Detailed description page of Selected OV_ID


OV_5423 details
Primary information
OV_IDOV_5423
Virus Name Vaccinia virus
StrainLIVP-GFP
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeDeletion mutant for tk gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineRussian academy of science
Origin of cell lineHuman cervical carcinoma
Cell lineKB-3-1
Concentration of cell line9
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration1 MOI
In-vitro result40% cell viability after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionReduction production of IL-6 indicating tumor inhibition
Immunogenic effectNA
Clinical trialNA
PMID27538520