The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_4661	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	CAL27	NA	NA	Statistical analysis	0.5 MOI	30% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4662	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	CAL27	NA	NA	Statistical analysis	1 MOI	30% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4663	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.001 MOI	82% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4664	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.005 MOI	60% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4665	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.01 MOI	55% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4666	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.05 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4667	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.1 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4668	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.5 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4669	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	1 MOI	30% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4670	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.001 MOI	100% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4671	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.005 MOI	95% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4672	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.01 MOI	90% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4673	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.05 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4674	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.1 MOI	25% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4675	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.5 MOI	22% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4676	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	1 MOI	20% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4677	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.001 MOI	90% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4678	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.005 MOI	70% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4679	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.01 MOI	65% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4680	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.05 MOI	50% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4681	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.1 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4682	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.5 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4683	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	1 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4684	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.001 MOI	90% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4685	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.005 MOI	82% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4686	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.01 MOI	60% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4687	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.05 MOI	60% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4688	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.1 MOI	50% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4689	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.5 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4690	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	1 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4691	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.001 MOI	90% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4692	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.005 MOI	82% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4693	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.01 MOI	76% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4694	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.05 MOI	62% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4695	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.1 MOI	62% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4696	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.5 MOI	50% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4697	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	1 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4698	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Athymic nude mice subcutaneous xenograft for CAL27 (1.5E+7)	2.0E+6 pfu on day 7 and 16	NA	Mice treated with virus shows delayed tumor growth compared to control, one shows complete tumor regression	Intratumoral	NA	Induce antitumor immune response	NA	27119105
OV_4699	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	SCC-74A	NA	NA	Crystal violet staining	0.5 MOI	38% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4700	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	CAL27	NA	NA	Crystal violet staining	0.5 MOI	42% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4701	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	SCC-1	NA	NA	Crystal violet staining	0.5 MOI	40% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4702	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	SCC-2	NA	NA	Crystal violet staining	0.5 MOI	45% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4703	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	SCC-11A	NA	NA	Crystal violet staining	0.5 MOI	38% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4704	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (0.7 mg/kg/day) an copper chelator showing synergistic effect	No	NA	NA	NA	NA	NA	NA	NA	NA	Athymic nude mice xenograft for UM-SCC-74A (1.5E+7)	2.0E+6 pfu on day 7	NA	Increased in survival time and reduction in tumor volume to below 200 cubic mm comapred to control 700 cubic mm	Intratumoral	NA	Induce antitumor immune response	NA	27119105
OV_4705	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (0.7 mg/kg/day) an copper chelator showing synergistic effect	No	NA	NA	NA	NA	NA	NA	NA	NA	Athymic nude mice xenograft for CAL27 (1.5E+7)	2.0E+6 pfu on day 7	NA	Increased in survival time and reduction in tumor volume to below 500 cubic mm comapred to control 2000 cubic mm	Intratumoral	NA	Induce antitumor immune response	NA	27119105
OV_5188	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copis of gamma 34.5 gene	Yes	No	No	ATCC	Human rhabdosarcoma cell line	RD	1.5E+3 cells per well	NA	Alamar blue assay	0.1 PFU	100% cell viable after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27751346
OV_5189	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copis of gamma 34.5 gene	Yes	No	No	ATCC	Human rhabdosarcoma cell line	RD	1.5E+3 cells per well	NA	Alamar blue assay	1 PFU	50% cell viable after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27751346
OV_5190	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copis of gamma 34.5 gene	Yes	No	No	ATCC	Human rhabdosarcoma cell line	RD	1.5E+3 cells per well	NA	Alamar blue assay	10 PFU	10% cell viable after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27751346
OV_5191	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copis of gamma 34.5 gene	Yes	No	No	ATCC	Human rhabdosarcoma cell line	RD	1.5E+3 cells per well	NA	Alamar blue assay	20 PFU	5% cell viable after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27751346
OV_5192	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copis of gamma 34.5 gene	Yes	No	No	ATCC	human cellosaurus cell line	SJC RH30	1.5E+3 cells per well	NA	Alamar blue assay	0.1 PFU	90% cell viable after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27751346
OV_5193	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copis of gamma 34.5 gene	Yes	No	No	ATCC	human cellosaurus cell line	SJC RH30	1.5E+3 cells per well	NA	Alamar blue assay	1 PFU	90% cell viable after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27751346
OV_5194	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copis of gamma 34.5 gene	Yes	No	No	ATCC	human cellosaurus cell line	SJC RH30	1.5E+3 cells per well	NA	Alamar blue assay	10 PFU	30% cell viable after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27751346
OV_5195	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copis of gamma 34.5 gene	Yes	No	No	ATCC	human cellosaurus cell line	SJC RH30	1.5E+3 cells per well	NA	Alamar blue assay	20 PFU	22% cell viable after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27751346
OV_5256	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	STOSE	4000 cells per well	NA	Alamar blue assay	0.1 PFU	100% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5257	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	STOSE	4000 cells per well	NA	Alamar blue assay	0.33 PFU	70% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5258	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	STOSE	4000 cells per well	NA	Alamar blue assay	1 PFU	15% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5259	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	STOSE	4000 cells per well	NA	Alamar blue assay	3.3 PFU	5% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5260	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	STOSE	4000 cells per well	NA	Alamar blue assay	10 PFU	7% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5261	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	STOSE	4000 cells per well	NA	Alamar blue assay	33 PFU	1% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5262	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	STOSE	4000 cells per well	NA	Alamar blue assay	100 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5263	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	ID8	4000 cells per well	NA	Alamar blue assay	0.1 PFU	100% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5264	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	ID8	4000 cells per well	NA	Alamar blue assay	0.33 PFU	70% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5265	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	ID8	4000 cells per well	NA	Alamar blue assay	1 PFU	50% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5266	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	ID8	4000 cells per well	NA	Alamar blue assay	3.3 PFU	30% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5267	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	ID8	4000 cells per well	NA	Alamar blue assay	10 PFU	10% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5268	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	ID8	4000 cells per well	NA	Alamar blue assay	33 PFU	1% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5269	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	ID8	4000 cells per well	NA	Alamar blue assay	100 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5270	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	Ig10	4000 cells per well	NA	Alamar blue assay	0.1 PFU	100% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5271	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	Ig10	4000 cells per well	NA	Alamar blue assay	0.33 PFU	70% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5272	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	Ig10	4000 cells per well	NA	Alamar blue assay	1 PFU	58% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5273	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	Ig10	4000 cells per well	NA	Alamar blue assay	3.3 PFU	30% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5274	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	Ig10	4000 cells per well	NA	Alamar blue assay	10 PFU	15% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5275	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	Ig10	4000 cells per well	NA	Alamar blue assay	33 PFU	1% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5276	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	Ig10	4000 cells per well	NA	Alamar blue assay	100 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5277	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	MISIIR	4000 cells per well	NA	Alamar blue assay	0.1 PFU	85% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5278	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	MISIIR	4000 cells per well	NA	Alamar blue assay	0.33 PFU	87% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5279	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	MISIIR	4000 cells per well	NA	Alamar blue assay	1 PFU	87% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5280	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	MISIIR	4000 cells per well	NA	Alamar blue assay	3.3 PFU	78% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5281	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	MISIIR	4000 cells per well	NA	Alamar blue assay	10 PFU	62% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5282	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	MISIIR	4000 cells per well	NA	Alamar blue assay	33 PFU	22% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5283	Herpes simplex virus	M002	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Murine ovarian adenocarcinoma cell line	MISIIR	4000 cells per well	NA	Alamar blue assay	100 PFU	20% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5284	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	0.1 PFU	85% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5285	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	0.33 PFU	70% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5286	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	1 PFU	42% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5287	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	3.3 PFU	10% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5288	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	10 PFU	5% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5289	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	33 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5290	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	100 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5291	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HeyA8	4000 cells per well	NA	Alamar blue assay	0.1 PFU	100% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5292	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HeyA8	4000 cells per well	NA	Alamar blue assay	0.33 PFU	98% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5293	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HeyA8	4000 cells per well	NA	Alamar blue assay	1 PFU	95% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5294	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HeyA8	4000 cells per well	NA	Alamar blue assay	3.3 PFU	77% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5295	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HeyA8	4000 cells per well	NA	Alamar blue assay	10 PFU	60% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5296	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HeyA8	4000 cells per well	NA	Alamar blue assay	33 PFU	39% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5297	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HeyA8	4000 cells per well	NA	Alamar blue assay	100 PFU	22% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5298	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	0.1 PFU	100% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5299	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	0.33 PFU	38% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5300	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	1 PFU	10% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5301	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	3.3 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5302	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	10 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340