Detailed description page of Selected OV_ID


OV_4167 details
Primary information
OV_IDOV_4167
Virus Name Measles virus
StrainMV-s-NAP
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeGenetically engineered for expressing H.pylori neutophil activating protein
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with Alisertib (70nM) before 48 hours of MV infection
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman breast cancer cell line
Cell lineMCF-7
Concentration of cell line5000
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration1 MOI
In-vitro result15% cell viability after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce apoptosis process leads to cancer cell death
Immunogenic effectVirus and drug both cause induction of IL-24 expression
Clinical trialIn clinical trials
PMID26272026