| Primary information |
|---|
| OV_ID | OV_923 |
| Virus Name | Adenovirus |
| Strain | ONYX-015 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | Onyx pharmaceutical |
| Origin of cell line | NA |
| Cell line | NA |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | BALB/c nude mice |
| In-vivo virus concentration | 10â¹ pfu
|
| In-vivo toxicity | NA |
| In-vivo result | Tumor volume decreases to 200 mm3 after 20 days as compared to control |
| Mode of delivery | Tail vein injection of virus |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 15243805 |