Detailed description page of Selected OV_ID


OV_2854 details
Primary information
OV_IDOV_2854
Virus Name Adenovirus
StrainSG7605-11R-p53
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAddition of p53 gene and 11R CPP
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineShanghai institute of cell biology
Origin of cell lineGallbladder cancer cell line
Cell lineGBC-SD
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.1 MOI
In-vitro result100% cell survival
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionIncrease in apoptosis rate to 67% in cancer cell compared to normal
Immunogenic effectNA
Clinical trialNA
PMID23586034