| Primary information |
|---|
| OV_ID | OV_1100 |
| Virus Name | Adenovirus |
| Strain | ZD55-IL-24 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | Adenovirus expressing ZD55 gene and IL-24 gene |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | Expressing IL-24 gene |
| Source of cell line | Shanghai cell collection |
| Origin of cell line | Human lung fibroblast cell line |
| Cell line | NHLF |
| Concentration of cell line | 3 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 5 MOI |
| In-vitro result | No cell killing after 80 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Apoptosis induction and cspase 3 activation |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 15661558 |