Detailed description page of Selected OV_ID


OV_3742 details
Primary information
OV_IDOV_3742
Virus Name Vaccinia virus
Strainvv-smac
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeInsertion of smac and gpt gene in TK
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineType culture collection of china
Origin of cell lineHuman pancreatic cancer cell line
Cell linePANC-1
Concentration of cell line5
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.001 MOI
In-vitro result100% cell survival after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce apoptosis in cancer cell
Immunogenic effectNA
Clinical trialNA
PMID30365143