs) | Natural | released in brain injury | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | ischemic brain tissue | cell surface | O00206.fasta | O00206 | 839 | TLR4 signaling has been implicated in post-stroke neuroinflammation and injury and is also critical in the robustly neuroprotective ischemic preconditioning phenomenon | NA | 24784586 | 2014 | Pubchem_assay |
| PRRID_1609 | S100 proteins Click for more detail | NA | MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE | 92 | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | (DCs)Dendritic cells | cell surface | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | NA | 24825061 | 2014 | Pubchem_assay |
| PRRID_1609 | S100 proteins Click for more detail | NA | MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE | 92 | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | (DCs)Dendritic cells | cell surface | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | NA | 24825061 | 2014 | Pubchem_assay |
| PRRID_1671 | Uric acid Click for more detail | Host (Endogenous) (others) | C12=C(NC(=O)N1)NC(=O)NC2=O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Keratinocytes and mouse skin | cell surface | Q9QUK6.fasta | Q9QUK6 | 835 | play a role in UVB induced immune suppression | NA | 24786223 | 2014 | Pubchem_assay |
| PRRID_1671 | Uric acid Click for more detail | Host (Endogenous) (others) | C12=C(NC(=O)N1)NC(=O)NC2=O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Keratinocytes and mouse skin | cell surface | Q9QUK6.fasta | Q9QUK6 | 835 | play a role in UVB induced immune suppression | NA | 24786223 | 2014 | Pubchem_assay |
| PRRID_1672 | Uric acid Click for more detail | Host (Endogenous) (others) | C12=C(NC(=O)N1)NC(=O)NC2=O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Keratinocytes and mouse skin | cell surface | O00206.fasta | O00206 | 839 | play a role in UVB induced immune suppression | NA | 24786223 | 2014 | Pubchem_assay |
| PRRID_1672 | Uric acid Click for more detail | Host (Endogenous) (others) | C12=C(NC(=O)N1)NC(=O)NC2=O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Keratinocytes and mouse skin | cell surface | O00206.fasta | O00206 | 839 | play a role in UVB induced immune suppression | NA | 24786223 | 2014 | Pubchem_assay |
| PRRID_1715 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | Activate NF-Kb | NA | 27293318 | 2016 | NA |
| PRRID_1715 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | Activate NF-Kb | NA | 27293318 | 2016 | NA |
| PRRID_1899 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | NA | NA | Q96P20.fasta | Q96P20 | 1036 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1899 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | NA | NA | Q96P20.fasta | Q96P20 | 1036 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1900 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | NA | NA | Q9C000.fasta | Q9C000 | 1473 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1900 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | NA | NA | Q9C000.fasta | Q9C000 | 1473 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1901 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | NA | NA | P16671.fasta | P16671 | 472 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1901 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | NA | NA | P16671.fasta | P16671 | 472 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1902 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | cluster of differentiation 14 (CD14) | Pattern recognition receptor (PRR) | Human | NA | NA | P08571.fasta | P08571 | 375 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1902 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | cluster of differentiation 14 (CD14) | Pattern recognition receptor (PRR) | Human | NA | NA | P08571.fasta | P08571 | 375 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1903 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1903 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1904 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | RAGE | Receptor for advanced glycation endproducts (RAGE) | Human | NA | NA | Q15109.fasta | Q15109 | 404 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1904 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | RAGE | Receptor for advanced glycation endproducts (RAGE) | Human | NA | NA | Q15109.fasta | Q15109 | 404 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1905 | Actin Click for more detail | Cytosol(others) | MDGEDVQALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGGVSHTVPIYEGYALPHAILRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLAYVALDFEAEMQTAASSSALEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYGNVVLSGGTTMFPGIADRMNKELTALAPSKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKEEYDESGPSIVHRKCF | 376 | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Dendritic cell NK lectin group receptor | NA | NA | NA | NA | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1905 | Actin Click for more detail | Cytosol(others) | MDGEDVQALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGGVSHTVPIYEGYALPHAILRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLAYVALDFEAEMQTAASSSALEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYGNVVLSGGTTMFPGIADRMNKELTALAPSKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKEEYDESGPSIVHRKCF | 376 | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Dendritic cell NK lectin group receptor | NA | NA | NA | NA | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1909 | Aggrecan Click for more detail | Proteoglycan (others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1909 | Aggrecan Click for more detail | Proteoglycan (others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1911 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Microglia | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NLRP3 inflammasome activation in AD models | NA | 28805121 | 2017 | Pubchem_assay |
| PRRID_1911 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Microglia | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NLRP3 inflammasome activation in AD models | NA | 28805121 | 2017 | Pubchem_assay |
| PRRID_1912 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ↑ in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1912 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ↑ in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1913 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Brain | NA | Q96P20.fasta | Q96P20 | 1036 | protein ↑ in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1913 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Brain | NA | Q96P20.fasta | Q96P20 | 1036 | protein ↑ in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1914 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1914 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1915 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | substantia nigra | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1915 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | substantia nigra | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1925 | ATP Click for more detail | Mitochondria (others) | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | P2X7 | Pattern recognition receptor (PRR) | NA | NA | NA | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1925 | ATP Click for more detail | Mitochondria (others) | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | P2X7 | Pattern recognition receptor (PRR) | NA | NA | NA | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1926 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Microglia | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NLRP3 inflammasome activation in AD models | NA | 28805121 | 2017 | Pubchem_assay |
| PRRID_1926 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Microglia | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NLRP3 inflammasome activation in AD models | NA | 28805121 | 2017 | Pubchem_assay |
| PRRID_1927 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1927 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1928 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Brain | NA | Q96P20.fasta | Q96P20 | 1036 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1928 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Brain | NA | Q96P20.fasta | Q96P20 | 1036 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1929 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1929 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1930 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | substantia nigra | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1930 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | substantia nigra | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1931 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Activate human dendritic cells | P2X7R | NOD-like receptor (NLR) | Human | Dendritic cells | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1931 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Activate human dendritic cells | P2X7R | NOD-like receptor (NLR) | Human | Dendritic cells | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1932 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Activate human dendritic cells | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Dendritic cells | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1932 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Activate human dendritic cells | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Dendritic cells | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1933 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β and IL-18 by human monocytes | P2X7R | NOD-like receptor (NLR) | Human | Monocyte | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1933 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β and IL-18 by human monocytes | P2X7R | NOD-like receptor (NLR) | Human | Monocyte | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1934 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β and IL-18 by human monocytes | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Monocyte | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1934 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β and IL-18 by human monocytes | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Monocyte | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1935 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β by murine and human neutrophils | P2X7R | NOD-like receptor (NLR) | Human | Neutrophils | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1935 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β by murine and human neutrophils | P2X7R | NOD-like receptor (NLR) | Human | Neutrophils | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1936 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β by murine and human neutrophils | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Neutrophils | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1936 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β by murine and human neutrophils | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Neutrophils | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1980 | Chromogranin A Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | activate microglial cells | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | Activate NF-KB | NA | 28049142 | 2017 | NA |
| PRRID_1980 | Chromogranin A Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | activate microglial cells | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | Activate NF-KB | NA | 28049142 | 2017 | NA |
| PRRID_1981 | Chromogranin A Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | activate microglial cells | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | NA | NA | Q96P20.fasta | Q96P20 | 1036 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1981 | Chromogranin A Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | activate microglial cells | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | NA | NA | Q96P20.fasta | Q96P20 | 1036 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1982 | Chromogranin A Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | activate microglial cells | RAGE | Receptor for advanced glycation endproducts (RAGE) | Human | NA | NA | Q15109.fasta | Q15109 | 404 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1982 | Chromogranin A Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | activate microglial cells | RAGE | Receptor for advanced glycation endproducts (RAGE) | Human | NA | NA | Q15109.fasta | Q15109 | 404 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1995 | Decorin Click for more detail | Proteoglycan (others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1995 | Decorin Click for more detail | Proteoglycan (others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1996 | Decorin Click for more detail | Proteoglycan (others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1996 | Decorin Click for more detail | Proteoglycan (others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2016 | endogenous glycoproteins Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Mannose Receptor 1 | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2016 | endogenous glycoproteins Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Mannose Receptor 1 | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2017 | endogenous glycoproteins Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Dectin-1 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2017 | endogenous glycoproteins Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | Dectin-1 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2026 | Fibrinogen Click for more detail | ECM glycoprotein(others) | MQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSIRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG | 211 | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2026 | Fibrinogen Click for more detail | ECM glycoprotein(others) | MQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSIRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG | 211 | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2027 | Fibrinogen Click for more detail | Host (Endogenous) (others) | MQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSIRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG | 211 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Mouse podocytes | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2027 | Fibrinogen Click for more detail | Host (Endogenous) (others) | MQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSIRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG | 211 | Damage-associated molecular patterns (DAMPs) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Mouse podocytes | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2097 | Heat shock protein Click for more detail | Cytosol(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2097 | Heat shock protein Click for more detail | Cytosol(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2098 | Heat shock protein Click for more detail | Cytosol(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2098 | Heat shock protein Click for more detail | Cytosol(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2099 | Heat shock protein Click for more detail | Cytosol(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | cluster of differentiation 91 (CD91) | Pattern recognition receptor (PRR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2099 | Heat shock protein Click for more detail | Cytosol(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | cluster of differentiation 91 (CD91) | Pattern recognition receptor (PRR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_2102 | Heat shock protein Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | plays a cytoprotective role in Alzeihmer Disease by suppression of Ab aggregation enhancing the clearance of Ab, restoring homeostasis, and inhibiting neuronal apoptosis | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_2102 | Heat shock protein Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | plays a cytoprotective role in Alzeihmer Disease by suppression of Ab aggregation enhancing the clearance of Ab, restoring homeostasis, and inhibiting neuronal apoptosis | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_2103 | Heat shock protein Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | plays a cytoprotective role in Alzeihmer Disease by suppression of Ab aggregation enhancing the clearance of Ab, restoring homeostasis, and inhibiting neuronal apoptosis | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_2103 | Heat shock protein Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | plays a cytoprotective role in Alzeihmer Disease by suppression of Ab aggregation enhancing the clearance of Ab, restoring homeostasis, and inhibiting neuronal apoptosis | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_2104 | Heat shock protein Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | plays a cytoprotective role in Alzeihmer Disease by suppression of Ab aggregation enhancing the clearance of Ab, restoring homeostasis, and inhibiting neuronal apoptosis | cluster of differentiation 91 (CD91) | Pattern recognition receptor (PRR) | Human | NA | NA | Q71UW0.fasta | Q71UW0 | 92 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_2104 | Heat shock protein Click for more detail | NA | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | plays a cytoprotective role in Alzeihmer Disease by suppression of Ab aggregation enhancing the clearance of Ab, restoring homeostasis, and inhibiting neuronal apoptosis | cluster of differentiation 91 (CD91) | Pattern recognition receptor (PRR) | Human | NA | NA | Q71UW0.fasta | Q71UW0 | 92 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |