Detailed description page of Selected OV_ID


OV_2987 details
Primary information
OV_IDOV_2987
Virus Name Poxvirus
StrainCF33-hNIS
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeInsertion of gene encoding human hNIS
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman colorectal cancer cell line
Cell lineHCT-116
Concentration of cell line3
In-vitro toxicityNA
AssayCell viability assay kit
In-vitro virus concentration1 MOI
In-vitro result80% cell survival after 24 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionImmunogenicity followed by virus induced cell death
Immunogenic effectNA
Clinical trialNA
PMID31061881