The total number of records retrieved from this search are 150. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_568	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with PKA catalytic subunit siRNA and scramble siRNA (siPKA-1)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	10 PFU/cell	62% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	NA	NA	27374176
OV_569	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with PKA catalytic subunit siRNA and scramble siRNA (siPKA-2)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	10 PFU/cell	57% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	NA	NA	27374176
OV_570	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with PKA catalytic subunit siRNA and scramble siRNA (siPKA-3)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	10 PFU/cell	65% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	NA	NA	27374176
OV_571	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	10 PFU/cell	50% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_572	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.001 PFU/cell	70% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_573	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.001 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_574	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.01 PFU/cell	39% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_575	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.01 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_576	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.1 PFU/cell	22% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_577	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.1 PFU/cell	92% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_578	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	1 PFU/cell	20% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_579	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	1 PFU/cell	80% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_580	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	20% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_581	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	10 PFU/cell	75% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_592	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1001)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_593	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1002)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	70% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_594	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1003)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	90% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_595	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1001) and with H89(10 μM)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	60% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_596	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1002) and with H89(10 μM)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	45% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_597	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1003) and with H89(10 μM)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	75% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_598	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with ESI-09 and with H89(10 μM)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	0.1 PFU/cell	60% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	ESI-09 abrogates the activities of Caspase-3/9/8 induced by H89/M1 combination treatment.	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_599	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with ESI-09	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	0.1 PFU/cell	80% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	ESI-09 abrogates the activities of Caspase-3/9/8 induced by H89/M1 combination treatment.	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_1156	Herpes simplex virus	NV1020	DNA	Herpesviridae	None	Yes	No	No	ATCC	Colon carcinoma cell line	HCT-116	1.25E+3 cells per well	NA	WST-1 assay	1 × 10⁶ pfu/ml	70% cell killing	No	No	NA	No response	NA	NA	NA	NA	17117895
OV_2760	Adenovirus	ZD55-lipocalin2	DNA	Adenoviridae	Deletion of E1B55 gene and insertion of lipocalin2 gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HCT-116	NA	NA	MTT assay	0.01 MOI	No cell death	No	No	NA	No response	NA	Inducing apoptosis and decreasing microvessel density of tumor	NA	NA	23464854
OV_2761	Adenovirus	ZD55-lipocalin2	DNA	Adenoviridae	Deletion of E1B55 gene and insertion of lipocalin2 gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HCT-116	NA	NA	MTT assay	0.5 MOI	Moderate cell death	No	No	NA	No response	NA	Inducing apoptosis and decreasing microvessel density of tumor	NA	NA	23464854
OV_2762	Adenovirus	ZD55-lipocalin2	DNA	Adenoviridae	Deletion of E1B55 gene and insertion of lipocalin2 gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HCT-116	NA	NA	MTT assay	1 MOI	Moderate cell death	No	No	NA	No response	NA	Inducing apoptosis and decreasing microvessel density of tumor	NA	NA	23464854
OV_2763	Adenovirus	ZD55-lipocalin2	DNA	Adenoviridae	Deletion of E1B55 gene and insertion of lipocalin2 gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HCT-116	NA	NA	MTT assay	10 MOI	All cells are died	No	No	NA	No response	NA	Inducing apoptosis and decreasing microvessel density of tumor	NA	NA	23464854
OV_2819	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2820	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	20% cell survival after 48 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2821	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2834	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	1.0E+6 cells per well	NA	MTT assay	1 MOI	60% cell survival after 24 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2835	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	1.0E+6 cells per well	NA	MTT assay	1 MOI	40% cell survival after 48 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2836	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	1.0E+6 cells per well	NA	MTT assay	1 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2843	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HCT-116 (5.0E+6 cells)	5.0E+6 pfu	NA	Significant reduction in tumor volume after 42 days	Intratumoral	NA	NA	NA	23531320
OV_2972	Tanapoxvirus	TPV-delta66R-mMCP-1	DNA	Poxviridae	Deletion of 66R and insertion of MCP-1 gene	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Nude Foxn1 mice xenograft for HCT-116 (5.0E+6)	5.0E+6 pfu	NA	Reduction in tumor volume to 50mm after 36 days	Intratumoral	NA	Triggers activation of Ipaf inflamosome, IL-beta, TNF-alpha, IL-6 and IL-8	NA	25887490
OV_2973	Tanapoxvirus	TPV-delta66R/flic	DNA	Poxviridae	Deletion of 66R and insertion of flic gene	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Nude Foxn1 mice xenograft for HCT-116 (5.0E+6)	5 × 10⁶ pfu	NA	Reduction in tumor volume to below 50mm after 36 days	Intratumoral	NA	Triggers activation of Ipaf inflamosome, IL-beta, TNF-alpha, IL-6 and IL-8	NA	25887490
OV_2974	Tanapoxvirus	TPV-delta66R	DNA	Poxviridae	Deletion of 66R	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Nude Foxn1 mice xenograft for HCT-116 (5.0E+6)	5 × 10⁶ pfu	NA	Reduction in tumor volume to 50mm after 36 days	Intratumoral	NA	Triggers activation of Ipaf inflamosome, IL-beta, TNF-alpha, IL-6 and IL-8	NA	25887490
OV_2975	Tanapoxvirus	TPV-delta2L	DNA	Poxviridae	Deletion of 2L gene	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Nude Foxn1 mice xenograft for HCT-116 (5.0E+6)	5 × 10⁶ pfu	NA	Reduction in tumor volume to below 50mm after 36 days	Intratumoral	NA	Triggers activation of Ipaf inflamosome, IL-beta, TNF-alpha, IL-6 and IL-8	NA	25887490
OV_2976	Tanapoxvirus	TPV-delta2L/delta66R/flic	DNA	Poxviridae	Deletion of 66R, 2L and insertion of flic gene	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Nude Foxn1 mice xenograft for HCT-116 (5.0E+6)	5 × 10⁶ pfu	NA	Reduction in tumor volume to below 50mm after 36 days	Intratumoral	NA	Triggers activation of Ipaf inflamosome, IL-beta, TNF-alpha, IL-6 and IL-8	NA	25887490
OV_2982	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2983	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	98% cell survival after 48 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2984	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	80% cell survival after 72 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2985	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	45% cell survival after 96 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2986	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	5% cell survival after 120 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2987	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	80% cell survival after 24 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2988	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	30% cell survival after 48 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2989	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2990	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	5% cell survival after 96 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2991	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	100% cell death after 120 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3002	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HCT-116 (2.0E+6 cells)	1.0E+5 pfu	NA	Complete regression in tumor volume after 55 days	Intratumoral	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3004	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	No	Virus in combination with I-131	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HCT-116 (2.0E+6 cells)	1.0E+4 pfu	NA	Reduction in tumor volume below 100mm after 55 days	Intravenous	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3072	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	30% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3073	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	5% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3074	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	1% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3102	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	30% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3103	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	10% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3104	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	1% cell death	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3117	Vaccinia virus	Vaccinia virus deltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	ATCC	Human colon cancer cell line	HCT-116	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 500 mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_3118	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	ATCC	Human colon cancer cell line	HCT-116	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 100 mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_3675	Measles virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	5000 cells per well	NA	MTT assay	1 MOI	80% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3676	Measles virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	5000 cells per well	NA	MTT assay	1 MOI	70% cell viability after day 6	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3691	Mumps virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	5000 cells per well	NA	MTT assay	1 MOI	80% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3692	Mumps virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human colon cancer cell line	HCT-116	5000 cells per well	NA	MTT assay	1 MOI	75% cell viability after day 6	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3707	Measles and mumps virus	wild type	RNA	Paramyxoviridae	None	No	Measles virus in combination with mumps virus	No	ATCC	Human colon cancer cell line	HCT-116	5000 cells per well	NA	MTT assay	1 MOI	80% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3708	Measles and mumps virus	wild type	RNA	Paramyxoviridae	None	No	Measles virus in combination with mumps virus	No	ATCC	Human colon cancer cell line	HCT-116	5000 cells per well	NA	MTT assay	1 MOI	50% cell viability after day 6	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3775	Newcastle disease virus	NDVstrain 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	30% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3776	Newcastle disease virus	NDVstrain 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	38% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3777	Newcastle disease virus	NDVstrain 320	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	44% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3778	Newcastle disease virus	NDVstrain 373	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	55% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3779	Newcastle disease virus	NDVstrain 321	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	58% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3780	Newcastle disease virus	NDVstrain 264	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	58% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3781	Newcastle disease virus	NDVstrain 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	62% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3782	Newcastle disease virus	NDVstrain 880	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	65% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3783	Newcastle disease virus	NDVstrain 14	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	70% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3784	Newcastle disease virus	NDVstrain 329	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	70% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3785	Newcastle disease virus	NDVstrain 485	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	80% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3786	Newcastle disease virus	NDVstrain 718	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	82% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3787	Newcastle disease virus	NDVstrain 53	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	85% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3788	Newcastle disease virus	NDVstrain 52	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	85% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3789	Newcastle disease virus	NDVstrain 746	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	85% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3790	Newcastle disease virus	NDVstrain 12	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	85% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3791	Newcastle disease virus	NDVstrain 49	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	90% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3792	Newcastle disease virus	NDVstrain 753	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	90% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3793	Newcastle disease virus	NDVstrain 777	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	95% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3794	Newcastle disease virus	NDVstrain 789	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	95% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3795	Newcastle disease virus	NDVstrain 27	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	95% cells viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3796	Newcastle disease virus	NDVstrain 48	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	100% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3797	Newcastle disease virus	NDVstrain 389	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	100% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3798	Newcastle disease virus	NDVstrain AD	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	100% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3799	Newcastle disease virus	NDVstrain 922	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	100% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3800	Newcastle disease virus	NDVstrain 945	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	100% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3801	Newcastle disease virus	NDVstrain 429	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	100% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3802	Newcastle disease virus	NDVstrain 339	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	100% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3887	Newcastle disease virus	NDVstrain 264	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	63% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3888	Newcastle disease virus	NDVstrain 264	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	60% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3889	Newcastle disease virus	NDVstrain 264	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	58% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3890	Newcastle disease virus	NDVstrain 320	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	69% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3891	Newcastle disease virus	NDVstrain 320	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	55% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3892	Newcastle disease virus	NDVstrain 320	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	43% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3893	Newcastle disease virus	NDVstrain 321	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	75% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3894	Newcastle disease virus	NDVstrain 321	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	67% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3895	Newcastle disease virus	NDVstrain 321	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	58% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3896	Newcastle disease virus	NDVstrain 373	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	64% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3897	Newcastle disease virus	NDVstrain 373	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	59% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3898	Newcastle disease virus	NDVstrain 373	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	54% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3899	Newcastle disease virus	NDVstrain 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	57% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3900	Newcastle disease virus	NDVstrain 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	41% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3901	Newcastle disease virus	NDVstrain 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	37% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3902	Newcastle disease virus	NDVstrain 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	37% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3903	Newcastle disease virus	NDVstrain 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	32% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3904	Newcastle disease virus	NDVstrain 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	29% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3905	Newcastle disease virus	NDVstrain 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	68% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3906	Newcastle disease virus	NDVstrain 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	65% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3907	Newcastle disease virus	NDVstrain 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3992	Newcastle disease virus	NDVwild 264	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3993	Newcastle disease virus	NDVwild 264	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	60% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3994	Newcastle disease virus	NDVwild 264	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	58% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4004	Newcastle disease virus	NDVwild 320	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	70% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4005	Newcastle disease virus	NDVwild 320	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	58% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4006	Newcastle disease virus	NDVwild 320	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	42% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4016	Newcastle disease virus	NDVwild 321	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	70% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4017	Newcastle disease virus	NDVwild 321	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	65% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4018	Newcastle disease virus	NDVwild 321	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	58% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4028	Newcastle disease virus	NDVwild 373	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4029	Newcastle disease virus	NDVwild 373	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	60% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4030	Newcastle disease virus	NDVwild 373	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	58% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4040	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4041	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	42% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4042	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4052	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4053	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	35% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4054	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	30% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4064	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	68% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4065	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	65% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4066	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4313	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	10 pfu	81.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4343	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4344	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.01 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4345	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.1 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4346	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	10 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4347	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	100 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4348	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4349	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.01 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4350	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.1 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4351	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	10 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4352	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	100 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4358	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 100 micromoalr	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.001 MOI	40% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4359	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 200 micromoalr	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.01 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4360	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 400 micromoalr	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.1 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_5069	Avian orthoreovirus	ARV-PB1	RNA	Reoviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	1.0E+3 cells per well	NA	Crystal violet staining	10 MOI	100% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28441762