Detailed description page of Selected OV_ID


OV_1895 details
Primary information
OV_IDOV_1895
Virus Name Herpes simplex virus
StrainNV1076
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman pancreatic cancer cell line
Cell linePANC-1
Concentration of cell line2
In-vitro toxicityNA
AssayLDH release assay
In-vitro virus concentration1 MOI
In-vitro result60% cell survival after day 3
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis by the virus
Immunogenic effectNA
Clinical trialNA
PMID20629009