Detailed description page of Selected OV_ID


OV_3463 details
Primary information
OV_IDOV_3463
Virus Name Vaccinia virus
StrainGLV-1h68
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeInsertion of three gene beta-glucouronidase, galactosidase and GFP
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman pancreatic adenocarcinoma cell line
Cell linePANC-1
Concentration of cell line4
In-vitro toxicityNA
AssayCTB assay
In-vitro virus concentration0.125 MOI
In-vitro result70% cell viability after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID28607950