Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 100. Click on ID to see further detail.
IDOV_5108 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5109 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5110 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5111 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5112 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5113 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5114 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5115 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5116 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineSK-MEL-2 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5117 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineSK-MEL-2 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result40% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5118 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineSK-MEL-2 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5119 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineSK-MEL-2 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result100% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5120 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineSK-MEL-2 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result90% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5121 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineSK-MEL-2 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result70% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5122 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineSK-MEL-2 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5123 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineSK-MEL-2 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result100% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5124 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismC57BL/6 mice xenograft for B16-OVA (1.0E+5 cells) | In-vivo virus concentration3.0E+6 on day 0 and 1.0E+6 on day 2 | In-vivo toxicityNA | In-vivo resultReduction in tumor volume to 100 cubic mm compared to control 500 cubic mm after 12 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5125 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismC57BL/6 mice xenograft for B16-OVA (1.0E+5 cells) | In-vivo virus concentration3.0E+6 on day 0 and 1.0E+6 on day 2 | In-vivo toxicityNA | In-vivo resultComplete reduction in tumor volumecompared to control 500 cubic mm after 12 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5413 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine lymphosarcoma cell line | Cell lineRLS | Concentration of cell line80% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result90% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5414 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine lymphosarcoma cell line | Cell lineRLS | Concentration of cell line80% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5415 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine lymphosarcoma cell line | Cell lineRLS | Concentration of cell line80% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result50% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5416 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine lymphosarcoma cell line | Cell lineRLS-40 | Concentration of cell line80% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result90% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5417 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine lymphosarcoma cell line | Cell lineRLS-40 | Concentration of cell line80% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result90% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5418 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine lymphosarcoma cell line | Cell lineRLS-40 | Concentration of cell line80% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5419 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine melanoma | Cell lineB16 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result57% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5420 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine melanoma | Cell lineB16 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result42% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5421 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineMurine melanoma | Cell lineB16 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result22% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5422 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineHuman cervical carcinoma | Cell lineKB-3-1 | Concentration of cell line9.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result64% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5423 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineHuman cervical carcinoma | Cell lineKB-3-1 | Concentration of cell line9.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result40% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5424 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineHuman cervical carcinoma | Cell lineKB-3-1 | Concentration of cell line9.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result17% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5425 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineHuman cervical carcinoma | Cell lineKB-8-5 | Concentration of cell line9.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5426 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineHuman cervical carcinoma | Cell lineKB-8-5 | Concentration of cell line9.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5427 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineRussian academy of science | Origin of cell lineHuman cervical carcinoma | Cell lineKB-8-5 | Concentration of cell line9.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result35% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5428 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismC57Bl6 mice subcutaneous injected for 1.0E+5 B16 cells | In-vivo virus concentration5.0E+7 pfu | In-vivo toxicityNA | In-vivo resultReduction in tumor volume to below 0.3 cubic cm compared to control 1.2 cubic cm after 20 days | Mode of deliveryIntratumoral | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5429 | Virus nameVaccinia virus | Virus strainLIVP-GFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion mutant for tk gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismCBA mice sintramuscularly injected for 5.0E+7 RLS-40 cells | In-vivo virus concentration5.0E+7 pfu | In-vivo toxicityNA | In-vivo resultReduction in tumor volume to below 0.2 cubic cm compared to control 0.8 cubic cm after 15 days | Mode of deliveryIntratumoral | Pathway inducedReduction production of IL-6 indicating tumor inhibition | Immunogenic effectNA | Clinical trialNA | PMID27538520 |
IDOV_5457 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c mice injected with tumor | In-vivo virus concentration1.0E+4 pfu | In-vivo toxicityNA | In-vivo resultMice failed to develop cancer | Mode of deliverySubcutaneous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS41098983 |
IDOV_5458 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c mice injected with tumor | In-vivo virus concentration1.0E+5 pfu | In-vivo toxicityNA | In-vivo resultMice failed to develop cancer | Mode of deliverySubcutaneous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS41098983 |
IDOV_5459 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c mice injected with tumor | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultMice failed to develop cancer | Mode of deliverySubcutaneous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS41098983 |
IDOV_5682 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 261.8mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5683 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 248.4mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5684 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 216.8mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5685 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 208.8mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5686 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 157.2mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5687 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 280.3mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5688 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 301.9mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5689 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 273.5mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5690 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 243.8mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5691 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 286mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5692 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 267.1mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5693 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 155.6mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5694 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 310.9mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5695 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 416.9mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5696 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 536.1mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5697 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 5550.4mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5698 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 463.4mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5699 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 543.3mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5700 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 320.1mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5701 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 679mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5702 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 660mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5703 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 701.4mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5704 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 761.3mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5705 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 706.6mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5706 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 721.3mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5707 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 476.3mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5708 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 864.1mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5709 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 828.6mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5710 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 978.4mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5711 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 852mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5712 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 985.5mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5713 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 936.1mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5714 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 695mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5715 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 1179.9mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5716 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 897.4mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5717 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 1485mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5718 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 1053mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5719 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 852mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5720 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 606mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5721 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 751mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5722 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 166.7mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5723 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultComplete regression in tumor volume after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5724 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 1536.9mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5725 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 962.2mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5726 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 579.2mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5727 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 546.9mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5728 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 720.1mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5729 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 117.8mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5730 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultComplete regression in tumor volume after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5731 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 412.9mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5732 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 350.2mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5733 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 341.1mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5734 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 353.4mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5735 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 392.25mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5736 | Virus nameVaccinia virus | Virus strainGLV-1h84 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 305.6mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5737 | Virus nameVaccinia virus | Virus strainGLV-1h85 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 350.65mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5738 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 419.55mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5739 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 750.4mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5740 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 722.3mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5741 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 819.8mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5742 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1081.2mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5743 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1222.25mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |