Detailed description page of Selected OV_ID


OV_5264 details
Primary information
OV_IDOV_5264
Virus Name Herpes simplex virus
StrainM002
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing murine IL-12
Source of cell lineNA
Origin of cell lineMurine ovarian adenocarcinoma cell line
Cell lineID8
Concentration of cell line4000
In-vitro toxicityNA
AssayAlamar blue assay
In-vitro virus concentration0.33 PFU
In-vitro result70% cell viable
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectTumor specific T cell response induced
Clinical trialNA
PMID27784340