| Primary information |
|---|
| PRRID | PRRID_1672 |
| Ligand Name | Uric acid |
| Source | Host (Endogenous) (others) |
| Sequence of ligand | C12=C(NC(=O)N1)NC(=O)NC2=O |
| Length | NA |
| Type | Damage-associated molecular patterns (DAMPs) |
| Occurence | Natural |
| Role of Ligand | Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Keratinocytes and mouse skin |
| Domain | cell surface |
| Sequence of Receptor | O00206.fasta |
| Swiss prot ID | O00206 |
| Length Of Receptor | 839 |
| Function | play a role in UVB induced immune suppression |
| Assay used | NA |
| PMID | 24786223 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1672 |
| Ligand Name | Uric acid |
| Source | Host (Endogenous) (others) |
| Sequence of ligand | C12=C(NC(=O)N1)NC(=O)NC2=O |
| Length | NA |
| Type | Damage-associated molecular patterns (DAMPs) |
| Occurence | Natural |
| Role of Ligand | Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Keratinocytes and mouse skin |
| Domain | cell surface |
| Sequence of Receptor | O00206.fasta |
| Swiss prot ID | O00206 |
| Length Of Receptor | 839 |
| Function | play a role in UVB induced immune suppression |
| Assay used | NA |
| PMID | 24786223 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |