Detailed description page of Selected OV_ID


OV_924 details
Primary information
OV_IDOV_924
Virus Name Adenovirus
StrainCNHK-300
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAddition of 3 hTERT promoter in E boxes of genome
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineSynthesized
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice
In-vivo virus concentration10⁹ pfu
In-vivo toxicityNA
In-vivo resultTumor volume decreases to 200 mm3 after 20 days as compared to control
Mode of deliveryTail vein injection of virus
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID15243805