Primary information |
---|
PRRID | PRRID_1609 |
Ligand Name | S100 proteins |
Source | NA |
Sequence of ligand | MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE |
Length | 92 |
Type | Damage-associated molecular patterns (DAMPs) |
Occurence | Natural |
Role of Ligand | elicit innate immune response |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | (DCs)Dendritic cells |
Domain | cell surface |
Sequence of Receptor | Q9QUK6.fasta |
Swiss prot ID | Q9QUK6 |
Length Of Receptor | 835 |
Function | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system |
Assay used | NA |
PMID | 24825061 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1609 |
Ligand Name | S100 proteins |
Source | NA |
Sequence of ligand | MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE |
Length | 92 |
Type | Damage-associated molecular patterns (DAMPs) |
Occurence | Natural |
Role of Ligand | elicit innate immune response |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | (DCs)Dendritic cells |
Domain | cell surface |
Sequence of Receptor | Q9QUK6.fasta |
Swiss prot ID | Q9QUK6 |
Length Of Receptor | 835 |
Function | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system |
Assay used | NA |
PMID | 24825061 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |