The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_828	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 240 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	42% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_829	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 300 μg/kg	No	NA	NA	NA	NA	NA	NA	NA	NA	Xenograft BALB/c nu/nu female mice subcutaneously injected with 1.0E+7 × 10⁷ K562 cells in a total volume of 100 μl	1.0E+9 pfu/ml	NA	Reduction in tumor volume to 20 cubic millimeter compared to control 880 cubic millimeter after 30 days	Intratumoral	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_830	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Xenograft BALB/c nu/nu female mice subcutaneously injected with 1.0E+7 × 10⁷ K562 cells in a total volume of 100 μl	1.0E+9 pfu/ml	NA	Reduction in tumor volume to 80 cubic millimeter compared to control 880 cubic millimeter after 30 days	Intratumoral	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_831	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Xenograft BALB/c nu/nu female mice subcutaneously injected with 1.0E+7 × 10⁷ K562 cells in a total volume of 100 μl	1.0E+9 pfu/ml	NA	Reduction in tumor volume to 120 cubic millimeter compared to control 880 cubic millimeter after 30 days	Intratumoral	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_855	Adenovirus	CV890	DNA	Adenoviridae	E1A and E1B gene under control of Adenovirus promoter	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALBc nude mice with Hep3B cell xenograft	1.0E+11 pfu	NA	Complete reduction in tumor nodes	intraperitonial	NA	NA	NA	11522637
OV_856	Adenovirus	CV890	DNA	Adenoviridae	E1A and E1B gene under control of Adenovirus promoter	No	Virus strain in combination with Doxorubicin (10ng/ml)	No	ATCC	Human hepatoma cell line	Hep3B	NA	NA	MTT assay	0.01pfu/cell	90% cancer cell killing after day 9, showing synergism with drug	No	No	NA	No response	NA	NA	NA	NA	11522637
OV_857	Adenovirus	CV890	DNA	Adenoviridae	E1A and E1B gene under control of Adenovirus promoter	Yes	No	No	ATCC	Human hepatoma cell line	Hep3B	NA	NA	MTT assay	0.01pfu/cell	35% cancer cell killing after day 9	No	No	NA	No response	NA	NA	NA	NA	11522637
OV_922	Adenovirus	CNHK-300	DNA	Adenoviridae	Addition of 3 hTERT promoter in E boxes of genome	Yes	No	No	Synthesized	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice	1.0E+9 pfu	NA	Tumor volume decreases to 600 mm3 after 20 days as compared to control	Tail vein injection of virus	NA	NA	NA	15243805
OV_923	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	Onyx pharmaceutical	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice	1.0E+9 pfu	NA	Tumor volume decreases to 200 mm3 after 20 days as compared to control	Tail vein injection of virus	NA	NA	NA	15243805
OV_924	Adenovirus	CNHK-300	DNA	Adenoviridae	Addition of 3 hTERT promoter in E boxes of genome	Yes	No	No	Synthesized	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice	1.0E+9 pfu	NA	Tumor volume decreases to 200 mm3 after 20 days as compared to control	Tail vein injection of virus	NA	NA	NA	15243805
OV_925	Adenovirus	CNHK-300	DNA	Adenoviridae	Addition of 3 hTERT promoter in E boxes of genome	Yes	No	No	Synthesized	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice	5.0E+8 pfu	NA	Tumor volume decreases to 500 mm3 after 20 days as compared to control	Tail vein injection of virus	NA	NA	NA	15243805
OV_926	Adenovirus	CNHK-300	DNA	Adenoviridae	Addition of 3 hTERT promoter in E boxes of genome	Yes	No	No	Synthesized	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice	1.0E+9 pfu	NA	Tumor volume decreases to 400 mm3 after 20 days as compared to control	Tail vein injection of virus	NA	NA	NA	15243805
OV_927	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_928	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_929	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_930	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	All cancer cell survive after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_931	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10 virus particle/cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_932	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	60% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_933	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	60% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_934	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	All cancer cell survive after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_935	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-79	4.0E+3 cells per well	NA	NA	10 virus particle/cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_936	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-79	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_937	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-79	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_938	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-79	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	90% cancer cell survive after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_939	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10 virus particle/cell	90% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_940	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_941	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_942	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_943	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10 virus particle/cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_944	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_945	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	70% cancer cell survival after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_946	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_947	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SMS-SAN	4.0E+3 cells per well	NA	NA	10 virus particle/cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_948	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SMS-SAN	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_949	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SMS-SAN	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	85% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_950	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SMS-SAN	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	90% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_951	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_952	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	90% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_953	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_954	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_955	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_956	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	75% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_957	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	75% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_958	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_959	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10 virus particle/cell	90% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_960	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	90% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_961	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	60% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_962	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	20% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_963	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10 virus particle/cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_964	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_965	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_966	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_967	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-79	4.0E+3 cells per well	NA	NA	10 virus particle/cell	90% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_968	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-79	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	90% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_969	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-79	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	90% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_970	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-79	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_971	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_972	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_973	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_974	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_975	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10 virus particle/cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_976	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_977	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	50% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_978	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	20% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_979	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SMS-SAN	4.0E+3 cells per well	NA	NA	10 virus particle/cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_980	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SMS-SAN	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_981	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SMS-SAN	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	85% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_982	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SMS-SAN	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	90% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_983	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10 virus particle/cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_984	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_985	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_986	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_987	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_988	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	75% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_989	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	75% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_990	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1094	Adenovirus	ZD55-IL-24	DNA	Adenoviridae	Adenovirus expressing ZD55 gene and IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	Human cervical carcinoma cell line	HT-29	2.0E+6 cells per well	NA	MTT assay	5 MOI	60% cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1095	Adenovirus	Ad-IL-24	DNA	Adenoviridae	Adenovirus expressing IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	Human cervical carcinoma cell line	HT-29	2.0E+6 cells per well	NA	MTT assay	5 MOI	20% cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1096	Adenovirus	ZD55-EGFP	DNA	Adenoviridae	Adenovirus expressing EGFP gene	Yes	No	No	Shanghai cell collection	Human cervical carcinoma cell line	HT-29	2.0E+6 cells per well	NA	MTT assay	5 MOI	40% cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1097	Adenovirus	ZD55-IL-24	DNA	Adenoviridae	Adenovirus expressing ZD55 gene and IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	Human cervical carcinoma cell line	SW620	2.0E+6 cells per well	NA	MTT assay	5 MOI	No cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1098	Adenovirus	Ad-IL-24	DNA	Adenoviridae	Adenovirus expressing IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	Human cervical carcinoma cell line	SW620	2.0E+6 cells per well	NA	MTT assay	5 MOI	No cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1099	Adenovirus	ZD55-EGFP	DNA	Adenoviridae	Adenovirus expressing EGFP gene	Yes	No	No	Shanghai cell collection	Human cervical carcinoma cell line	SW620	2.0E+6 cells per well	NA	MTT assay	5 MOI	No cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1100	Adenovirus	ZD55-IL-24	DNA	Adenoviridae	Adenovirus expressing ZD55 gene and IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	Human lung fibroblast cell line	NHLF	2.0E+6 cells per well	NA	MTT assay	5 MOI	No cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1101	Adenovirus	Ad-IL-24	DNA	Adenoviridae	Adenovirus expressing IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	Human lung fibroblast cell line	NHLF	2.0E+6 cells per well	NA	MTT assay	5 MOI	No cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1102	Adenovirus	ZD55-EGFP	DNA	Adenoviridae	Adenovirus expressing EGFP gene	Yes	No	No	Shanghai cell collection	Human lung fibroblast cell line	NHLF	2.0E+6 cells per well	NA	MTT assay	5 MOI	No cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1103	Adenovirus	ZD55-IL-24	DNA	Adenoviridae	Adenovirus expressing ZD55 gene and IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	NA	NA	NA	NA	NA	NA	NA	Athymic BALB/c nude mice xenograft for SW620 cell line	5.0E+8 cells per well	NA	Decrease in tumor volume below 800mm³ as compared to control	Intratumoral injection	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1104	Adenovirus	Ad-IL-24	DNA	Adenoviridae	Adenovirus expressing IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	NA	NA	NA	NA	NA	NA	NA	Athymic BALB/c nude mice xenograft for SW620 cell line	5.0E+8 cells per well	NA	Decrease in tumor volume below 600mm³ as compared to control	Intratumoral injection	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1105	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	Shanghai cell collection	NA	NA	NA	NA	NA	NA	NA	Athymic BALB/c nude mice xenograft for SW620 cell line	5.0E+8 cells per well	NA	Complete reduction in tumor volume	Intratumoral injection	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1170	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.001 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	85% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1171	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.01 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1172	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.1 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	65% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1173	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (10 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	40% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1174	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (100 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1175	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (1000 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1176	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.001 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	65% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1177	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.01 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	55% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1178	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.1 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1179	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (10 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	10% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1180	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (100 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1181	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (1000 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108