Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5108Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTS assay0.001 MOI100% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5109Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTS assay0.01 MOI80% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5110Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTS assay0.1 MOI50% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5111Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTS assay1 MOI10% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5112Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTS assay0.001 MOI100% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5113Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTS assay0.01 MOI100% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5114Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTS assay0.1 MOI60% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5115Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTS assay1 MOI10% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5116Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineSK-MEL-21.0E+4 cells per wellNAMTS assay0.001 MOI60% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5117Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineSK-MEL-21.0E+4 cells per wellNAMTS assay0.01 MOI40% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5118Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineSK-MEL-21.0E+4 cells per wellNAMTS assay0.1 MOI10% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5119Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineSK-MEL-21.0E+4 cells per wellNAMTS assay1 MOI100% cell killingNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5120Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineSK-MEL-21.0E+4 cells per wellNAMTS assay0.001 MOI90% cell killingNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5121Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineSK-MEL-21.0E+4 cells per wellNAMTS assay0.01 MOI70% cell killingNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5122Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineSK-MEL-21.0E+4 cells per wellNAMTS assay0.1 MOI20% cell killingNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5123Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineSK-MEL-21.0E+4 cells per wellNAMTS assay1 MOI100% cell killingNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5124Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneNANANANANANANANAC57BL/6 mice xenograft for B16-OVA (1.0E+5 cells)3.0E+6 on day 0 and 1.0E+6 on day 2NA Reduction in tumor volume to 100 cubic mm compared to control 500 cubic mm after 12 daysIntratumoralNAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5125Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneNANANANANANANANAC57BL/6 mice xenograft for B16-OVA (1.0E+5 cells)3.0E+6 on day 0 and 1.0E+6 on day 2NA Complete reduction in tumor volumecompared to control 500 cubic mm after 12 daysIntratumoralNAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5413Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS80% confluenceNAMTT assay1 MOI90% cell viability after 24 hoursNoNoNA No responseNANANANA27538520
OV_5414Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS80% confluenceNAMTT assay1 MOI80% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5415Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS80% confluenceNAMTT assay1 MOI50% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5416Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS-4080% confluenceNAMTT assay1 MOI90% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5417Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS-4080% confluenceNAMTT assay1 MOI90% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5418Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS-4080% confluenceNAMTT assay1 MOI80% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5419Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine melanomaB163.0E+3 cells per wellNAMTT assay1 MOI57% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5420Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine melanomaB163.0E+3 cells per wellNAMTT assay1 MOI42% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5421Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine melanomaB163.0E+3 cells per wellNAMTT assay1 MOI22% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5422Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI64% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5423Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI40% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5424Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI17% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5425Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI70% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5426Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI60% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5427Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI35% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5428Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoNANANANANANANANAC57Bl6 mice subcutaneous injected for 1.0E+5 B16 cells5.0E+7 pfuNA Reduction in tumor volume to below 0.3 cubic cm compared to control 1.2 cubic cm after 20 daysIntratumoralReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5429Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoNANANANANANANANACBA mice sintramuscularly injected for 5.0E+7 RLS-40 cells5.0E+7 pfuNA Reduction in tumor volume to below 0.2 cubic cm compared to control 0.8 cubic cm after 15 daysIntratumoralReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5457Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoNANANANANANANANABalb/c mice injected with tumor1.0E+4 pfuNA Mice failed to develop cancerSubcutaneousNANANAUS41098983
OV_5458Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoNANANANANANANANABalb/c mice injected with tumor1.0E+5 pfuNA Mice failed to develop cancerSubcutaneousNANANAUS41098983
OV_5459Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoNANANANANANANANABalb/c mice injected with tumor1.0E+6 pfuNA Mice failed to develop cancerSubcutaneousNANANAUS41098983
OV_5682Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 261.8mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5683Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 248.4mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5684Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 216.8mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5685Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 208.8mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5686Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 157.2mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5687Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 280.3mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5688Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 301.9mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5689Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 273.5mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5690Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 243.8mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5691Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 286mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5692Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 267.1mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5693Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 155.6mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5694Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 310.9mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5695Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 416.9mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5696Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 536.1mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5697Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 5550.4mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5698Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 463.4mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5699Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 543.3mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5700Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 320.1mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5701Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 679mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5702Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 660mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5703Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 701.4mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5704Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 761.3mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5705Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 706.6mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5706Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 721.3mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5707Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 476.3mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5708Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 864.1mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5709Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 828.6mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5710Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 978.4mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5711Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 852mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5712Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 985.5mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5713Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 936.1mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5714Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 695mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5715Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 1179.9mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5716Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 897.4mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5717Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 1485mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5718Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 1053mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5719Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 852mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5720Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 606mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5721Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 751mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5722Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 166.7mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5723Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Complete regression in tumor volume after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5724Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 1536.9mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5725Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 962.2mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5726Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 579.2mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5727Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 546.9mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5728Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 720.1mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5729Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 117.8mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5730Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Complete regression in tumor volume after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5731Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 412.9mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5732Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 350.2mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5733Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 341.1mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5734Vaccinia virusGLV-1h82DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 353.4mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5735Vaccinia virusGLV-1h83DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 392.25mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5736Vaccinia virusGLV-1h84DNAPoxviridaeInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 305.6mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5737Vaccinia virusGLV-1h85DNAPoxviridaeInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 350.65mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5738Vaccinia virusGLV-1h86DNAPoxviridaeInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 419.55mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5739Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 750.4mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5740Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 722.3mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5741Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 819.8mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5742Vaccinia virusGLV-1h82DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1081.2mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5743Vaccinia virusGLV-1h83DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1222.25mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968