Detailed description page of Selected OV_ID


OV_4138 details
Primary information
OV_IDOV_4138
Virus Name Adenovirus
StrainAduPARE1A
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAddition of E1A gene upstream of uPAR promoter
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with drug Gemcitabine (100000 ng/ml)
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman pancreatic cancer cell line
Cell linePANC-1
Concentration of cell line3
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration100 vp/cell
In-vitro result70% cell survival
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce apoptosis process leads to cancer cell death
Immunogenic effectNA
Clinical trialNA
PMID26227809