Detailed description page of Selected OV_ID


OV_4360 details
Primary information
OV_IDOV_4360
Virus Name Alphavirus
StrainM1
Virus typeRNA
Virus familyTogaviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with dbcAMP 400 micromoalr
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman colorectal carcinoma
Cell lineHCT-116
Concentration of cell line4000
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.1 MOI
In-vitro result30% cell viability after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis
Immunogenic effectNA
Clinical trialNA
PMID26373347