Detailed description page of Selected OV_ID


OV_1100 details
Primary information
OV_IDOV_1100
Virus Name Adenovirus
StrainZD55-IL-24
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAdenovirus expressing ZD55 gene and IL-24 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeExpressing IL-24 gene
Source of cell lineShanghai cell collection
Origin of cell lineHuman lung fibroblast cell line
Cell lineNHLF
Concentration of cell line3
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration5 MOI
In-vitro resultNo cell killing after 80 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionApoptosis induction and cspase 3 activation
Immunogenic effectNA
Clinical trialNA
PMID15661558