The total number of records retrieved from this search are 154. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	59% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_2	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	56% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_3	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	49% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_4	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	90% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_5	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_6	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_7	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	70% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_8	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	60% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_9	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	38% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_1406	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with norfloxacin (12.5 microgram/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.5 MOI	70% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1407	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with norfloxacin (12.5 microgram/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	35% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1410	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (6.25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	70% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1411	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (6.25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	70% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1412	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (6.25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	60% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1413	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (12.5pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	70% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1414	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (12.5pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	70% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1415	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (12.5pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	65% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1416	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	70% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1417	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	70% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1418	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	65% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1419	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (50pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	50% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1420	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (50pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	50% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1421	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (50pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	45% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1422	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (100pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	30% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1423	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (100pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	30% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1424	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (100pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	20% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1425	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (12.5pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	42% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1426	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (12.5pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	42% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1427	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (12.5pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	40% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1428	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	20% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1429	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	20% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1430	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (25pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	10% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1431	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (50pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	10% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1432	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (50pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	10% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1433	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (50pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	10% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1434	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (100pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	0.1 MOI	10% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1435	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (100pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	1 MOI	10% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1436	Parovirus	H-1PV	DNA	Paroviridae	None	No	Virus strain in combination with reservatol (100pg/ml)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	NA	NA	MTT assay	10 MOI	10% cell survival	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19301953
OV_1878	Herpes simplex virus	NV1059	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.012 MOI	90% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1879	Herpes simplex virus	NV1060	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.012 MOI	90% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1880	Herpes simplex virus	NV1061	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.012 MOI	90% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1881	Herpes simplex virus	NV1062	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.012 MOI	80% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1882	Herpes simplex virus	NV1063	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.037 MOI	80% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1883	Herpes simplex virus	NV1064	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.037 MOI	80% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1884	Herpes simplex virus	NV1065	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.037 MOI	80% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1885	Herpes simplex virus	NV1066	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.037 MOI	78% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1886	Herpes simplex virus	NV1067	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.11 MOI	90% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1887	Herpes simplex virus	NV1068	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.11 MOI	90% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1888	Herpes simplex virus	NV1069	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.11 MOI	80% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1889	Herpes simplex virus	NV1070	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.11 MOI	60% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1890	Herpes simplex virus	NV1071	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.33 MOI	60% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1891	Herpes simplex virus	NV1072	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.33 MOI	80% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1892	Herpes simplex virus	NV1073	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.33 MOI	65% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1893	Herpes simplex virus	NV1074	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.33 MOI	60% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1894	Herpes simplex virus	NV1075	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	1 MOI	60% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1895	Herpes simplex virus	NV1076	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	1 MOI	60% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1896	Herpes simplex virus	NV1077	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	1 MOI	40% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1897	Herpes simplex virus	NV1078	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	1 MOI	30% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1898	Herpes simplex virus	NV1079	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	3 MOI	60% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1899	Herpes simplex virus	NV1080	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	3 MOI	50% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1900	Herpes simplex virus	NV1081	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	3 MOI	30% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1901	Herpes simplex virus	NV1082	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	3 MOI	20% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1902	Herpes simplex virus	NV1082	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	No	Virus alongwith radiation 2.5 Gy	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	80% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1903	Herpes simplex virus	NV1082	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	No	Virus alongwith radiation 5 Gy	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.2 MOI	35% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1904	Herpes simplex virus	NV1082	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	No	Virus alongwith radiation 10 Gy	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.4 MOI	30% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1905	Herpes simplex virus	NV1082	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	No	Virus alongwith radiation 20 Gy	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.8 MOI	20% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1906	Herpes simplex virus	NV1082	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	No	Virus alongwith radiation 40 Gy	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	1.6 MOI	15% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_2271	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	1 MOI	100% cell death after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2285	Vesicular stomatitis virus	VSV-Delta-M51-GFP	RNA	Rhabdoviridae	Deletion of M51 gene and insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	1 MOI	5% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2299	Vesicular stomatitis virus	VSV-p1-GFP	RNA	Rhabdoviridae	Insertion of P gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	1 MOI	98% cell death after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2313	Vesicular stomatitis virus	Sev-GFP	RNA	Rhabdoviridae	Insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	1 MOI	10% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2327	Vesicular stomatitis virus	RSV-GFP	RNA	Rhabdoviridae	Insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	1 MOI	20% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2341	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	5% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2355	Vesicular stomatitis virus	VSV-Delta-M51-GFP	RNA	Rhabdoviridae	Deletion of M51 gene and insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	5% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2369	Vesicular stomatitis virus	VSV-p1-GFP	RNA	Rhabdoviridae	Insertion of P gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	5% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2383	Vesicular stomatitis virus	Sev-GFP	RNA	Rhabdoviridae	Virus expressing GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	40% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2397	Vesicular stomatitis virus	RSV-GFP	RNA	Rhabdoviridae	Virus expressing GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	80% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2409	Vesicular stomatitis virus	VSV-Delta-M51-GFP	RNA	Rhabdoviridae	Deletion of M51 gene and insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	PANC-1	NA	NA	NA	NA	NA	Athymic mice xenograft for MIA PANC-1 cell line	5 × 10⁷ pfu	NA	Reduction in tumor weight below 200 mg after 25 days	Intratumoral	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2417	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	100% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2418	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	100% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2419	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	90% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2420	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	20% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2421	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	100% cell killing after day 9	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2457	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	100% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2458	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	90% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2459	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	50% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2460	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	10% cell survival after day 7	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2461	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	100% cell death after day 9	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2495	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	100% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2496	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	30% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2497	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	95% cell killing after day 5	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2498	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	100% cell killing after day 5	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2526	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells)	2.0E+6 pfu	NA	Decrease in tumor volume below 2 after 34 days	Intratumoral	NA	NA	NA	22258815
OV_2527	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells)	2.0E+6 pfu	NA	Decrease in tumor volume below 2 after 34 days	Intravenous	NA	NA	NA	22258815
OV_3419	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.01 MOI	No cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3420	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.05 MOI	80% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3421	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.1 MOI	80% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3422	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.5 MOI	50% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3423	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	1 MOI	30% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3430	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with gemcitabine (7.5 × 10⁻² micromolar) after 1 hour	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.1 MOI	75% of the tumor cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3431	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with gemcitabine (7.5 × 10⁻² micromolar) after 24 hour	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.1 MOI	75% of the tumor cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3438	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (5 × 10⁻³ micromolar) after 1 hour	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.1 MOI	50% of the tumor cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3439	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (5 × 10⁻³ micromolar) after 24 hour	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.1 MOI	60% of the tumor cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3458	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.075 MOI	75% cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3459	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.1 MOI	75% cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3460	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	SRB assay	0.125 MOI	72% cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3461	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	CTB assay	0.075 MOI	72% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3462	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	CTB assay	0.1 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3463	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	PANC-1	4.0E+4 cells per well	NA	CTB assay	0.125 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3741	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.0001 MOI	100% cell survival after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3742	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.001 MOI	100% cell survival after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3743	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.01 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3744	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	1 MOI	20% cell survival after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3745	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	2 MOI	100% cell killing after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3746	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	3 MOI	100% cell killing after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3759	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (1 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3760	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (1 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	50% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3761	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (5 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3762	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (5 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	20% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_4136	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	No	Virus in combination with drug Gemcitabine (1000 ng/ml)	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	1 vp/cell	100% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4137	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	No	Virus in combination with drug Gemcitabine (10000 ng/ml)	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	10 vp/cell	100% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4138	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	No	Virus in combination with drug Gemcitabine (100000 ng/ml)	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	100 vp/cell	70% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4139	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	No	Virus in combination with drug Gemcitabine (1000000 ng/ml)	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	1000 vp/cell	20% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4140	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	No	Virus in combination with drug Gemcitabine (10000000 ng/ml)	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	10000 vp/cell	100% cancer cell killing	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4141	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	No	Virus in combination with drug Gemcitabine (100000000 ng/ml)	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	100000 vp/cell	100% cancer cell killing	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4142	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	1 vp/cell	100% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4143	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	10 vp/cell	100% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4144	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	100 vp/cell	100% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4145	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	1000 vp/cell	40% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4146	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	10000 vp/cell	10% cell survival	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4147	Adenovirus	AduPARE1A	DNA	Adenoviridae	Addition of E1A gene upstream of uPAR promoter	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	3.0E+3 cells per well	NA	MTT assay	100000 vp/cell	100% cancer cell killing	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26227809
OV_4297	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreas epithelioid carcinoma	PANC-1	4000 cells per well	NA	MTT assay	10 pfu	49.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_5082	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	No	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	1 MOI	100% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5083	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	No	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	2 MOI	80% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5084	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	No	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	4 MOI	70% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5085	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	No	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	8 MOI	60% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5086	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	No	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	16 MOI	60% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5087	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	Virus in combination with SNS032 5ng/ml	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	1 MOI	70% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5088	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	Virus in combination with SNS032 10ng/ml	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	2 MOI	60% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5089	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	Virus in combination with SNS032 20ng/ml	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	4 MOI	50% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5090	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	Virus in combination with SNS032 40ng/ml	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	8 MOI	40% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5091	Adenovirus	ZD-55-TRAIl-IETD-smac	DNA	Adenoviridae	Addition of TRAIL and smac gene via IETD linker	Yes	Virus in combination with SNS032 80ng/ml	Virus expressing TRAIL gene	Shanghai cell collection	Human pancreatic cancer cell line	PANC-1	1.0E+4 cells per well	NA	MTT assay	16 MOI	30% cell viability	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28440486
OV_5351	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	28315430
OV_5352	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	28315430
OV_5353	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	No	Virus in combination with gemcitabine 0.01 micromoar	No	ATCC	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	28315430
OV_5354	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	No	Virus in combination with gemcitabine 0.01 micromoar	No	ATCC	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	68% cell viability after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	28315430
OV_5355	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	No	Virus in combination with gemcitabine 0.05 micromoar	No	ATCC	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	65% cell viability after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	28315430
OV_5356	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	No	Virus in combination with gemcitabine 0.05 micromoar	No	ATCC	Human pancreatic cancer cell line	PANC-1	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	50% cell viability after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	28315430
OV_5560	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	Human pancreatic cell line	PANC-1	1.0E+5 cells per well	NA	NA	1 MOI	Significant death of cancer cell line after 72 hours	No	No	NA	No response	NA	Induction of apoptosis by virus infection	NA	NA	US7270812B2
OV_5565	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	NA	Human pancreatic cell line	PANC-1	1.0E+5 cells per well	NA	NA	1 MOI	Significant death of cancer cell line after 72 hours	No	No	NA	No response	NA	Induction of apoptosis by virus infection	NA	NA	US7270812B2
OV_5570	Sindbis virus	AR339	RNA	Togaviridae	None	No	Sindbis virus in combination with Reovirus	No	NA	Human pancreatic cell line	PANC-1	1.0E+5 cells per well	NA	NA	1 MOI	Enhancer cytolytic effect in combination after 72 hours	No	No	NA	No response	NA	Induction of apoptosis by virus infection	NA	NA	US7270812B2
OV_5592	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human pancreatic carcinoma cell line	PANC-1	80% confluency	NA	MTT assay	3 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5902	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	5E+5 pfu	NA	LDH release assay	0.1 MOI	50% of cancer cell death occurs after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5904	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984