Detailed description page of Selected OV_ID


OV_2812 details
Primary information
OV_IDOV_2812
Virus Name Adenovirus
StrainG47-delta
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus strain in combination with palcitaxel (16 nm)
Immune gene induction in virus genomeNo
Source of cell lineSun-sen university cancer centre, china
Origin of cell lineHuman breast cancer cell line
Cell lineMDA-MB-468
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for MDA-MB-468 (5 × 10⁶ cells)
In-vivo virus concentration2 × 10⁵ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume after 35 days
Mode of deliveryIntratumoral
Pathway inductionMitotic arrest and induction of apoptosis
Immunogenic effectNA
Clinical trialNA
PMID23525624