Detailed description page of Selected OV_ID


OV_2790 details
Primary information
OV_IDOV_2790
Virus Name Adenovirus
StrainAd.sp-E1A-TSLC1
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of 24bp with in E1A gene and insertion of TSLC1 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman lung cancer cell line
Cell lineH-1299
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.5 MOI
In-vitro result90% cells are viable
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apotosis by virus in cancer cell line as measured by TUNEL assay
Immunogenic effectNA
Clinical trialNA
PMID23503473