Detailed description page of Selected OV_ID


OV_4479 details
Primary information
OV_IDOV_4479
Virus Name Adenovirus
StrainoAD/DCN-shMet/PPE
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAdenovirus conjugated with DCN, shMet and Erbitux-conjugated PEGylated at PAMAM
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman breast cancer cell line
Cell lineMCF-7
Concentration of cell line70
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration100 MOI
In-vitro result82% cancer cell survivalability after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectIncreased in IL-6 level to 40pg/ml compared to control 20 pg/ml
Clinical trialNA
PMID26951927