Representation of Major Biochemical Pathway categories by the genes in PCMdb


A list of genes in PCMdb that can be classified as "Negative Regulators of Signaling" by UniProt database has been provided below.

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Gene Symbol Gene Name # of Entries
ADAM8adenosine deaminase1
ADAMTSL2ADAMTS-like 21
ADMadrenomedullin1
ADRA1Aadrenoceptor alpha 1A31
ADRA2Aadrenoceptor alpha 2A10
AKT1v-akt murine thymoma viral oncogene homolog 19
AMBPalpha-1-microglobulin/bikunin precursor20
ANKRD6ankyrin repeat domain 61
AP2A1adaptor-related protein complex 2, alpha 1 subunit9
AP2A2adaptor-related protein complex 2, alpha 2 subunit1
APCadenomatosis polyposis coli 2244
APCDD1Ladenomatous polyposis coli1
APOA1apolipoprotein A-I13
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 720
ATXN1ataxin 11
AVPR1Aarginine vasopressin receptor 1A10
BAMBIBMP and activin membrane-bound inhibitor homolog (Xenopus laevis)9
BARX1BARX homeobox 110
BCL2L2B-cell CLL/lymphoma 21
BCL6B-cell CLL/lymphoma 61
BMP4bone morphogenetic protein 414
BMP7bone morphogenetic protein 729
C19orf29cactin, spliceosome C complex subunit1
C1orf187dorsal inhibitory axon guidance protein1
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta21
CARD15nucleotide-binding oligomerization domain containing 213
CASP8caspase 8, apoptosis-related cysteine peptidase13
CAV2caveolin 21
CBLBCbl proto-oncogene, E3 ubiquitin protein ligase B1
CBLCCbl proto-oncogene, E3 ubiquitin protein ligase C40
CCL5chemokine (C-C motif) ligand 520
CCND1cyclin D114
CD44CD44 molecule (Indian blood group)5
CDH23cadherin 2, type 1, N-cadherin (neuronal)1
CHST10carbohydrate (chondroitin 4) sulfotransferase 1120
CIDEAcell death-inducing DFFA-like effector a50
CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 11
CMYA5cardiomyopathy associated 51
COX2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)11
CRHR2corticotropin releasing hormone receptor 241
CRIPAKcysteine-rich PAK1 inhibitor9
CYP26B1cytochrome P450, family 26, subfamily B, polypeptide 130
CYP26C1cytochrome P450, family 26, subfamily C, polypeptide 111
CYP7B1cytochrome P450, family 7, subfamily B, polypeptide 11
DAB1Dab, reelin signal transducer, homolog 1 (Drosophila)37
DACT3dishevelled-binding antagonist of beta-catenin 31
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked1
DGKZdiacylglycerol kinase, zeta20
DKK1dickkopf WNT signaling pathway inhibitor 16
DKK2dickkopf WNT signaling pathway inhibitor 246
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