Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 171. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_59AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (YB-1 gene knockdown)NANACrystal violet staining0.01 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_60AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (YB-1 gene knockdown)NANACrystal violet staining0.1 MOI90% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_61AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (YB-1 gene knockdown)NANACrystal violet staining1 MOI40% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_62AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (YB-1 gene knockdown)NANACrystal violet staining10 MOI2% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_63AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining0.001 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_64AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining0.01 MOI90% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_65AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining0.1 MOI60% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_66AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining1 MOI4% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_67AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining10 MOI1% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_68AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining0.001 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_69AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining0.01 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_70AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining0.1 MOI96% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_71AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining1 MOI80% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_72AdenovirusAd5WS1DNAAdenoviridaeE1B55K-deleted mutant driven by the E1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining10 MOI20% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_73AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining0.01 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_74AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining0.1 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_75AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining1 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_76AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining10 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_77AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining0.01 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_78AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining0.1 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_79AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining1 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_80AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining10 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_81AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (YB-1 gene knockdown)NANACrystal violet staining0.01 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_82AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (YB-1 gene knockdown)NANACrystal violet staining0.1 MOI85% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_83AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (YB-1 gene knockdown)NANACrystal violet staining1 MOI35% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_84AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (YB-1 gene knockdown)NANACrystal violet staining10 MOI1% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_85AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining0.001 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_86AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining0.01 MOI90% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_87AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining0.1 MOI20% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_88AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining1 MOI2% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_89AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged YB-1 gene overexpressed)NANACrystal violet staining10 MOI1% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_90AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining0.001 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_91AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining0.01 MOI100% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_92AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining0.1 MOI94% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_93AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining1 MOI75% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_94AdenovirusAd5GS3DNAAdenoviridaeE1B55K-deleted mutant driven by the MDR1 promoterYesNoNoNAHuman breast cancer lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)NANACrystal violet staining10 MOI16% cancer cell viabilityNoNoNA No responseNANANANA26515462
OV_2222Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI100% cell survival after day 1NoNoNA No responseNACaspase activationNANA22108767
OV_2223Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI100% cell survival after day 2NoNoNA No responseNACaspase activationNANA22108767
OV_2224Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI70% cell survival after day 3NoNoNA No responseNACaspase activationNANA22108767
OV_2225Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI40% cell survival after day 4NoNoNA No responseNACaspase activationNANA22108767
OV_2226Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI20% cell death after day 5NoNoNA No responseNACaspase activationNANA22108767
OV_2227Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI90% cell survival after day 1NoNoNA No responseNACaspase activationNANA22108767
OV_2228Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI60% cell survival after day 2NoNoNA No responseNACaspase activationNANA22108767
OV_2229Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI30% cell survival after day 3NoNoNA No responseNACaspase activationNANA22108767
OV_2230Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI10% cell survival after day 4NoNoNA No responseNACaspase activationNANA22108767
OV_2231Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoState key laboratory of oncology ChinaHuman breast cancer cell lineMCF-71.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI100% cell death after day 5NoNoNA No responseNACaspase activationNANA22108767
OV_2634AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseYesNoNoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOI90% cell survival after 3 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2635AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseYesNoNoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOI60% cell survival after 6 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2640AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOI60% cell survival after 3 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2641AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOI30% cell survival after 6 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2642AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOI60% cell survival after 3 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2643AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOI20% cell survival after 6 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2654AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay0.001 MOI80% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2655AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay0.01 MOI80% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2656AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay0.1 MOI60% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2657AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOI50% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2658AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay10 MOI30% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2659AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay0.001 MOI70% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2660AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay0.01 MOI70% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2661AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay0.1 MOI30% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2662AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOI20% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2663AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMCF-71.0E+4 cells per wellNAMTT assay10 MOI10% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2806AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (1.5 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.25 MOI50% cells viabilityNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2807AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (3 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.5 MOI40% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2808AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (4.5 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.75 MOI30% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_3006Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay0.01 MOI100% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3007Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay0.1 MOI90% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3008Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay1 MOI80% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3009Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay3 MOI75% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3010Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3011Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay0.01 MOI100% cell viability after 120 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3012Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay0.1 MOI75% cell viability after 120 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3013Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay1 MOI50% cell viability after 120 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3014Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay3 MOI30% cell viability after 120 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3015Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAMTT assay10 MOI5% cell viability after 120 hoursNoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3016Measles viruswild typeRNAParamyxoviridaeNoneNoCPT (10nM) drug administered first and then virusNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.20 fraction of cell affected, shows antagonism (CI = 1.34)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3017Measles viruswild typeRNAParamyxoviridaeNoneNoVirus added first and then drug CPT drug administered (10nM)NoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.19 fraction of cell affected, shows antagonism (CI = 1.66)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3018Measles viruswild typeRNAParamyxoviridaeNoneNoVirus and drug (10nM) co-administeredNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.56 fraction of cell affected, shows synergism (CI = 0.11)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3019Measles viruswild typeRNAParamyxoviridaeNoneNoCPT (30nM) drug administered first and then virusNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.25 fraction of cell affected, shows antagonism (CI = 1.75)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3020Measles viruswild typeRNAParamyxoviridaeNoneNoVirus added first and then drug CPT drug administered (30nM)NoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.19 fraction of cell affected, shows antagonism (CI = 2.02)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3021Measles viruswild typeRNAParamyxoviridaeNoneNoVirus and drug (30nM) co-administeredNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.65 fraction of cell affected, shows synergism (CI = 0.21)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3022Measles viruswild typeRNAParamyxoviridaeNoneNoCPT (50nM) drug administered first and then virusNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.37 fraction of cell affected, shows antagonism (CI = 1.2)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3023Measles viruswild typeRNAParamyxoviridaeNoneNoVirus added first and then drug CPT drug administered (50nM)NoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.13 fraction of cell affected, shows antagonism (CI = 5.12)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3024Measles viruswild typeRNAParamyxoviridaeNoneNoVirus and drug (50nM) co-administeredNoUniversity of toronto, canadaHuman breast adenocarcinomaMCF-71.0E+4 cells per wellNAChou-talay method0.1 MOI0.69 fraction of cell affected, shows synergism (CI = 0.31)NoNoNA No responseNAInduction of apoptosisNANA31043633
OV_3621Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI60% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3622Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI20% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3635Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI100% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3636Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI100% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3649Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI70% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3650Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI18% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3714EnterovirusECHO-7 virus stain RigvirRNAPicornaviridaeNoneYesNoNoPublic health englandHuman breast cancer cell lineMCF-7NANALive cell imaging system1% virus concentration27% cell viabilityNoNoNA No responseNANANANA29581783
OV_3721EnterovirusECHO-7 virus stain RigvirRNAPicornaviridaeNoneYesNoNoPublic health englandHuman breast cancer cell lineMCF-7NANALive cell imaging system10% virus concentration24% cell viabilityNoNoNA No responseNANANANA29581783
OV_3859Newcastle disease virusNDVstrain 320RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU67% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3860Newcastle disease virusNDVstrain 27RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU67% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3861Newcastle disease virusNDVstrain 852RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU67% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3862Newcastle disease virusNDVstrain ADRNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU70% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3863Newcastle disease virusNDVstrain 860RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU72% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3864Newcastle disease virusNDVstrain 753RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU74% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3865Newcastle disease virusNDVstrain 429RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU75% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3866Newcastle disease virusNDVstrain 718RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU82% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3867Newcastle disease virusNDVstrain 770RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU84% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3868Newcastle disease virusNDVstrain 264RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU84% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3869Newcastle disease virusNDVstrain 777RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU84% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3870Newcastle disease virusNDVstrain 776RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU86% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3871Newcastle disease virusNDVstrain 922RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU86% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3872Newcastle disease virusNDVstrain 14RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU90% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3873Newcastle disease virusNDVstrain 49RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU90% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3874Newcastle disease virusNDVstrain 321RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU92% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3875Newcastle disease virusNDVstrain 945RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU94% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3876Newcastle disease virusNDVstrain 52RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU94% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3877Newcastle disease virusNDVstrain 48RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU94% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3878Newcastle disease virusNDVstrain 329RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU99% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3879Newcastle disease virusNDVstrain 746RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU99% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3880Newcastle disease virusNDVstrain 53RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU100% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3881Newcastle disease virusNDVstrain 389RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU100% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3882Newcastle disease virusNDVstrain 12RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU100% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3883Newcastle disease virusNDVstrain 373RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU100% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3884Newcastle disease virusNDVstrain 465RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU100% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3885Newcastle disease virusNDVstrain 769RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU100% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3886Newcastle disease virusNDVstrain 339RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU100% cell viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4001Newcastle disease virusNDVwild 264RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay2 HAU82% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4002Newcastle disease virusNDVwild 264RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay8 HAU82% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4003Newcastle disease virusNDVwild 264RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU82% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4013Newcastle disease virusNDVwild 320RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay2 HAU100% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4014Newcastle disease virusNDVwild 320RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay8 HAU100% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4015Newcastle disease virusNDVwild 320RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU70% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4025Newcastle disease virusNDVwild 321RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay2 HAU95% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4026Newcastle disease virusNDVwild 321RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay8 HAU70% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4027Newcastle disease virusNDVwild 321RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU95% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4037Newcastle disease virusNDVwild 373RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay2 HAU100% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4038Newcastle disease virusNDVwild 373RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay8 HAU100% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4039Newcastle disease virusNDVwild 373RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU100% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4049Newcastle disease virusNDVwild 770RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay2 HAU79% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4050Newcastle disease virusNDVwild 770RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay8 HAU80% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4051Newcastle disease virusNDVwild 770RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU80% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4061Newcastle disease virusNDVwild 852RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay2 HAU62% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4062Newcastle disease virusNDVwild 852RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay8 HAU62% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4063Newcastle disease virusNDVwild 852RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU62% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4073Newcastle disease virusNDVwild 776RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay2 HAU90% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4074Newcastle disease virusNDVwild 776RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay8 HAU90% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4075Newcastle disease virusNDVwild 776RNAParamyxoviridaeNoneYesNoNoRussian academy of science, RussiaHuman breast cancer adenocarcinoma cell lineMCF-710000 cells per wellNAMTT assay16 HAU80% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4081AdenovirusAdenovirus ZD55DNAAdenoviridaeVirus encoded with drosophila dNK geneNoVirus in combination with drug BVDU(10mg/kg)NoShanghai cell collectionHuman breast cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOISignificant reduction in cell growthNoNoNA No responseNAVirus induced apoptosis in cancer cellNANA26203222
OV_4082AdenovirusAdenovirus ZD55DNAAdenoviridaeVirus encoded with drosophila dNK geneNoVirus in combination with drug DFDC(10mg/kg)NoShanghai cell collectionHuman breast cell lineMCF-71.0E+4 cells per wellNAMTT assay1 MOISignificant reduction in cell growthNoNoNA No responseNAVirus induced apoptosis in cancer cellNANA26203222
OV_4150Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4151Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI60% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4152Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI60% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4153Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI25% cell viability after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4154Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI10% cell viability after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4155Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4156Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI40% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4157Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI30% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4158Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI10% cell viability after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4159Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI100% cell killing after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4160Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4161Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI60% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4162Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI50% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4163Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI5% cell viability after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4164Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay0.1 MOI100% cell killing after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4165Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4166Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI20% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4167Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI15% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4168Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI2% cell viability after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4169Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI100% cell killing after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4324AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman breast adenocarcinomaMCF-74000 cells per wellNAMTT assay10 pfu95.2 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4428Vesicular stomatitis virusRdBRNARhabdoviridaeVirus expressing VSVG epitope, with no dletion in HI-loop, no addition of linkerYesNoNoATCCHuman breast cancer cell lineMCF-71.2E+4 cells per wellNAMTT assay21:1 particle to pfu48% cell survival after 4 daysNoNoNA No responseNANANANA26430798
OV_4436Vesicular stomatitis virusRdB-1L-VSVGRNARhabdoviridaeVirus expressing VSVG epitope, with no dletion in HI-loop, addition of single linkerYesNoNoATCCHuman breast cancer cell lineMCF-71.2E+4 cells per wellNAMTT assay24:1 particle to pfu1% cell survival after 4 daysNoNoNA No responseNANANANA26430798
OV_4477AdenovirusoAD/DCN-shMetDNAAdenoviridaeAdenovirus conjugated with DCN and shMetYesNoNoATCCHuman breast cancer cell lineMCF-770% confluence in 24 well plateNAMTT assay100 MOI88% cancer cell survivalability after 48 hoursNoNoNA No responseNANAIncreased in IL-6 level to 140pg/ml compared to control 20 pg/mlNA26951927
OV_4478AdenovirusoAD/DCN-shMet/PPDNAAdenoviridaeAdenovirus conjugated with DCN, shMet and PEGylated at PAMAMYesNoNoATCCHuman breast cancer cell lineMCF-770% confluence in 24 well plateNAMTT assay100 MOI85% cancer cell survivalability after 48 hoursNoNoNA No responseNANAIncreased in IL-6 level to 40pg/ml compared to control 20 pg/mlNA26951927
OV_4479AdenovirusoAD/DCN-shMet/PPEDNAAdenoviridaeAdenovirus conjugated with DCN, shMet and Erbitux-conjugated PEGylated at PAMAMYesNoNoATCCHuman breast cancer cell lineMCF-770% confluence in 24 well plateNAMTT assay100 MOI82% cancer cell survivalability after 48 hoursNoNoNA No responseNANAIncreased in IL-6 level to 40pg/ml compared to control 20 pg/mlNA26951927
OV_5344Newcastle disease virusLaSotaRNAParamyxoviridaeNoneYesNoNoATCCHuman mammary gland adenocarcinomaMCF-75.0E+4 cells per wellNAMTT assay0.001 MOI44% cells remain viable after 72 hoursNoNoNA No responseNAVirus induce apoptosisInduced production of IFN-alpha, IFN-beta, IL-6and IFN-gammaNA28293547
OV_5552ReovirusReovirus serotype 3RNAReoviridaeNoneYesNoNoATCCHuman breast cancer cell lineMCF-760% confluencyNANA40 MOICell viability drops from 93 to 16% after 72 hoursNoNoNA No responseNAInduction of apoptosis by virus infectionNANAUS6994858