Primary information |
---|
OV_ID | OV_4701 |
Virus Name | Herpes simplex virus |
Strain | RAMBO |
Virus type | DNA |
Virus family | Herpesviridae |
Modification in virus genome | Antiangiogenic Vstat120 expressing virus |
Virus alone | No |
Virus in combination iwth drug/radiation | Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy |
Immune gene induction in virus genome | No |
Source of cell line | NA |
Origin of cell line | Human squamous cell carcinoma cell line |
Cell line | SCC-1 |
Concentration of cell line | 0 |
In-vitro toxicity | NA |
Assay | Crystal violet staining |
In-vitro virus concentration | 0.5 MOI |
In-vitro result | 40% cell viability |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | Induce antitumor immune response |
Clinical trial | NA |
PMID | 27119105 |