Primary information |
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OV_ID | OV_856 |
Virus Name | Adenovirus |
Strain | CV890 |
Virus type | DNA |
Virus family | Adenoviridae |
Modification in virus genome | E1A and E1B gene under control of Adenovirus promoter |
Virus alone | No |
Virus in combination iwth drug/radiation | Virus strain in combination with Doxorubicin (10ng/ml) |
Immune gene induction in virus genome | No |
Source of cell line | ATCC |
Origin of cell line | Human hepatoma cell line |
Cell line | Hep3B |
Concentration of cell line | 0 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 0.01pfu/cell |
In-vitro result | 90% cancer cell killing after day 9, showing synergism with drug |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 11522637 |