Detailed description page of Selected OV_ID


OV_2225 details
Primary information
OV_IDOV_2225
Virus Name Herpes simplex virus
StrainHSV-1-G47-delta
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant for Gamma34.5, ICP6 and alpha47 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineState key laboratory of oncology China
Origin of cell lineHuman breast cancer cell line
Cell lineMCF-7
Concentration of cell line1
In-vitro toxicityNA
AssayX-gal staining and MTT assay
In-vitro virus concentration0.01 MOI
In-vitro result40% cell survival after day 4
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionCaspase activation
Immunogenic effectNA
Clinical trialNA
PMID22108767