Detailed description page of Selected OV_ID


OV_4700 details
Primary information
OV_IDOV_4700
Virus Name Herpes simplex virus
StrainRAMBO
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeAntiangiogenic Vstat120 expressing virus
Virus aloneNo
Virus in combination iwth drug/radiationVirus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman squamous cell carcinoma cell line
Cell lineCAL27
Concentration of cell line0
In-vitro toxicityNA
AssayCrystal violet staining
In-vitro virus concentration0.5 MOI
In-vitro result42% cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectInduce antitumor immune response
Clinical trialNA
PMID27119105