| Primary information |
|---|
| OV_ID | OV_4166 |
| Virus Name | Measles virus |
| Strain | MV-s-NAP |
| Virus type | RNA |
| Virus family | Paramyxoviridae |
| Modification in virus genome | Genetically engineered for expressing H.pylori neutophil activating protein |
| Virus alone | No |
| Virus in combination iwth drug/radiation | Virus in combination with Alisertib (70nM) before 48 hours of MV infection |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human breast cancer cell line |
| Cell line | MCF-7 |
| Concentration of cell line | 5000 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 1 MOI |
| In-vitro result | 20% cell viability after 48 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Virus induce apoptosis process leads to cancer cell death |
| Immunogenic effect | Virus and drug both cause induction of IL-24 expression |
| Clinical trial | In clinical trials |
| PMID | 26272026 |