Primary information |
---|
OV_ID | OV_4685 |
Virus Name | Herpes simplex virus |
Strain | RAMBO |
Virus type | DNA |
Virus family | Herpesviridae |
Modification in virus genome | Antiangiogenic Vstat120 expressing virus |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | NA |
Origin of cell line | Human squamous cell carcinoma cell line |
Cell line | UM-SCC-1 |
Concentration of cell line | 0 |
In-vitro toxicity | NA |
Assay | Statistical analysis |
In-vitro virus concentration | 0.005 MOI |
In-vitro result | 82% cell viability after 2 days |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | Induce antitumor immune response |
Clinical trial | NA |
PMID | 27119105 |