Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2753AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineHuh-71.0E+4 cells per wellNAMTT assay5 MOI30% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2754AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineHuh-71.0E+4 cells per wellNAMTT assay5 MOI20% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2755AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineHuh-7NANANANANABALB/c nude mice xenograft for Huh cell (2.0E+6 cell)7.0E+8 pfuNA Complete regression in tumor volume after 49 daysIntratumoralInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2756AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANAMTT assay0.01 MOINo cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2757AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANAMTT assay0.5 MOIModerate cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2758AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANAMTT assay1 MOIMost of the cells are diedNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2759AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANAMTT assay10 MOIAll cells are diedNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2760AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineHCT-116NANAMTT assay0.01 MOINo cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2761AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineHCT-116NANAMTT assay0.5 MOIModerate cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2762AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineHCT-116NANAMTT assay1 MOIModerate cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2763AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineHCT-116NANAMTT assay10 MOIAll cells are diedNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2764AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineHT-29NANAMTT assay0.01 MOINo cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2765AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineHT-29NANAMTT assay0.5 MOINo cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2766AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineHT-29NANAMTT assay1 MOINo cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2767AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineHT-29NANAMTT assay10 MOIModerate cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2768AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANANANANAnude mice xenograft for Sw620 (1.5E+7 cells)5.0E+8 pfuNA Reduction in tumor volume below 500 as comapred to control 1500mm and increase in median survival timeIntratumoralInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2775AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANACrystal violet staining0.1 MOIModerate cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2776AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANACrystal violet staining0.5 MOIModerate cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2777AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANACrystal violet staining1 MOISignificant cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2778AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANACrystal violet staining5 MOIAll cells was deadNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2779AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANACrystal violet staining10 MOIAll cells was deadNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2780AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANACrystal violet staining0.1 MOINo cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2781AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANACrystal violet staining0.5 MOINo cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2782AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANACrystal violet staining1 MOINo cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2783AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANACrystal violet staining5 MOIModerate cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2784AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANACrystal violet staining10 MOIAll cell was deadNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2785AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANACrystal violet staining0.1 MOINo cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2786AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANACrystal violet staining0.5 MOINo cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2787AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANACrystal violet staining1 MOINo cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2788AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANACrystal violet staining5 MOIModerate cell deathNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2789AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANACrystal violet staining10 MOIAll cell was deadNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2790AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANAMTT assay0.5 MOI90% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2791AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANAMTT assay1 MOI90% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2792AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANAMTT assay2 MOI80% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2793AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANAMTT assay5 MOI80% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2794AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineH-1299NANAMTT assay10 MOI60% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2795AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANAMTT assay0.5 MOI90% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2796AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANAMTT assay1 MOI90% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2797AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANAMTT assay2 MOI80% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2798AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANAMTT assay5 MOI70% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2799AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANAMTT assay10 MOI50% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2800AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANAMTT assay0.5 MOI90% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2801AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANAMTT assay1 MOI80% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2802AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANAMTT assay2 MOI80% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2803AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANAMTT assay5 MOI70% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2804AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineNCI-H460NANAMTT assay10 MOI60% cells are viableNoNoNA No responseNAInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2805AdenovirusAd.sp-E1A-TSLC1DNAAdenoviridaeDeletion of 24bp with in E1A gene and insertion of TSLC1 geneYesNoNoATCCHuman lung cancer cell lineA549NANANANANABALB/c nude mice xenograft for A5495.0E+8 pfuNA Significant reduction in tumor volume and increased in survival rate fro 15% to 87% at day 60IntratumoralInduction of apotosis by virus in cancer cell line as measured by TUNEL assayNANA23503473
OV_2806AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (1.5 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.25 MOI50% cells viabilityNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2807AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (3 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.5 MOI40% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2808AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (4.5 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.75 MOI30% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2809AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (4 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-81 MOI20% cells viabilityNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2810AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (8 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-82 MOI18% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2811AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (16 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-84 MOI10% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2812AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (16 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-468NANANANANABALB/c nude mice xenograft for MDA-MB-468 (5.0E+6 cells)2.0E+5 pfuNA Reduction in tumor volume after 35 daysIntratumoralMitotic arrest and induction of apoptosisNANA23525624
OV_2854AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoShanghai institute of cell biologyGallbladder cancer cell lineGBC-SD1.0E+5 cells per wellNAMTT assay0.1 MOI100% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2855AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoShanghai institute of cell biologyGallbladder cancer cell lineGBC-SD1.0E+5 cells per wellNAMTT assay1 MOI60% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2856AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoShanghai institute of cell biologyGallbladder cancer cell lineGBC-SD1.0E+5 cells per wellNAMTT assay10 MOI10% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2857AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoShanghai institute of cell biologyGallbladder cancer cell lineGBC-SD1.0E+5 cells per wellNAMTT assay100 MOI10% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2858AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB11.0E+5 cells per wellNAMTT assay0.1 MOI100% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2859AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB11.0E+5 cells per wellNAMTT assay1 MOI50% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2860AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB11.0E+5 cells per wellNAMTT assay10 MOI20% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2861AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB11.0E+5 cells per wellNAMTT assay100 MOI10% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2862AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB21.0E+5 cells per wellNAMTT assay0.1 MOI100% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2863AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB21.0E+5 cells per wellNAMTT assay1 MOI40% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2864AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB21.0E+5 cells per wellNAMTT assay10 MOI20% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2865AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB21.0E+5 cells per wellNAMTT assay100 MOI10% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2866AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB2NANANANANABALB/c nude mice xenograft for EH-GB21.0E+9 pfuNA Signficant reduction in tumor volume after day 30 and increase in median survival timeIntratumoralIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23727990
OV_3464AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineA5491.0E+5 cells per wellNAMTS assay100 MOI22% inhibition in tumor inhibitionNoNoNA No responseNANANANA28638457
OV_3465AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineA549-DDPR cisplatin resistant1.0E+5 cells per wellNAMTS assay100 MOI55% inhibition in tumor inhibitionNoNoNA No responseNANANANA28638457
OV_3466AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay25 MOI90% cell viability after 24 hoursNoNoNA No responseNANANANA28638457
OV_3467AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay50 MOI80% cell viability after 24 hoursNoNoNA No responseNANANANA28638457
OV_3468AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay100 MOI70% cell viability after 24 hoursNoNoNA No responseNANANANA28638457
OV_3469AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneNoVirus in combination with cisplatin (4 microgram/ml)NoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay100 MOI50% cell viability after 24 hoursNoNoNA No responseNANANANA28638457
OV_3470AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay25 MOI80% cell viability after 48 hoursNoNoNA No responseNANANANA28638457
OV_3471AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay50 MOI70% cell viability after 48 hoursNoNoNA No responseNANANANA28638457
OV_3472AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay100 MOI62% cell viability after 48 hoursNoNoNA No responseNANANANA28638457
OV_3473AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneNoVirus in combination with cisplatin (4 microgram/ml)NoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay100 MOI42% cell viability after 48 hoursNoNoNA No responseNANANANA28638457
OV_3474AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay25 MOI70% cell viability after 72 hoursNoNoNA No responseNANANANA28638457
OV_3475AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay50 MOI65% cell viability after 72 hoursNoNoNA No responseNANANANA28638457
OV_3476AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay100 MOI52% cell viability after 72 hoursNoNoNA No responseNANANANA28638457
OV_3477AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneNoVirus in combination with cisplatin (4 microgram/ml)NoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay100 MOI40% cell viability after 72 hoursNoNoNA No responseNANANANA28638457
OV_3478AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay25 MOI65% cell viability after 96 hoursNoNoNA No responseNANANANA28638457
OV_3479AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay50 MOI60% cell viability after 96 hoursNoNoNA No responseNANANANA28638457
OV_3480AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay100 MOI55% cell viability after 96 hoursNoNoNA No responseNANANANA28638457
OV_3481AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneNoVirus in combination with cisplatin (4 microgram/ml)NoCell collection centre chinaHuman lung cancer cell lineH2921.0E+5 cells per wellNAMTS assay100 MOI40% cell viability after 96 hoursNoNoNA No responseNANANANA28638457
OV_3482AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay25 MOI90% cell viability after 24 hoursNoNoNA No responseNANANANA28638457
OV_3483AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay50 MOI75% cell viability after 24 hoursNoNoNA No responseNANANANA28638457
OV_3484AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay100 MOI60% cell viability after 24 hoursNoNoNA No responseNANANANA28638457
OV_3485AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneNoVirus in combination with cisplatin (4 microgram/ml)NoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay100 MOI35% cell viability after 24 hoursNoNoNA No responseNANANANA28638457
OV_3486AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay25 MOI85% cell viability after 48 hoursNoNoNA No responseNANANANA28638457
OV_3487AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay50 MOI70% cell viability after 48 hoursNoNoNA No responseNANANANA28638457
OV_3488AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay100 MOI50% cell viability after 48 hoursNoNoNA No responseNANANANA28638457
OV_3489AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneNoVirus in combination with cisplatin (4 microgram/ml)NoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay100 MOI25% cell viability after 48 hoursNoNoNA No responseNANANANA28638457
OV_3490AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay25 MOI80% cell viability after 72 hoursNoNoNA No responseNANANANA28638457
OV_3491AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay50 MOI70% cell viability after 72 hoursNoNoNA No responseNANANANA28638457
OV_3492AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay100 MOI50% cell viability after 72 hoursNoNoNA No responseNANANANA28638457
OV_3493AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneNoVirus in combination with cisplatin (4 microgram/ml)NoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay100 MOI25% cell viability after 72 hoursNoNoNA No responseNANANANA28638457
OV_3494AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay25 MOI75% cell viability after 96 hoursNoNoNA No responseNANANANA28638457
OV_3495AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay50 MOI60% cell viability after 96 hoursNoNoNA No responseNANANANA28638457
OV_3496AdenovirusAdenovirus CRAdsDNAAdenoviridaeNoneYesNoNoCell collection centre chinaHuman lung cancer cell lineH6611.0E+5 cells per wellNAMTS assay100 MOI45% cell viability after 96 hoursNoNoNA No responseNANANANA28638457